Browsing by Author "Turkoglu Sasmazel,H."

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Citation - Scopus: 1
Materials and Processes for Treatment of Microbiological Pollution in Water
(Springer, 2021) Alazzawi,M.; Turkoglu Sasmazel,H.
Clean and safe water is vital for the life and health of human beings. However, there are still millions of people around the world with inadequate clean water sources. Microbiological pollution is one of the most concerned water pollutants and is the crucial cause of waterborne diseases like diarrhea, resulting in about two million deaths annually due to severe dehydration (WHO in Guidelines for drinking-water quality. Incorporating the first addendum, WHO, Geneva, 2017). It is critical to develop methods using advanced materials and process to mitigate contaminants from water resources. Production of safe water usually involves disinfection and decontamination processes. Conventional disinfection process, such as chlorination, is challenged by the formation of disinfection by-products. Furthermore, the presence of emerging pathogenic, that resist conventional water treatment techniques, raised the crucial necessity for emerging materials and techniques for treating water from microbiological pollution (Shannon et al. in Nature 452:301–310, 2008). This chapter describes bacterial, viral, and protozoal microbiological pollution in water supplies and the application of emerging materials and techniques to eliminate such contaminations. © 2021, Springer Nature Switzerland AG.
Poly(ε-caprolactone)/Chitosan Nanostructures for Cell Cultivation
(Springer, 2020) Turkoglu Sasmazel,H.
Hybridization of synthetic poly (ε-caprolactone) (PCL) and natural chitosan polymers to develop PCL/chitosan core-shell nanostructures for cell cultivation was aimed in this study. Coaxial electrospinning method was used for the fabrication of the nanostructures. The characterizations of the samples were done by X-ray photoelectron spectroscopy (XPS) analyses and mechanical tests. XPS analysis of the PCL/chitosan core-shell structures exhibited the characteristic peaks of PCL and chitosan polymers. The cell culture studies, MTT assay and Confocal Laser Scanning Microscopy (CLSM), carried out with L929 ATCC CCL-1 mouse fibroblast cell line, proved the biocompatibility of all materials. The cell viability on the hybrid nanostructures was ~two times better then on tissue culture polystyrene (TCPS) because of its three dimensional (3D) extracellular matrix (ECM)-like structure compared to 2D flat surface of commercially cell compatible TCPS. The performance was ~two times and ~ten times better compared to single PCL and single chitosan, respectively, even though both fabricated similarly by electrospinning as non-woven fibrous structures, because were either too hydrophobic or too hydrophilic to maintain cell attachment points. © Springer Nature B.V. 2020.