Aktaş, Zeynep
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Aktaş Z.
Z., Aktaş
A., Zeynep
Aktaş,Z.
Aktas Z.
Aktaş, Zeynep
Zeynep, Aktaş
Z.,Aktas
Z.,Aktaş
Aktas, Z.
A.,Zeynep
Zeynep, Aktas
Z., Aktas
Aktas, Zeynep
Aktas,Z.
Z., Aktaş
A., Zeynep
Aktaş,Z.
Aktas Z.
Aktaş, Zeynep
Zeynep, Aktaş
Z.,Aktas
Z.,Aktaş
Aktas, Z.
A.,Zeynep
Zeynep, Aktas
Z., Aktas
Aktas, Zeynep
Aktas,Z.
Job Title
Profesor Doktor
Email Address
zeynep.aktas@atilim.edu.tr
Main Affiliation
Surgical Sciences
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Website
ORCID ID
Scopus Author ID
Turkish CoHE Profile ID
Google Scholar ID
WoS Researcher ID
Sustainable Development Goals
2
ZERO HUNGER
0
Research Products
11
SUSTAINABLE CITIES AND COMMUNITIES
0
Research Products
14
LIFE BELOW WATER
0
Research Products
6
CLEAN WATER AND SANITATION
0
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1
NO POVERTY
0
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5
GENDER EQUALITY
0
Research Products
9
INDUSTRY, INNOVATION AND INFRASTRUCTURE
0
Research Products
16
PEACE, JUSTICE AND STRONG INSTITUTIONS
0
Research Products
17
PARTNERSHIPS FOR THE GOALS
1
Research Products
15
LIFE ON LAND
0
Research Products
10
REDUCED INEQUALITIES
0
Research Products
7
AFFORDABLE AND CLEAN ENERGY
1
Research Products
8
DECENT WORK AND ECONOMIC GROWTH
0
Research Products
4
QUALITY EDUCATION
0
Research Products
12
RESPONSIBLE CONSUMPTION AND PRODUCTION
0
Research Products
3
GOOD HEALTH AND WELL-BEING
0
Research Products
13
CLIMATE ACTION
0
Research Products
Documents
91
Citations
995
h-index
18
Documents
78
Citations
729
Scholarly Output
16
Articles
13
Views / Downloads
81/0
Supervised MSc Theses
0
Supervised PhD Theses
0
WoS Citation Count
68
Scopus Citation Count
86
WoS h-index
4
Scopus h-index
5
Patents
0
Projects
0
WoS Citations per Publication
4.25
Scopus Citations per Publication
5.38
Open Access Source
9
Supervised Theses
0
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| Journal | Count |
|---|---|
| Journal of Glaucoma | 3 |
| Turkish Journal of Ophthalmology | 2 |
| Graefe's Archive for Clinical and Experimental Ophthalmology | 2 |
| Turkish Journal of Clinical and Experimental Ophthalmology | 2 |
| Frontiers in Ophthalmology | 1 |
Current Page: 1 / 3
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16 results
Scholarly Output Search Results
Now showing 1 - 10 of 16
Article Surgical Treatment of a Patient With Recurrent Bleb Leak and Glaucoma: Bleb Excision Combined With Gonioscopy-Assisted Transluminal Trabeculotomy(Galenos Publ House, 2022) Boluk, Ceyda Eristi; Aktas, ZeynepHere we present a case of intermittent bleb leakage with increased intraocular pressure (IOP) during recovery periods that was treated with gonioscopy-assisted transluminal trabeculotomy (GATT) combined with avascular bleb excision. A 60-year-old woman exhibiting simultaneous leaking bleb and glaucoma underwent GATT and bleb revision. At her final visit, the bleb leakage had resolved and IOP was under control without any further antiglaucoma medication. GATT may be useful for glaucoma patients exhibiting intermittent bleb leakage after failed trabeculectomy.Article Citation - WoS: 14Citation - Scopus: 16Efficacy and Safety of Gonioscopy-Assisted Transluminal Trabeculotomy for Primary Congenital Glaucoma(Lippincott Williams & Wilkins, 2023) Aktas, Zeynep; Ozmen, Mehmet C.; Ozdemir Zeydanli, Ece; Oral, Merve; Eskalen, OguzcanPrecis:Gonioscopy-assisted transluminal trabeculotomy (GATT) provided effective intraocular pressure (IOP) control in primary congenital glaucoma (PCG). Also, approximately two third of patients did not need antiglaucoma medication at an average follow-up of 1 year after surgery. Purpose:The purpose of this study was to assess the safety and efficacy of GATT surgery in eyes with PCG. Materials and Methods:This study is a retrospective review of patients who underwent GATT surgery for PCG. Outcome measures were changes in IOP and number of medications at all time points (1, 3, 6, 9, 12, 18, 24, and 36 mo after surgery), and success rates. Success was defined as IOP<21 mm Hg with at least a 30% reduction from the baseline, complete if without medications, or qualified if with or without medications. Cumulative success probabilities were analyzed using the Kaplan-Meier survival analyses. Results:Twenty-two eyes of 14 patients diagnosed with PCG were enrolled in this study. The mean IOP reduction was 13.1 mm Hg (57.7%) with a mean decrease of 2 glaucoma medications at the final follow-up. All mean IOP readings during postoperative follow-up were significantly lower than baseline (P<0.05 for all). Cumulative probability of qualified success was 95.5% and the cumulative probability of complete success was 66.7%. Conclusion:GATT was safe and successfully lowered IOP in patients with PCG with the advantage of avoiding conjunctival and scleral incisions.Article Citation - Scopus: 2Gonioscopy-assisted transluminal trabeculotomy for congenital glaucoma secondary to Klippel-Trenaunay-Weber Syndrome: A case report(Elsevier Inc., 2022) Haidu,S.-D.; Aktas,Z.Purpose: To describe the case of a 9-year-old boy with congenital glaucoma secondary to Klippel – Trenaunay - Weber Syndrome (KTW) with a history of trabeculotomy in both eyes (BE) and further trabeculectomy in the left eye (LE) presented with high intraocular pressure (IOP) and progression in the LE despite maximum tolerated medical therapy. Observations: GATT surgery was performed firstly in the LE, followed by the right eye (RE) two months apart since the IOP in the RE started to increase later on. First post-operative day the IOP was under 15 mmHg. In the last visit, 6 months after the first surgery, IOPs were 10 and 11 mmHg RE and LE, on one fixed combination; slit lamp examinations were normal with wide open angles and a good view of the Schlemm's Canal (SC) posterior wall. Conclusions and Importance: GATT surgery can be done after failed incisional surgery in children with glaucoma secondary to KTW syndrome. © 2022 The AuthorsReview Citation - WoS: 9Citation - Scopus: 11Current Surgical Techniques for the Management of Pediatric Glaucoma: a Literature Review(Frontiers Media Sa, 2023) Aktas, Zeynep; Ikiz, Gokcen Deniz Gulpinar; Surgical Sciences; Surgical SciencesPediatric glaucoma surgery is challenging due to its diverse and complex pathophysiology, altered anterior segment anatomy, greater potential for failure, and complications compared to adult patients. Moreover, numerous challenges are associated with long-term postoperative management. Thus, when dealing with childhood glaucoma, it is important to consider the potential complications in addition to the benefits of each intervention. The purpose of this article is to review recently published literature to shed light on the most recent surgical techniques for the safe and effective treatment of childhood glaucoma. Current literature shows that goniotomy and trabeculotomy are the first choices for the management of primary congenital glaucoma. Although older children with phakic eyes seem to benefit from trabeculectomy with adjunctive mitomycin C, it carries a long-term risk of bleb-related endophthalmitis. Glaucoma drainage devices may be preferred for patients with secondary or refractory glaucoma. However, hypotony or tube-related complications are common and encountered more often in children than in adults. Cyclodestructive procedures are also an option for cases in which filtering surgery has failed, but they can also be used as a temporizing measure to reduce the rate of complications in high-risk patients. However, their outcomes can be unpredictable, in terms of efficiency and complications. Finally, minimally invasive glaucoma surgery (MIGS) as the sole alternative treatment or as an adjunctive surgical procedure is a relatively new path for pediatric patients.Article Evaluating Peripapillary Vessel Density and Retinal Nerve Fiber Layer Thickness in Pseudoexfoliation Syndrome: a Comparative Study(2025) Arıbaş, Yavuz Kemal; Aktaş, Zeynep; Segawa, AsaduPurpose: To evaluate the changes in the peripapillary vessel density and retinal nerve fiber layer thickness changes in pseudoexfoliation syndrome compared to healthy controls. Methods: The changes were studied in thirty eyes of thirty patients with pseudoexfoliation syndrome using optical coherence tomography angiography. Peripapillary vessel densities and peripapillary nerve fiber layer thicknesses were used to compare the optic nerve head characteristics in eyes with PSX and twenty-five healthy control eyes. Results: Average, superior, and inferior RNFL thicknesses were similar in both groups (p:0.055, p:0.052, p:0.116 respectively). Eyes with PSX had lower VD values compared to healthy control groups in peripapillary, superior, and inferior segments. (p:0.011, p:0.013, p:0.017 respectively). There were significant positive correlations between RNFL thickness and peripapillary vessel density in their corresponding sectors except for inferotemporal and temporal superior sectors. (p<0.05 except inferotemporal and temporal-superior sectors) Conclusion: In this study, peripapillary vessel density was found lower in eyes with pseudoexfoliation syndrome compared to age and systemic co-morbidity matched control group. These findings suggest that reduced peripapillary vessel density which may lead to ischemia might cause vulnerability to glaucomatous damage at the optic nerve head. However, further research needs to be done to establish whether the reduction of vessel density is associated with the progression to the pseudoexfoliation glaucoma and increased vulnerability to the glaucomatous damage.Article Citation - WoS: 1Citation - Scopus: 1Gonioscopy-Assisted Transluminal Trabeculotomy Versus Bent Ab Interno Needle Goniectomy in Patients With Open-Angle Glaucoma(Galenos Publ House, 2025) Ucgul, Ahmet Yucel; Ucgul, Rukiye Kilic; Aktas, ZeynepAmaç: Açık açılı glokomlu (AAG) hastalarda gonyoskopi yardımlı translüminal trabekülotomi (GATT) ile eğik iğne ab interno gonyektominin (BANG) etkinlik ve güvenliğini karşılaştırmak. Gereç ve Yöntem: Bu retrospektif karşılaştırmalı çalışma, GATT (34 göz) veya BANG (31 göz) uygulanan AAG tanılı 65 gözü içermektedir. Göz içi basınç (GİB), başlangıçta ve postoperatif takip vizitlerinde Goldmann applanasyon tonometresi ile ölçüldü. Cerrahi başarı, kısmi (GİB ≤21 mmHg ve ≥%20 azalma) ve tam (aynı kriterler ilaçsız) olarak kategorize edildi. Komplikasyonlar ve ek cerrahi gereksinimi not edildi. Bulgular: Ameliyat öncesi ortalama GİB, GATT grubunda 32,9±6,1 mmHg iken, BANG grubunda 31,8±5,4 mmHg idi. Son kontrolde, GATT grubunda ortalama GİB 15,8±4,5 mmHg’ye düşerken (%51,9 azalma), BANG grubunda 17,9±5,7 mmHg’ye (%43,7 azalma) düştü. Tam cerrahi başarı oranı GATT prosedürü için %88,2, BANG prosedürü için %61,3’tü. Erken cerrahi başarısızlıklar BANG grubunda daha sık görülürken, GATT grubunda erken başarısızlıklar daha nadir olsa da, geç dönemde cerrahi başarısızlıklar BANG grubuna göre daha sık izlendi. Her iki prosedürde de minimal komplikasyonlar görülmüş olup; en yaygın komplikasyon ise geçici hifemaydı. Sonuç: Bu çalışmada, GATT cerrahisinin, BANG cerrahisine kıyasla daha büyük ve daha sürdürülebilir GİB azalması sağladığı ve daha yüksek cerrahi başarı oranlarına sahip olduğu dikkate alındığında, AAG’nin yönetiminde GATT’ın daha güvenilir bir seçenek olduğu söylenebilir.Article Citation - WoS: 3Citation - Scopus: 3Risk Factors for Trabeculotomy Failure in Primary Congenital Glaucoma(Lippincott Williams & Wilkins, 2022) Aktas, Zeynep; Ucgul, Ahmet Y.; Boluk, Ceyda E.; Atalay, Hatice T.Precis:This study demonstrates that a baseline corneal diameter >12.25, initial age <4 months at diagnosis, higher baseline IOP than 24 mm Hg, bilaterality, or inability to perform circumferential trabeculotomy, increases the risk of surgical failure of trabeculotomy in patients with primary congenital glaucoma (PCG). Purpose:The aim of this study was to identify clinical predictive factors for surgical failure and to evaluate potential prognostic factors affecting surgical success in patients with PCG who underwent trabeculotomy. Patients and Methods:The medical charts of 123 eyes of 75 patients who underwent trabeculotomy surgery for the treatment of PCG were retrospectively reviewed. At baseline and each visit, intraocular pressure (IOP), corneal diameter, cup to disc ratio, axial length, number of medications, and need for further glaucoma surgery were noted. Surgical success was defined as an IOP <= 18 mm Hg and 20% IOP reduction from baseline with (qualified) or without (complete) medication and without any further IOP-lowering surgery. Results:The mean age at surgery was 4.2 +/- 6.6 months and the mean follow-up time was 60.0 +/- 37.6 months. The receiver operating characteristic curve showed 4 following best cutoff values to predict surgical failure: the first for age at surgery was 4.5 months; the second baseline IOP was 24.0 mm Hg; the third for baseline cup to disc ratio was 0.4; and the fourth for baseline corneal diameter was 12.25 mm. Multivariate logistic regression analysis revealed that baseline IOP more than 24 mm Hg increased the risk of surgical failure by 2 times, baseline mean corneal diameter >12.25 mm did by 4.2 times, younger age than 4 months did by 2.5 times, bilaterality did by 1.5 times. Conclusions:A higher baseline IOP, younger age, larger corneal diameter, and bilaterality were identified as risk factors for trabeculotomy failure in congenital glaucoma. The presence of one or more of these should be considered in the decision-making process when considering surgical options to manage glaucoma in these patients.Article Citation - Scopus: 1Outcomes of Gonioscopy-Assisted Transluminal Trabeculotomy in Children with Early-Onset Glaucoma Secondary To Sturge-Weber Syndrome(Elsevier, 2025) Aktas, Zeynep; El Sayed, Yasmine; Ucgul, Ahmet Yucel; Gawdat, Ghada; Elhilali, Hala; Aboalazayem, FayrouzPurpose: To evaluate the effectiveness and safety of gonioscopy-assisted transluminal trabeculotomy (GATT) in managing early-onset glaucoma secondary to Sturge-Weber syndrome (SWS). Design: A retrospective interventional case series. Participants: Medical records of 16 patients (22 eyes) diagnosed with early-onset glaucoma secondary to SWS who underwent GATT surgery were reviewed. Methods: All patients underwent GATT surgery using a 5-0 or 6-0 prolene suture under general anesthesia. Main Outcome Measures: The primary outcomes were intraocular pressure (IOP) reduction, complete surgical success (IOP <= 18 mmHg without medications), qualified surgical success (IOP <= 18 mmHg with medications), and postoperative complications. Results: The mean IOP decreased significantly from 25.4 +/- 4.8 mmHg at baseline to 15.7 +/- 4.2 mmHg at the final follow-up (P < 0.001), representing a 38.19% reduction. The mean age at the time of GATT surgery was 33.6 +/- 33.9 months. The mean follow-up duration was 16.3 +/- 6.4 months. Complete surgical success was achieved in 45.4% of eyes (10 out of 22), while qualified success was reached in 81.8% of eyes (18 out of 22). Despite the overall success, 18.1% of eyes (4 eyes) required additional surgical interventions during the follow-up period. These included Ahmed glaucoma valve implantation in 1 eye, trabeculectomy in 2 eyes, and transscleral diode laser cyclophotocoagulation in 1 eye. Transient hyphema was the only reported complication, resolving spontaneously within 1 week without further intervention. Conclusions: Gonioscopy-assisted transluminal trabeculotomy appears to be a promising surgical option for managing early-onset glaucoma in patients with SWS, offering significant IOP reduction and a favorable safety profile within the limitations of our study. However, further studies with longer follow-up periods and comparative groups are necessary to confirm these findings.Article Revolutionizing Glaucoma Care: Harnessing Artificial Intelligence for Precise Diagnosis and Management(2025) Ucgul, Ahmet Yucel; Aktas, ZeynepGlaucoma is a leading cause of irreversible blindness worldwide, necessitating early detection and effective management to prevent vision loss. Recent advancements in artificial intelligence (AI) have revolutionized glaucoma care by enhancing diagnostic accuracy, monitoring disease progression, and personalizing treatment strategies. AI models, including machine learning and deep learning algorithms, have demonstrated exceptional performance in analyzing fundus photography, optical coherence tomography, and visual field data, surpassing traditional diagnostic methods. Convolutional neural networks have shown high sensitivity and specificity in detecting glaucomatous changes, while vision transformers and hybrid AI models further refine risk assessment and prognosis. Additionally, AI- powered monitoring systems utilizing multi-modal data integration allow for more precise prediction of disease progression and the need for surgical intervention. The incorporation of AI into telemedicine and wearable intraocular pressure sensors extends glaucoma management to remote and underserved populations. Despite these advancements, challenges remain, including issues related to algorithm generalizability, data standardization, bias, and ethical concerns regarding AI-driven clinical decision-making. To maximize AI’s potential in glaucoma care, further interdisciplinary research, regulatory oversight, and multi-center validation studies are needed. By addressing these challenges, AI can be effectively integrated into clinical practice, leading to improved early detection, enhanced treatment strategies, and more personalized patient care. The future of AI in glaucoma management holds great promise, paving the way for a more data-driven and patient-centered approach to combating this sight-threatening disease.Correction Correction: Evaluating Anterior Segment Stability and Corneal Endothelium After Prolene Gonioscopy Assisted Transluminal Trabeculotomy (GATT) in Open-Angle Glaucoma(Springer, 2025) Aribas, Yavuz Kemal; Aktas, Zeynep; Ertop, Mestan
