WoS

Permanent URI for this collectionhttps://ada.atilim.edu.tr/handle/123456789/18

Browse

Now showing 1 - 20 of 200

Citation - WoS: 14
Citation - Scopus: 13
3d Bioprinting Tissue Analogs: Current Development and Translational Implications
(Sage Publications inc, 2023) Liu, Suihong; Cheng, Lijia; Liu, Yakui; Zhang, Haiguang; Song, Yongteng; Park, Jeong-Hui; Ramalingam, Murugan
Three-dimensional (3D) bioprinting is a promising and rapidly evolving technology in the field of additive manufacturing. It enables the fabrication of living cellular constructs with complex architectures that are suitable for various biomedical applications, such as tissue engineering, disease modeling, drug screening, and precision regenerative medicine. The ultimate goal of bioprinting is to produce stable, anatomically-shaped, human-scale functional organs or tissue substitutes that can be implanted. Although various bioprinting techniques have emerged to develop customized tissue-engineering substitutes over the past decade, several challenges remain in fabricating volumetric tissue constructs with complex shapes and sizes and translating the printed products into clinical practice. Thus, it is crucial to develop a successful strategy for translating research outputs into clinical practice to address the current organ and tissue crises and improve patients' quality of life. This review article discusses the challenges of the existing bioprinting processes in preparing clinically relevant tissue substitutes. It further reviews various strategies and technical feasibility to overcome the challenges that limit the fabrication of volumetric biological constructs and their translational implications. Additionally, the article highlights exciting technological advances in the 3D bioprinting of anatomically shaped tissue substitutes and suggests future research and development directions. This review aims to provide readers with insight into the state-of-the-art 3D bioprinting techniques as powerful tools in engineering functional tissues and organs.
Citation - WoS: 1
Acting Locally: Local Environmental Mobilizations and Campaigns
(Sage Publications Ltd, 2013) Ozen, Hayriye; Department of Public Administration and Political Science
[No Abstract Available]
Citation - WoS: 0
Citation - Scopus: 0
Advances on Multivalued Operators and Related Fixed Point Problems
(Hindawi Publishing Corporation, 2014) Chen, Chi-Ming; Karapinar, Erdal; Du, Wei-Shih; Aydi, Hassen; Romaguera, Salvador; Mathematics
[No Abstract Available]
Citation - WoS: 2
Citation - Scopus: 3
Akciğer Kanserinde İmmünoterapi ve Tedavide Multidisipliner Yaklaşım
(Turkish Assoc Tuberculosis & Thorax, 2020) Karadurmuş, Nuri; Kaya, Akın; Göksel, Tuncay; Yılmaz, Ülkü; Tülek, Necla; Basic Sciences
Akciğer kanseri dünya genelinde kanserle ilişkili ölümlerin başlıca nedeniolmaya devam etmektedir. Son 20 yılda kanser biyolojisi ve patogenezi hakkındaki bilgiler artmış, immün kontrol noktası inhibitörleri (İKNİ) kullanımasunulmuş ve böylece solid kanserlerin tedavisinde önemli bir dönem başlamıştır. Bu derlemede; tedavide yenilikler, immünoterapi ve tedavide multidisipliner yaklaşım çerçevesinde akciğer kanseri ele alınmıştır. Küçük hücreli dışıakciğer kanseri (KHDAK) en sık görülen ve özellikleri nedeniyle İKNİ tedavisinden ideal olarak yararlanabilecek akciğer kanseri türü olması nedeniyleyazının odak noktasını oluşturmuştur. Bu derleme, akciğer kanseri tedavisindeimmünoterapi yaklaşımının göğüs hastalıkları başta olmak üzere tüm branşlarda multidisipliner farkındalığını artırmayı ve yönetimi hakkında bilgi sağlamayıamaçlayan ilk Türkçe derlemedir. Ayrıca bu derleme, KHDAK tedavisinde İKNİkullanımına ilişkin son klinik çalışmaların dikkat çekici sonuçlarını sunmasıaçısından önem teşkil etmektedir. İmmünoterapi kanser tedavisinde yeni bir dönem başlatmıştır ve İKNİ tedavisinin kendine özgü etki mekanizması yeni bazı advers olay grubunun ortaya çıkmasına nedenolmuştur, bunlar arasında pnömonitis özellikle önemlidir ve advers olaylar konusunda gerektiğinde hastaların ilgili uzmanlık dalları ilekonsülte edilmesi gerekmektedir. Akciğer kanserinde tedavi, hastanın özellikleri, histolojik özellikler, genetik durum göz önünde bulundurularak her bir hastaya özel planlanmalı ve akciğer kanserli bir hastanın tanısal değerlendirilmesi ve en uygun şekilde tedavisi içingöğüs hastalıkları, göğüs cerrahisi, tıbbi onkoloji, radyasyon onkolojisi, patoloji ve radyoloji uzmanlık dalları arasında işbirliği sağlanmalıdır. Bununla birlikte, aile hekimleri de akciğer kanserinin erken tanınmasında ve ayrıca hastalarını tütün bırakmayı teşvik ederekkanserin önlenmesinde önemli rol oynayabilirler. Ayrıca, toplumda farkındalık yaratmak ve erken tanı için akciğer kanseri yönündentarama çalışmaları yapmak hedeflenmelidir
Citation - WoS: 0
Citation - Scopus: 0
Amendments on "application of Mises Yield Criterion To Rotating Solid Disk Problem" by N. Aleksandrova [int. J. Eng. Sci. 51 (2012) 333-337]
(Pergamon-elsevier Science Ltd, 2012) Eraslan, Ahmet N.; Akis, Tolga; Civil Engineering
[No Abstract Available]
Citation - WoS: 202
Citation - Scopus: 283
Analysing Global Food Waste Problem: Pinpointing the Facts and Estimating the Energy Content
(de Gruyter Open Ltd, 2013) Melikoglu, Mehmet; Lin, Carol Sze Ki; Webb, Colin; Energy Systems Engineering
Food waste is a global problem. Each year food worth billions of dollars is wasted by the developed economies of the world. When food is wasted, the problem does not end at that point. More than 95% of the food waste ends at landfill sites, where converted into methane, carbon dioxide and other greenhouse gasses by anaerobic digestion. The impact of food waste to climate change is catastrophic. Food waste problem tends to increase in next 25 years due to economic and population growth mainly in Asian countries. In addition, when food wastes buried at landfill sites their energy content is lost. Although food waste is a huge problem, its global size and extent has recently become a hot topic in the academic community. This paper summarises the size of the global food waste problem together with the estimation of the amount of energy lost when food wastes dumped at landfill sites. Calculations in this study also revealed that energy lost at landfill sites equals to 43% of the delivered energy used for the preparation of foods in the US, 37% of the hydroelectric power generation of Japan, and more than 100% of the current annual renewable energy demand of UK industries.
Citation - WoS: 0
Citation - Scopus: 0
Antioxidant Activity of Micractinium Sp. (Chlorophyta) Extracts Against H2o2 Induced Oxidative Stress in Human Breast Adenocarcinoma Cells
(Nature Portfolio, 2025) Bulut, Onur; Kose, Iskin Engin; Sonmez, Cagla; Oktem, Huseyin Avni
Citation - WoS: 51
Citation - Scopus: 59
Application of Minimum Quantity Lubrication Techniques in Machining Process of Titanium Alloy for Sustainability: a Review
(Springer London Ltd, 2019) Osman, Khaled Ali; Unver, Hakki Ozgur; Seker, Ulvi
Recently, the manufacturing sector is increasingly keen to apply sustainability at all levels of sustainability from system to products and processes. At the processes level, cutting fluids (CFs) are among the most unsustainable materials and need to be addressed properly in accordance with three main and decisive aspects, also known as the triple bottom line: ecology, society, and economics. Minimum quantity lubrication (MQL) is a promising technique that minimizes the use of CFs, thus improving sustainability. This paper presents a review of the literature available on the use of the MQL technique during different machining processes involving titanium alloys (Ti-6Al-4V). To carry out the study, four search engines were used to focus on the most cited articles published over a span of 17years from 2000 to 2016. The performance and drawbacks are compiled for each eco-friendly technique: dry, MQL, and cryogenics with combinations of MQL and cryogenics, critically considering machining parameters such as cutting speed, feed rate, and output measures, namely surface roughness, tool life, and cutting temperature. After drawing conclusions from critical evaluation of research body, future research avenues in the field are proposed for the academics and industry.
Citation - WoS: 33
Citation - Scopus: 35
Aptamer Hybrid Nanocomplexes as Targeting Components for Antibiotic/Gene Delivery Systems and Diagnostics: a Review
(Dove Medical Press Ltd, 2020) Rabiee, Navid; Ahmadi, Sepideh; Arab, Zeynab; Bagherzadeh, Mojtaba; Safarkhani, Moein; Nasseri, Behzad; Tayebi, Lobat
With the passage of time and more advanced societies, there is a greater emergence and incidence of disease and necessity for improved treatments. In this respect, nowadays, aptamers, with their better efficiency at diagnosing and treating diseases than antibodies, are at the center of attention. Here, in this review, we first investigate aptamer function in various fields (such as the detection and remedy of pathogens, modification of nanoparticles, antibiotic delivery and gene delivery). Then, we present aptamer-conjugated nanocomplexes as the main and efficient factor in gene delivery. Finally, we focus on the targeted co-delivery of genes and drugs by nanocomplexes, as a new exciting approach for cancer treatment in the decades ahead to meet our growing societal needs.
Citation - WoS: 0
Citation - Scopus: 0
Artificial intelligence's impact on oral healthcare in terms of clinical outcomes: a bibliometric analysis
(Emerald Group Publishing Ltd, 2024) AlQaifi, Faten; Tengilimoglu, Dilaver; Aras, Ilknur Arslan
Purpose - This study provides a comprehensive overview of the impact of artificial intelligence (AI) applications on oral healthcare, focusing on clinical outcomes. Design/methodology/approach - A systematic approach was used to gather articles from databases such as Scopus, ScienceDirect, PubMed, Web of Science and Google Scholar from 2010 to 2024. The selection criteria included articles published in English, focusing solely on clinical applications of AI in dentistry. Articles such as conference proceedings, editorial material and personal opinions were excluded. The articles were analyzed and visualized using Rayyan software, Microsoft Excel and VOSviewer. Findings - Results indicate that 120 publications were authored by 58 scholars from 92 institutions across 29 countries, with a notable surge since 2018. This analysis showed the significant emphasis on the use of deep learning, demonstrating its high accuracy and performance in oral healthcare, often exceeding that of dentists. It also proved that even though AI is sometimes seen as an auxiliary tool, many studies revealed that AI has a performance near dental professionals' levels. Findings concluded that the majority of studies indicate that AI is generating better clinical outcomes in oral healthcare. Practical implications - This study provides dental professionals with insights on integrating AI for better diagnosis and treatment. Policymakers and healthcare institutions can use these findings to inform AI adoption and training strategies. Originality/value - It presents novel and valuable findings that can benefit various stakeholders by shedding light on the present scenario and potential future paths of AI integration in oral healthcare, contributing to its overall advancement.
Citation - WoS: 16
Citation - Scopus: 20
Assessing the Coverage of E-Health Services in Sub-Saharan Africa a Systematic Review and Analysis
(Georg Thieme verlag Kg, 2017) Adeloye, Davies; Adigun, Taiwo; Misra, Sanjay; Omoregbe, Nicholas; Computer Engineering
Background: E-Health has attracted growing interests globally. The relative lack of facilities, skills, funds and information on existing e-Health initiatives has affected progress on e-Health in Africa. Objectives: To review publicly available literature on e-Health in sub-Saharan Africa (sSA) towards providing information on existing and ongoing e-Health initiatives in the region. Methods: Searches of relevant literature were conducted on Medline, EMBASE and Global Health, with search dates set from 1990 to 2016. We included studies on e-Health initiatives (prototypes, designs, or completed projects) targeting population groups in sSA. Results: Our search returned 2322 hits, with 26 studies retained. Included studies were conducted in 14 countries across the four sub-regions in sSA (Central, East, South and West) and spreading over a 12-year period, 2002-2014. Six types of e-Health interventions were reported, with 17 studies (65%) based on telemedicine, followed by mHealth with 5 studies (19%). Other e-Health types include expert system, electronic medical records, e-mails, and online health module. Specific medical specialties covered include dermatology (19%), pathology (12%) and radiology (8%). Successes were 'widely reported' (representing 50% overall acceptance or positive feedbacks in a study) in 10 studies (38%). The prominent challenges reported were technical problems, poor inter net and connectivity, participants' selection biases, contextual issues, and lack of funds. Conclusion: E-Health is evolving in sSA, but with poorly published evidence. While we call for more quality research in the region, it is also important that population-wide policies and on-going e-Health initiatives are contextually feasible, acceptable, and sustainable.
Citation - WoS: 51
Citation - Scopus: 58
Atmospheric Pressure Plasma Surface Treatment of Polymers and Influence on Cell Cultivation
(Mdpi, 2021) Sasmazel, Hilal Turkoglu; Alazzawi, Marwa; Alsahib, Nabeel Kadim Abid; Metallurgical and Materials Engineering
Atmospheric plasma treatment is an effective and economical surface treatment technique. The main advantage of this technique is that the bulk properties of the material remain unchanged while the surface properties and biocompatibility are enhanced. Polymers are used in many biomedical applications; such as implants, because of their variable bulk properties. On the other hand, their surface properties are inadequate which demands certain surface treatments including atmospheric pressure plasma treatment. In biomedical applications, surface treatment is important to promote good cell adhesion, proliferation, and growth. This article aim is to give an overview of different atmospheric pressure plasma treatments of polymer surface, and their influence on cell-material interaction with different cell lines.
Citation - WoS: 4
Citation - Scopus: 4
Author's Reply To "comments on 'modified Criterion for Global Asymptotic Stability of Fixed-Point State-Space Digital Filters Using Two's Complement Arithmetic [automatica 46 (2010) 475-478]'"
(Pergamon-elsevier Science Ltd, 2010) Singh, Vimal; Department of Mechatronics Engineering
[No Abstract Available]
Citation - WoS: 1
Citation - Scopus: 2
Bias in human data: A feedback from social sciences
(Wiley Periodicals, inc, 2023) Takan, Savas; Ergun, Duygu; Yaman, Sinem Getir; Kilincceker, Onur
The fairness of human-related software has become critical with its widespread use in our daily lives, where life-changing decisions are made. However, with the use of these systems, many erroneous results emerged. Technologies have started to be developed to tackle unexpected results. As for the solution to the issue, companies generally focus on algorithm-oriented errors. The utilized solutions usually only work in some algorithms. Because the cause of the problem is not just the algorithm; it is also the data itself. For instance, deep learning cannot establish the cause-effect relationship quickly. In addition, the boundaries between statistical or heuristic algorithms are unclear. The algorithm's fairness may vary depending on the data related to context. From this point of view, our article focuses on how the data should be, which is not a matter of statistics. In this direction, the picture in question has been revealed through a scenario specific to "vulnerable and disadvantaged" groups, which is one of the most fundamental problems today. With the joint contribution of computer science and social sciences, it aims to predict the possible social dangers that may arise from artificial intelligence algorithms using the clues obtained in this study. To highlight the potential social and mass problems caused by data, Gerbner's "cultivation theory" is reinterpreted. To this end, we conduct an experimental evaluation on popular algorithms and their data sets, such as Word2Vec, GloVe, and ELMO. The article stresses the importance of a holistic approach combining the algorithm, data, and an interdisciplinary assessment.This article is categorized under:Algorithmic Development > Statistics
Citation - WoS: 0
Citation - Scopus: 0
Bilateral adrenal haemorrhage after blunt abdominal trauma
(Ma Healthcare Ltd, 2023) Guvendi, Bulent; Koksal, Ali; Gozgec, Elif; Ogul, Hayri; Kantarci, Mecit; Medical Imaging Techniques Program
[No Abstract Available]
Citation - WoS: 5
Binary Alloy Clusters: Structures and Electronic Properties
(Amer Scientific Publishers, 2014) Pekoez, Rengin; Oymak, Hueseyin; Erkoc, Akir; Electrical-Electronics Engineering
Synthesis, characterization, physics, and chemistry of nanoclusters have been the focus of intense attention for the last two decades. Also, their unique statues that they are between molecule and bulk material is the central reason for the theoretical researcher to understand the transition from atom to cluster/molecule and then to solid state. In this review we restrict ourselves to the recent advances in the structural and electronic properties of binary alloy clusters. This type of clusters is particularly of importance thanks to their very availability for being tuned, by changing their sizes, according to any special needs. A brief summary of the classification of clusters as well as the experimental techniques and theoretical methods to study them, and the possible applications of alloy clusters are given in the introduction part. Several binary alloy cluster types, including semiconductor, alkali and transition metal, oxide, and ionic binary alloy clusters, are widely reviewed considering extensively the most recent articles.
Citation - WoS: 19
Citation - Scopus: 22
Bioprinting and biomaterials for dental alveolar tissue regeneration
(Frontiers Media Sa, 2023) Ostrovidov, Serge; Ramalingam, Murugan; Bae, Hojae; Orive, Gorka; Fujie, Toshinori; Shi, Xuetao; Kaji, Hirokazu
Three dimensional (3D) bioprinting is a powerful tool, that was recently applied to tissue engineering. This technique allows the precise deposition of cells encapsulated in supportive bioinks to fabricate complex scaffolds, which are used to repair targeted tissues. Here, we review the recent developments in the application of 3D bioprinting to dental tissue engineering. These tissues, including teeth, periodontal ligament, alveolar bones, and dental pulp, present cell types and mechanical properties with great heterogeneity, which is challenging to reproduce in vitro. After highlighting the different bioprinting methods used in regenerative dentistry, we reviewed the great variety of bioink formulations and their effects on cells, which have been established to support the development of these tissues. We discussed the different advances achieved in the fabrication of each dental tissue to provide an overview of the current state of the methods. We conclude with the remaining challenges and future needs.
Citation - WoS: 0
Can Military Zones Be an Opportunity for Revitalizing Ankara's Green Belt and Upper Scale Urban Planning?
(Kare Publ, 2016) Sahin, Savas Zafer; Department of Public Administration and Political Science
[No Abstract Available]
Citation - WoS: 0
Capitalism Hits the Fan: the Global Economic Meltdown and What To Do About It
(Akademiai Kiado Zrt, 2014) Temel, Bulent; Temel, Bülent Azmi; Temel, Bülent Azmi; Department of Business; Department of Business
[No Abstract Available]
Citation - WoS: 0
Citation - Scopus: 0
The Cardiovascular Scamdemic: The Epidemic Spread of Cardiovascular Treatment Scams and Misinformation
(Baycinar Medical Publ-baycinar Tibbi Yayincilik, 2024) Demirkilic, Ufuk; Tosun, Burcu
Recently, some cardiovascular surgeons have been increasingly using social media for marketing, often employing misleading terminology. This trend, which we termed the "cardiovascular scamdemic," involves the widespread dissemination of deceptive advertisements for cardiovascular treatments, resembling an epidemic. Exposure to such misinformation not only endangers patients, who naturally rely on information from professional sources, but also erodes public trust in medical ethics and scientific integrity. Additionally, it contributes to treatment refusal and adverse health outcomes. The lack of comprehensive global regulations addressing these issues highlights the urgent need for more effective enforcement measures.

Browse

Browsing WoS by Publication Category "Diğer"