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Permanent URI for this collectionhttps://hdl.handle.net/20.500.14411/18

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Start date: 2010Publisher: search.filters.publisher.Wiley

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Now showing 1 - 10 of 185
  • Article
    Nutritional Composition, Phenolic Constituents, and Antioxidant Activity of the Edible Desert Truffle Terfezia Claveryi (Chatin)
    (Wiley, 2026-01) Bulut, Onur; Altunbas, Osman; Sonmez, Cagla
    The edible desert truffle, Terfezia claveryi, is a highly valued wild macrofungal species native to the semiarid regions of Central Anatolia. This study provides molecular identification and a comprehensive biochemical evaluation of T. claveryi, using lyophilized material to assess its nutritional composition, phenolic profile, and antioxidant potential. Proximate analysis revealed high carbohydrate (69.93 +/- 1.69%) and moderate protein (13.8 +/- 0.55%) contents, a low lipid level (3.45 +/- 0.14%), and notably high vitamin C concentration (86.90 +/- 0.33 mg 100 g(-1) DW). Linoleic (C18:2%, 67.63%), oleic (C18:1%, 17.29%), and palmitic (C16:0%, 10.81%) acids predominated in the fatty acid profile. Amino acid analysis showed an exceptionally high lysine proportion (30.9% of total amino acids) and an essential-to-nonessential amino acid ratio (1.64) exceeding the FAO/WHO reference value, indicating superior protein quality. Mycotoxins were not detected using chromatographic methods, confirming the safety of the samples. Solvent extracts of lyophilized T. claveryi were prepared using methanol-water and acetone-water mixtures at varying ratios, as well as ethyl acetate and hexane. Total phenolic and flavonoid contents were highest in aqueous methanol and acetone extracts, which also exhibited strong radical scavenging and reducing activities in DPPH, FRAP, and ABTS assays. RP-HPLC analysis identified gallic acid, rutin, quercetin, and vanillic acid as major phenols, with gallic acid being predominant (154.81 +/- 5.50 mu g g(-1) DW). A strong correlation (R-2 > 0.95; p < 0.001) was observed between phenolic content and antioxidant capacity. Overall, T. claveryi represents a safe, nutrient-rich, and phenolic-dense functional food with significant potential to complement lysine-deficient cereal-based diets.
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    Machine Learning Outperforms Traditional Methods in Predicting Kidney Transplant Outcomes: A Multicentre Cohort Study
    (Wiley, 2026) Dheir, Hamad; Demir, Erol; Celtik, Aygul; Hosseini, Seyed Amir Tabatabaei; Kocak, Huseyin; Cakir, Ulkem; Sinangil, Ayse
  • Article
    Novel Enterococcus Phages Identified through Comprehensive Screening to Control Contamination in Chicken Meat
    (Wiley, 2026-03-25) Unal, Gultekin; Cengiz, Gorkem; Cufaoglu, Gizem; Acar, Bahar Onaran; Ayaz, Naim Deniz; Yildiz, Tansu; Erdinc, Ayse Nur; Onaran Acar, Bahar
    BACKGROUND Antibiotic-resistant Enterococcus faecalis and E. faecium are persistent contaminants in food and environmental settings, including poultry-related matrices, contributing to food safety risks and antimicrobial resistance (AMR) dissemination. This study aimed to identify Enterococcus phages through environmental screening and evaluate their biocontrol potential using a chicken wing food model. RESULTS From 1719 environmental samples, 45 Enterococcus-targeting phages were isolated, and two (Efs.1 1-1 and Efm 3-10) with the broadest lytic profiles were selected for characterization. Transmission electron microscopy revealed that both phages belong to Caudoviricetes with siphovirus-like morphology, latent periods (6-8 min), and high burst sizes (90-110 PFU per cell). Whole-genome sequencing revealed complete circular genomes with estimated completeness values between 0.97 and 1.00, and no detectable virulence, lysogeny, or AMR genes. The phages were stable at pH 4 for 60 min and tolerated 40-60 degrees C for 1 h. Phage titers decreased from 10.0 to no less than 6.0 log PFU mL(-1) across all storage conditions over 12 months. In vitro assays in tryptic soy broth showed that while the control groups reached 8.56-9.12 log CFU mL(-1) at 24 h at 37 degrees C, no bacteria were detected in any of the phage-treated samples (limit of detection: 1 CFU mL(-1)). In the chicken wing food model, phage treatment maintained bacterial counts below the detection limit (<1 log CFU g(-1)) throughout refrigerated storage. Mean log reductions reached 1.78-2.78 and 3.71-4.71 log CFU g(-1), respectively. CONCLUSION These novel lytic phages exhibit strong stability and rapid antibacterial activity, offering promising biocontrol agents to reduce Enterococcus contamination in chicken meat.
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  • Article
    On Optimal Allocation of Redundancies in Random Weighted Coherent Systems
    (Wiley, 2026-02-02) Sahoo, Tanmay; Hazra, Nil Kamal; Balakrishnan, Narayanaswamy
    Unlike the ordinary coherent systems, a random weighted coherent system captures components' disparity. Its performance is measured by some appropriate measure of contributions made by all of its components. In this paper, we consider random weighted coherent systems, defined based on the survival capacity, with three different survival mechanisms, namely, Types-I, II, and III. Then, we study the optimal active redundancy allocation policy as well as the optimal assembly method of random weights in a random weighted coherent system. We provide several numerical examples to illustrate all the results established here.
  • Article
    Skull Base Surgery in the Pediatric Population-The 2nd International Collaborative Study (1995-2015)
    (Wiley, 2026-02-11) Fliss, Dan M.; Ungar, Omer J.; Levyn, Helena; Valero, Cristina; Adilbay, Dauren; Eagan, Alana; Shah, Jatin P.
    Background The current study presents the efforts of a global collaborative group to review the management and outcomes of malignant tumors of the skull base in the pediatric population worldwide.Patients and Methods A total of 28 institutions contributed data on 3061 patients. From this, there were 64 pediatric patients (2.1%). Clinical variables, overall and disease-free survival (OS and DFS) outcomes, and multivariable factors associated with outcome were evaluated.Results The male-to-female ratio was 37:27 and the median [IQR] age at diagnosis was 14.0 [9.6-16.0] years. The most common malignancy was sarcoma (57.8%), followed by esthesioneuroblastoma (25.0%) and carcinoma (17.2%). Negative margins were achieved in 53.1% children. Dural invasion was associated with reduced OS and DFS. Adjuvant radiotherapy was associated with improved survival outcomes.Conclusions Open approaches were widely used for pediatric skull base tumor resection in the period between 1995 and 2015 but we saw a rise in the use of endoscopic and combined techniques by the end of the period covered by this study. Our results may represent a transitional era in which alternative endoscopic techniques continue to expand.
  • Article
    The Paradox of Power in Turkey: Omnipotent Leader, Impotent State
    (Wiley, 2026-02-18) Bektas, Eda; Muhurcuoglu, Korhan
    This article examines a central paradox of contemporary authoritarianism: how the concentration of power in the hands of a seemingly omnipotent executive can simultaneously erode bureaucratic capacity and autonomy through subordination, producing an increasingly impotent state. Focussing on Turkey's transition to hyper-presidentialism after the 2018 elections, it argues that excessive centralisation has undermined the institutional competence and discretion required for coordinated and effective policy implementation. The government's response to the 6 February 2023 twin earthquakes provides a tragic and revealing case that affected millions of lives. Despite Recep Tayyip Erdo & gbreve;an's pledges that the presidential system would deliver efficiency and decisiveness, disaster governance was marked by delayed decision making, poor coordination, limited capacity for rapid mobilisation and communication and an emphasis on narrative control over effective execution. Drawing on bureaucratic capacity and autonomy as indicators of governance quality, this article shows how personalist rule hollows out state institutions, exposing its limits in delivering good governance.
  • Article
    Real Interest Rate Parity in Latin American Countries: Evidence from New Panel Unit Root Tests
    (Wiley, 2026-02-21) Omay, Tolga; Abioglu, Vasif; Hasanli, Mubariz
    In this study, we test the empirical validity of the real interest rate parity hypothesis for 15 Latin American countries over the period 2005-2023. To this end, we employ a battery of panel unit root tests to examine stochastic properties of the real interest rate differentials (RIDs) of the countries under consideration. The panel unit root tests that allow for both the cross-sectional dependence and the nonlinearities in the adjustment process do not reject the null of unit root for the most of these countries, suggesting that the real interest rate parity hypothesis does not hold for these countries. On the other hand, the panel unit root test that allows for smooth structural changes produces results consistent with the real interest rate parity hypothesis for 12 out of 15 Latin American countries. These findings imply that various shocks, including political, economic, and financial upheavals, can cause significant structural shifts in the RIDs of Latin American countries.
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