Production of the novel fibrous structure of poly(ε-caprolactone)/tri-calcium phosphate/hexagonal boron nitride composites for bone tissue engineering

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Date

2018

Authors

Ozbek, Burak
Erdogan, Barkin
Ekren, Nazmi
Oktar, Faik Nuzhet
Akyol, Sibel
Ben-Nissan, Besim
Gunduz, Oguzhan

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Australian Ceramic Society

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Abstract

Nanofibrous composites of the poly(epsilon-caprolactone) (PCL), tricalcium phosphate (TCP), and hexagonal boron nitride (h-BN) with different compositions were manufactured by using an economical and non-complicated method called electrospinning. Produced fibrous structures showed no bead formation and had a clean surface. Characterization of the composites showed that particles were successfully mixed with polymer phase. High cell activity of SaOS-2 cells on the composites was observed with SEM images. In addition, fibrous scaffolds are biocompatible with human bone tissue and are highly degradable.

Description

Gunduz, Oguzhan/0000-0002-9427-7574; Ozbek, Burak/0000-0003-2133-001X; Ben-Nissan, Besim/0000-0003-0433-3593; Ekren, Nazmi/0000-0003-3530-9262; Gunduz, Oguzhan/0000-0002-4926-6489; Turkoglu Sasmazel, Hilal/0000-0002-0254-4541

Keywords

Biopolymers, Biofibers, Biomaterials, Poly(epsilon-caprolactone), Composites

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12

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Q2

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Q2

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Volume

54

Issue

2

Start Page

251

End Page

260

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