Gülen, Merter

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Profile URL
https://hdl.handle.net/20.500.14411/7128
Name Variants
Merter, Gülen
M.,Gülen
Merter, Gulen
M.,Gulen
Gülen,M.
Gulen M.
M., Gulen
Gulen,M.
G., Merter
G.,Merter
Gulen, M
Gulen, Merter
Gülen, Merter
M., Gülen
Job Title
Doktor Öğretim Üyesi
Email Address
merter.gulen@atilim.edu.tr
Main Affiliation
Surgical Sciences
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Website
ORCID ID
Scopus Author ID
40261432600
Turkish CoHE Profile ID
Google Scholar ID
WoS Researcher ID
CRX-2118-2022

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10

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7

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0

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9

Scopus Citation Count

8

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0

WoS Citations per Publication

0.90

Scopus Citations per Publication

0.80

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5

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0

JournalCount
Bratislava Medical Journal2
Frontiers in Surgery1
Journal of medicine and palliative care (Online)1
Journal of the College of Physicians and Surgeons Pakistan1
Minerals, Metals and Materials Series – 11th International Symposium on High-Temperature Metallurgical Processing, held in conjunction with the 149th Annual Meeting and Exhibition, TMS 2020 – San Diego, CA – 2367691
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Subject: Alkaline Phosphatase

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    Article
    Importance of Alkaline Phosphatase as a Predictor of Transient Hypoparathyroidism After Parathyroidectomy
    (Springernature, 2025) Gulen, Merter; Emral, Ahmet Cihangir; Sariyildiz, Gulcin Turkmen
    BackgroundThere are insufficient studies that have investigated the relationship between temporary hypoparathyroidism (hypoPTH) and the preoperative serum alkaline phosphatase (ALP) level in patients with no renal function disorder who have undergone isolated parathyroidectomy. The aim of this study was to determine whether or not the preoperative serum ALP level could be a marker which could predict the development of postoperative temporary hypoPTH. MethodsThis cross-sectional study included 158 patients aged > 18 years who were diagnosed with primary hyperparathyroidism (PHPT) between 2017 and 2022. The demographic data of the patients were retrieved from the hospital records. The patients were separated into two groups according to the serum calcium level after the parathyroidectomy, as the normal group and the temporary hypoPTH group. The determinants of temporary hypoPTH developing after parathyroidectomy in PHPT patients were investigated using multivariate logistic regression analysis. ResultsTemporary hypoPTH was determined in 25.3% of patients. The mean age and 25-O-HD level were determined to be lower in the patients who developed temporary hypoPTH compared to those who did not. The preoperative serum ALP, parathormone, and 24-h urine calcium levels were determined to be higher in the cases that developed temporary hypoPTH. As a result of the regression analysis, only the serum ALP level was determined to be an independent risk factor predicting the development of temporary hypoPTH (p: 0.005, OR: 1.021). In the ROC analysis, when a cutoff value of 119.5 pg/mL was taken for ALP, it was determined to have 73% sensitivity and 72% specificity for the prediction of the development of temporary hypoPTH. ConclusionsThe most appropriate treatment for symptomatic PHPT patients selected with positive imaging is minimally invasive parathyroidectomy. The most important postoperative complications are hypocalcemia and hypoPTH. The preoperative serum ALP level may be helpful in determining patients at risk of developing temporary hypoPTH following parathyroidectomy.