Özkan, Ozan

Profile Picture
Profile URL
https://hdl.handle.net/20.500.14411/7175
Name Variants
O., Özkan
O.,Ozan
Ozkan,O.
Ozan, Ozkan
Özkan,O.
O.,Özkan
Ozkan, Ozan
Özkan, Ozan
Ö.,Ozan
O., Ozkan
Ozan, Özkan
O., Ozan
Ö., Ozan
O.,Ozkan
Job Title
Doktor Öğretim Üyesi
Email Address
ozan.ozkan@atilim.edu.tr
Main Affiliation
Metallurgical and Materials Engineering
Status
Website
ORCID ID
Scopus Author ID
57189848353
Turkish CoHE Profile ID
Google Scholar ID
WoS Researcher ID
IUF-1471-2023

Sustainable Development Goals

NO POVERTY1
NO POVERTY
0
Research Products
ZERO HUNGER2
ZERO HUNGER
0
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GOOD HEALTH AND WELL-BEING3
GOOD HEALTH AND WELL-BEING
2
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QUALITY EDUCATION4
QUALITY EDUCATION
0
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GENDER EQUALITY5
GENDER EQUALITY
0
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CLEAN WATER AND SANITATION6
CLEAN WATER AND SANITATION
0
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AFFORDABLE AND CLEAN ENERGY7
AFFORDABLE AND CLEAN ENERGY
0
Research Products
DECENT WORK AND ECONOMIC GROWTH8
DECENT WORK AND ECONOMIC GROWTH
0
Research Products
INDUSTRY, INNOVATION AND INFRASTRUCTURE9
INDUSTRY, INNOVATION AND INFRASTRUCTURE
0
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REDUCED INEQUALITIES10
REDUCED INEQUALITIES
0
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SUSTAINABLE CITIES AND COMMUNITIES11
SUSTAINABLE CITIES AND COMMUNITIES
0
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RESPONSIBLE CONSUMPTION AND PRODUCTION12
RESPONSIBLE CONSUMPTION AND PRODUCTION
0
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CLIMATE ACTION13
CLIMATE ACTION
0
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LIFE BELOW WATER14
LIFE BELOW WATER
0
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LIFE ON LAND15
LIFE ON LAND
0
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PEACE, JUSTICE AND STRONG INSTITUTIONS16
PEACE, JUSTICE AND STRONG INSTITUTIONS
0
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PARTNERSHIPS FOR THE GOALS17
PARTNERSHIPS FOR THE GOALS
0
Research Products
Documents

6

Citations

125

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6

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Documents

8

Citations

138

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Scholarly Output

7

Articles

7

Views / Downloads

31/0

Supervised MSc Theses

0

Supervised PhD Theses

0

WoS Citation Count

114

Scopus Citation Count

97

Patents

0

Projects

0

WoS Citations per Publication

16.29

Scopus Citations per Publication

13.86

Open Access Source

1

Supervised Theses

0

JournalCount
Journal of Nanoscience and Nanotechnology2
International Journal of Pharmaceutics1
International Journal of Polymeric Materials and Polymeric Biomaterials1
Journal of Biomaterials Applications1
Journal of Bioscience and Bioengineering1
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Subject: PCL

Scholarly Output Search Results

Now showing 1 - 2 of 2
  • Thumbnail Image
    Article
    Citation - WoS: 24
    Antibacterial Performance of Pcl-Chitosan Core-Shell Scaffolds
    (Amer Scientific Publishers, 2018) Ozkan, Ozan; Sasmazel, Hilal Turkoglu
    In this study, antibacterial performance of the coaxially electrospun Poly-epsilon-caprolactone (PCL)-chitosan core-shell scaffolds developed, optimized and identified physically and chemically in our previous study, were evaluated for the suitability in wound healing applications. The aim of utilizing a core-shell fibrous scaffold with PCL as core and chitosan as shell was to combine natural biocompatibility, biodegradability and antibacterial properties of chitosan with mechanical properties and resistance to enzymatic degradation of PCL. The scaffolds were prepared with the optimized parameters, obtained from our previous study. Thickness and contact angle measurements as well as Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM) analyses confirmed repeated fabrication of PCL-chitosan core-shell scaffolds. In this study, assays specific to wound dressing materials, such as water vapor transmission rate (WVTR), in vitro degradability and antibacterial tests were carried out. WVTR value of PCL-chitosan core-shell scaffolds was higher (2315 +/- 3.4 g/m(2).day) compared to single PCL scaffolds (1654 +/- 3.2 g/m(2).day) due to the higher inter-fiber pore size. Additionally, in vitro degradability assays showed that the susceptibility of chitosan to enzymatic degradation can be significantly improved by hybridization with more resistant PCL while still keeping the scaffold to be considered as biodegradable. Finally, inhibition ratio and inhibition zone measurements showed that the PCL-chitosan core-shell polymeric scaffolds had significant antibacterial performance (52.860 +/- 2.298% and 49.333 +/- 0.719% inhibition ratios; 13.975 +/- 0.124 mm and 12.117 +/- 0.133 mm clear inhibition zones, against E. coli and S. aureus, respectively), close to the native chitosan. Therefore, the developed scaffolds can be considered as suitable candidates for biodegradable wound dressing applications.
  • Thumbnail Image
    Article
    Citation - WoS: 6
    Citation - Scopus: 7
    Hybrid Polymeric Scaffolds Prepared by Micro and Macro Approaches
    (Taylor & Francis As, 2017) Ozkan, Ozan; Sasmazel, Hilal Turkoglu; Turkoglu Sasmazel, Hilal
    Polymeric scaffolds with complex porous structures were fabricated with two different polymers by combining three fabrication methods in three steps, in which, nonwoven poly(e-caprolactone) microfibers were obtained with electrospinning and immersed in solvent cast chitosan solution poured in Petri dish to fabricate hybrid polymers, and finally the combined structure was freeze-dried with two different predrying techniques to obtain macropores in the structure. The resulting hybrid polymeric mats were found to have both microfibers and macroporosity due to the electrospinning as well as freeze-drying processes, which resemble the natural extracellular matrix. The optimized scaffolds that predried in the incubator at 40 degrees C for 5 h and then freeze-dried for 24 h exhibited contact angle value of 68.93 +/- 2.18 degrees with 3.252 +/- 0.783 MPa Young's modulus and 0.260 +/- 0.002 MPa yield strength as well as 1.35-fold cell yield in MRC5 fibroblast cell culture, compared to the commercial tissue culture polystyrene. [GRAPHICS] .