Pubmed
Permanent URI for this collectionhttps://hdl.handle.net/20.500.14411/22
Browse
261 results
Search Results
Article Malnutrition, Diet Quality, and Psychological Well-Being in Older Adults: A Hospital Outpatient Study(BMC, 2026-02-17) Cihan, Berna Betul; Naharci, Mehmet Ilkin; Konyaligil, Dilara Bersan; Topkaya, Merve Sena; Tel Adiguzel, Kubra; Koc, NevraBackground The ageing process can lead to malnutrition due to a variety of physiological and psychological issues. Investigating nutrition, lifestyle and psychological status is important for improving the health of the geriatric. The aim of this study was therefore to evaluate the relationship between malnutrition, dietary quality and psychological well-being in older adults. Methods One hundred three older adults treated at the Gülhane Training and Research Hospital Geriatrics polyclinic participated in this cross-sectional study. The researchers recorded sociodemographic characteristics, health information, anthropometric measurements, the Short Nutritional Assessment Questionnaire for 65 + (SNAQ(65+)) screening test, the Mediterranean Diet Adherence Scale (MEDAS) and the Psychological Well-Being Scale for the Older People (YPIOA) using a questionnaire during face-to-face interviews. Generalised Anxiety Disorder-7 (GAD-7) test was administered to older adults who applied to the geriatrics outpatient clinic at the time of application; individuals who did not meet the criteria were excluded from the study. Results The results of the study showed that the psychological well-being scale scores of individuals who strictly adhered to the Mediterranean diet (mean = 68.1) were significantly higher than those of individuals who did not adhere to the Mediterranean diet (mean = 59.5)(p < 0.05). Linear regression was used to evaluate older adults according to their MEDAS and YPIOA values. The test results revealed a significant positive correlation between the MEDAS score and the YPIOA (p < 0.05). However, no significant difference was found between the groups when the relationship between the MEDAS and SNAQ(65+) scores of older adults was evaluated (p > 0.05). Conclusion According to the results of the study, geriatric people who scored higher on the MEDAS also scored higher on the YPIOA. However, no significant relationship was found between SNAQ(65+) and MEDAS scores. These findings suggest that the quality of an individual's diet may affect not only their physical health, but also their psychological well-being. Therefore, treatment plans for the nutritional needs of older adults should take into consideration not only energy and nutrient intake, but also the individual's lifestyle, habits and psychological status.Article Evaluation of Central Auditory Processing in Children with Developmental Dyslexia(Elsevier Ireland Ltd, 2026-03) Begen, Senanur Kahraman; Ciyiltepe, Muge Muzeyyen; Arslan, BerkayObjective: Developmental dyslexia is a neurodevelopmental disorder primarily characterized by phonological and reading difficulties. This study aimed to investigate temporal auditory processing and dichotic listening performance in children with developmental dyslexia and to explore their potential contribution to reading-related difficulties. Methods: Sixty children aged 8-13 years participated in the study, including 30 children diagnosed with developmental dyslexia and 30 age-matched typically developing peers. Central auditory processing was assessed using the Staggered Spondaic Word (SSW) test for dichotic listening and the Frequency Pattern Test (FPT), Duration Pattern Test (DPT), and Random Gap Detection Test (RGDT) for temporal auditory processing. Results: Children with developmental dyslexia demonstrated significantly poorer performance than controls across all temporal and dichotic auditory processing measures (p < 0.05). In the SSW test, the greatest performance difference was observed in the left competing condition. Temporal processing deficits were evident in frequency discrimination, duration pattern recognition, and gap detection tasks. Conclusion: Children with developmental dyslexia exhibit weaknesses in temporal and dichotic auditory processing tasks. Given the linguistic demands inherent in some dichotic measures, these findings likely reflect an interaction between auditory and language-related processing rather than isolated auditory pathway dysfunction. Incorporating central auditory processing assessment into multidisciplinary dyslexia evaluations may contribute to more targeted diagnostic and intervention approaches.Correction Rehabilitation in Neuromuscular Diseases: Best Turkish Practice Recommendations by Multidisciplinary Experts (Nov, 10.1007/S13760-025-02923-8, 2025)(Springer Heidelberg, 2026-01-28) Umay, Ebru; Tanigor, Goksel; Toraman, Fusun; Karaahmet, Ozgur; Bilgilisoy, Meral; Sertpoyraz, Filiz; Kasapoglu, BanuIn this article, a co-author name has been missed out in the original published version. The complete correct name is given below. Banu Kasapoğlu. The original article has been corrected. © The Author(s) under exclusive licence to Belgian Neurological Society 2026.Article Complex Multisource Sound Induces Greater Neurodegeneration in Neonatal Rat Brain than Single-Source Sound(Frontiers Media SA, 2026-01-28) Daltaban, Iskender Samet; Aydin, Mehmet Dumlu; Eyupoglu, Eylem Eren; Demirci, Elif; Okuyan, Aybike Aydin; Demir, Mehmet EminBackground: Excessive noise exposure is a known environmental health hazard linked to neurological injury and cognitive deficits. Whether complex sound waveforms from multiple sources exacerbate brain damage compared to a single-source noise of equal intensity remains unclear. We investigated the effects of identical music played either through one or four loudspeakers on the developing brain of newborn rats. Methods:<bold> </bold>Forty-one newborn Sprague-Dawley rat pups (both sexes), along with their dams, were randomly assigned to three groups: control (no noise, n = 6), single-speaker exposure (n = 15), and multi-speaker exposure (n = 20). From postnatal day 0 to 30, the exposure groups were subjected to an 8-min music track (similar to 85 dB SPL) either via one loudspeaker (simple waveform) or simultaneously via four loudspeakers (complex interfering waveform), six times daily at 4-h intervals. Sound intensity was calibrated at the cages with a sound-level meter. All procedures followed ARRIVE guidelines and the EU Directive 2010/63/EU for animal research, with institutional ethical approval. After 1 month, rat brains were examined histologically. Unbiased stereology was used to estimate neuronal densities in the temporal lobe (including amygdala and hippocampal dentate gyrus). Immunohistochemistry for neuron-specific enolase (NSE), glial fibrillary acidic protein (GFAP) and TUNEL assay (terminal deoxynucleotidyl transferase dUTP nick-end labeling) was performed to identify neuronal integrity, astroglial response, and apoptosis, respectively. Outcome measures were degenerated (TUNEL-positive) neuron densities and histopathological lesions. Statistical comparisons were made using Student's t-tests or ANOVA and chi-square tests (with p < 0.05 considered significant). Results: Eight of 20 pups (40%) in the multi-speaker group died during the exposure period, compared to 5/15 (33%) in the single-speaker group and 3/6 (50%) in controls (differences not statistically significant). Maternal rats exhibited agitation, stress behaviors, and weight loss under noise; some eventually ceased escape attempts (habituation/helplessness behavior) in both noise-exposed groups. Histologically, the multi-speaker exposure caused more severe brain injury than the single-speaker exposure. Pups in the multi-speaker group showed frequent subarachnoid hemorrhages and cortical microvascular bleeding in the temporal lobes, whereas these lesions were mild or infrequent in the single-speaker group and absent in controls. Neurons in noise-exposed brains displayed morphological signs of degeneration (shrunken, angulated cell bodies with pyknotic nuclei and condensed cytoplasm), which were markedly pronounced in the multi-speaker group. Stereological cell counting revealed a significant increase in apoptotic neuron density in both sound-exposed groups, with the multi-speaker group highest. For example, in the hippocampal dentate gyrus, the mean density of TUNEL-positive (degenerating) neurons was 13,450 +/- 1,560 per mm(3) in the multi-speaker group vs. 7,600 +/- 980 per mm(3) in the single-speaker group and only 200 +/- 34 per mm(3) in unexposed controls (p < 0.05). In the amygdala, apoptotic neuron density averaged 3,460 +/- 863 per mm(3) (multi-speaker) vs. 1,470 +/- 285 (single-speaker) and 1,321 +/- 234 (control), with the multi-speaker group showing a significantly higher burden of neuronal cell death (p < 0.005 for complex vs. simple waveforms). Correspondingly, multi-speaker exposed brains showed intense immunostaining for NSE and GFAP fragmentation, indicating widespread neuronal loss and reactive astroglial injury, whereas single-speaker exposure caused only moderate changes. Conclusion: Identical musical noise caused substantially more neurodegeneration in the developing brain when delivered as complex wave interference from multiple speakers rather than as a single-source sound of the same intensity. Complex multisource waveforms appear to amplify the harmful effects of noise on neonatal brain tissue, likely through interference-driven pressure fluctuations. These findings have clinical and public health implications, suggesting that current noise exposure guidelines should consider not only sound intensity and duration but also the acoustic complexity and source configuration, especially to protect vulnerable populations such as infants and children from high-intensity multisource noise environments.Article The Role of Emotional Intelligence in the Relationship between Burnout and Perceived Quality of Care Among Oncology Nurses(Elsevier Sci Ltd, 2026-02) Sari, Tugba; Calis, Behice Belkis; Pars, Hatice; Guner, Perihan; Çalışkan, Behice BelkısPurpose: This study aimed to examine the relationships between burnout, emotional intelligence, and perceived caring behaviours among oncology nurses and to assess the predictive and mediating roles of these variables in explaining caring behaviours. Methods: A descriptive, cross-sectional study was conducted with 202 oncology nurses in T & uuml;rkiye. Data were collected using validated instruments measuring burnout, emotional intelligence, and caring behaviors. Data analysis employed descriptive statistics, Pearson correlation analyses, multiple linear regression, and structural equation modeling. Results: Emotional intelligence was positively associated with caring behaviours (r = .359, p < .001) and negatively associated with burnout subdimensions. Caring behaviours were inversely related to emotional exhaustion (r = -.258, p < .001), depersonalisation (r = -.397, p < .001), and reduced personal accomplishment (r = -.214, p = .002). In the regression model (R2 = .214, p < .001), emotional intelligence significantly predicted caring behaviours positively ((3 = .218, p = .002), while depersonalisation was a significant negative predictor ((3 = -.288, p < .001). However, emotional intelligence did not mediate the relationship between burnout and caring behaviours (Sobel test p = .332). Conclusion: While emotional intelligence was positively associated with caring behaviours and buffered the impact of burnout-particularly depersonalisation-it did not mediate the relationship between burnout and caring. These findings support the value of enhancing emotional intelligence to improve care quality and nurse well-being, though contextual factors may influence its mediating role.Article Utilizing POCUS in the Diagnosis of Small Bowel Obstruction and the Barriers to Its Implementation in Resource-Limited Settings: A Systematic Review(Springer Int Publ AG, 2026-01-16) Razakh, Ayesha; Uzor, Angelina; Htoon, April; Valko, MichalPurposeSmall bowel obstruction (SBO) is a common surgical emergency that can lead to significant morbidity, mortality, and healthcare costs, particularly when diagnosis is delayed. In rural and resource-limited emergency settings, advanced imaging techniques like computed tomography (CT) may not be readily available. As a result, clinicians often rely on physical examinations and plain radiographs which can be unreliable. Point-of-care ultrasound (POCUS) provides a rapid, radiation-free and cost-effective diagnostic alternative that can be performed directly at the bedside.MethodsWe conducted a systematic review of published literature evaluating the diagnostic accuracy and clinical utility of POCUS in identifying SBO on the following databases PubMed, Web of Science, Cochrane Library and Google Scholar databases from January 2000 to December 2024. Studies were screened and selected based on the inclusion and exclusion criteria adhering to PRISMA 2020 guidelines.ResultsThe sensitivity of POCUS for SBO ranged from 85.0 to 100%, while specificity ranged from 54.0 to 100%. Diagnostic accuracy remained high across a broad range of expertise overcoming operator dependence. Examination durations are approximately 10-11 min, which is markedly shorter than 45-min to 3-h by CT.ConclusionPOCUS presents as a practical, scalable and cost-saving tool for diagnosing SBO in rural emergency care, addressing significant gaps where CT is not available and also facilitates faster diagnosis by timely identification of specific features. Future efforts should focus on developing validated algorithms for resource-limited settings allowing immediate care management.Article Comparison of Voice Call Based and Multimodal Telerehabilitation After Total Knee Arthroplasty: A Randomized Controlled Trial(Taylor & Francis Inc, 2026-01-21) Aslan, Sema Nur; Bozgeyik-Bagdatli, Sibel; Demirel, Murat; Atilla, Bulent; Kinikli, Gizem IremBackground Telerehabilitation has emerged as a promising approach in postoperative care following total knee arthroplasty(TKA);nevertheless,the relative effectiveness of different telerehabilitation modules is still under discussion, leaving room for alternative and multimodal program approaches. Objectives This study aimed to compare the effectiveness of a multimodal telerehabilitation(MTR) and voice call based telerehabilitation(VTR) in patients undergoing TKA. Methods A two-arm randomized controlled trial was conducted with 24 patients (68.42 +/- 9.28y) in the MTR group and 21(71.19 +/- 7.26y) in the VTR group. The MTR group received weekly digital booklets containing asynchronous exercise videos, one voice call, one video call,and text messages,for a total of three contacts per week. The VTR group received weekly printed booklets and voice calls three times a week(on alternate days) over the 8-week intervention period. Outcomes were assessed face to face at discharge, and at the 4th and 8th postoperative weeks. Measures included Visual Analog Scale(VAS), active and passive range of motion(ROM), Knee Osteoarthritis Outcome Score-Physical Function(KOOS-PS), Five Repetition Sit to Stand Test(5xSST), Brief Fear of Movement(BFoM) Scale, isometric Quadriceps muscle strength, Forgotten Joint Score-12(FJS-12),Exercise Adherence Rating Scale(EARS). The primary outcome was active knee flexion ROM. Statistical significance was set at p < .05; effect sizes (r, W) were reported for the Mann - Whitney U and Wilcoxon tests. Results After 8 weeks, a statistically significant difference in pain during activity was observed between the MTR and VTR groups (p < .001, r = 0.62). Both groups showed significant gains in active and passive knee flexion ROM, 5xSST, and KOOS-PS scores (all p < .001), while the MTR group also improved in rest pain, knee extension, and BFoM (all p < .001). At week 8, statistically significant differences were observed between the MTR and VTR groups across all outcome measures (all p < .001). Conclusion Both telerehabilitation approaches were effective in improving pain, ROM, and functional outcomes after TKA.Although this study did not compare outcomes with conventional in-person rehabilitation, MTR showed greater overall improvements than VTR. Nevertheless, VTR remains a reasonable alternative when MTR cannot be implemented.Article Trends and Scientific Evolution in Endovascular Aneurysm Repair (EVAR) Research: A Comprehensive Bibliometric Study Using Vosviewer(Sage Publications Inc, 2026-01-25) Sever, Sinem Nur; Oktem, Hale; Jamil, Yusuf; Pelin, CanBackground: Endovascular aneurysm repair (EVAR) has become a standard treatment for abdominal aortic aneurysms. However, the evolution of EVAR research and its global landscape remain underexplored. This bibliometric analysis aims to map publication trends, identify key contributors, and analyze thematic shifts in EVAR literature over the past three decades.Methods: Data were collected from the Web of Science Core Collection (SCIE) in May 2025. A total of 4264 original research articles on EVAR were analyzed using VOSviewer for co-authorship, co-citation, and keyword co-occurrence mapping. Citation trends, geographical distribution, and institutional contributions were also assessed.Results: Research on EVAR showed steady growth, with a peak of 295 publications in 2024. The United States contributed the largest share (33.02%) of publications. Prolific authors such as Schermerhorn and Verhagen, affiliated with leading institutions like Harvard University, played a pivotal role in advancing the field. Keyword analysis revealed a shift from technical terms (e.g., "stent graft") to clinical outcomes (e.g., "reintervention") over time. The integration of artificial intelligence (AI) in EVAR research is emerging as a key focus area.Conclusion: This study highlights the growth and evolving focus of EVAR research, with a notable shift toward patient-centered outcomes. Despite strong contributions from high-income countries, there is a significant gap in research from low-resource settings. Future directions should include addressing gaps in radiation safety, emergency EVAR applications, and exploring AI-driven clinical decision-making for personalized treatments. Complex EVAR research continues expanding, reflecting guideline evolution and advancing practice in anatomically challenging cases.Clinical Impact This bibliometric analysis demonstrates how EVAR has progressed from an emerging minimally invasive technique to a guideline driven standard of care, with a growing emphasis on complex fenestrated and branched procedures. For clinicians, the findings clarify where the evidence base is well established, particularly for standard infrarenal EVAR, and where further caution and innovation are required, including complex anatomies, long term durability, and reintervention risk. By synthesizing influential studies, key guideline milestones, and evolving research themes, this study supports evidence based clinical decision making, improves patient counseling, and reinforces the importance of lifelong surveillance. Its innovation lies in translating three decades of global research into clinically actionable insight.Article Comparison of the Effects of Breast Milk and Hamamelis Virginiana (Witch Hazel) on the Healing of Diaper Dermatitis in Infants: A Randomized Trial(Mary Ann Liebert, Inc, 2025-12-22) Sevimli Guler, Dondu; Vural, Gulsen; Turan, Zekiye; Unal Toprak, Filiz; Melek Arsoy, Hacer EfnanBackground: Diaper dermatitis (DD) is a very common problem in infants between 1 and 6 months. While it rarely causes long-lasting problems, it can cause serious short-term problems for both infants and parents. Accordingly, this study compared the effect of breast milk and diaper rash cream containing Hamamelis virginiana (12 mg/100 g) on the healing process in 0-6 month-old infants with DD. Methods: This randomized, single-blinded trial was conducted with 60 infants aged 0-6 months diagnosed with DD. Participants were assigned to either the breast milk group (BG) or the comparison group (CG) receiving Hamamelis virginiana cream. Demographic characteristics and DD severity were assessed using a structured demographic questionnaire and the validated Assessment of the Severity of Uncomplicated DD in Infants Scale. Statistical analyses included Shapiro-Wilk, Mann-Whitney U, Wilcoxon signed rank, Chi-square, and Fisher's exact tests. Significance was set at p < 0.05. Results: Before the intervention, the mean scale score was 5.17 +/- 0.46 in the BG, 2.83 +/- 1.37 in the CG, which was a statistically significant difference. After the intervention, there was a significant decrease in the mean scale score in the BG to 0.03 +/- 0.18, whereas the mean decrease was smaller in the CG (1.53 +/- 1.11). The difference in the mean scale scores between the groups was statistically significant (p < 0.001). Furthermore, the postintervention mean scale score of the BG was significantly lower than that of the CG. However, baseline severity differences limit direct comparison of treatment efficacy. Conclusions: Topically applied breast milk appears to be a safe, accessible, and cost-effective option for treating uncomplicated DD, with greater improvement than cream containing Hamamelis virginiana. However, baseline severity differences limit direct comparison. Further studies using block randomization are recommended.Article Effect of Freezing Phenomenon on Gait Parameters and Pedobarographic Pressure Distribution in Patients with Parkinson's Disease(Springer-Verlag Italia Srl, 2025-12-29) Korkusuz, Suleyman; Korkusuz, Busra Seckinogullari; Demircan, Emine Nur; Ozcan, Aysenur; Cakmakli, Gul Yalcin; Balkan, Ayla Fil; Elibol, BulentBackground This study aimed to examine the gait parameters of individuals with Parkinson's Disease with and without freezing of gait (FoG) on the treadmill, where freezing difficulty decreases. Methods Our study included three groups of demographically similar individuals: 15 patients with Parkinson's disease without freezing of gait, 14 patients with Parkinson's disease with freezing of gait, and 14 healthy controls. Spatiotemporal parameters of gait and static-dynamic pedobarographic pressure distribution analysis were performed using a computerized gait evaluation system (on a treadmill). Results The step length, gait speed and gait phase duration of the freezing of gait group were lower than the other groups (p < 0.05). While pedobarographic pressure distribution during static stance was similar in all groups (p > 0.05), pedobarographic pressure distribution during gait was different between groups (p < 0.05). Conclusion In patients with freezing of gait, gait speed was lower, step length and single support phase were shorter, and double support phase was longer. While the amount of load on the backfoot was lower in both Parkinson's groups, the amount of load on the forefoot was lower only in patients with freezing of gait. Even if freezing of gait did not occur, it was observed that the gait characteristics of Parkinson's disease with freezing of gait were different from those of Parkinson's disease without freezing of gait.