Can, Nalan

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https://hdl.handle.net/20.500.14411/7154
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N., Can
N.,Can
Nalan, Can
Can, N.
C.,Nalan
Can, Nalan
C., Nalan
Can,N.
Job Title
Doktor Öğretim Üyesi
Email Address
nalan.can@atilim.edu.tr
Main Affiliation
Internal Medical Sciences
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Scopus Author ID
24066443100
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WoS Researcher ID
EPE-9418-2022

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NO POVERTY1
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GOOD HEALTH AND WELL-BEING3
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CLEAN WATER AND SANITATION6
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AFFORDABLE AND CLEAN ENERGY7
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DECENT WORK AND ECONOMIC GROWTH8
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INDUSTRY, INNOVATION AND INFRASTRUCTURE9
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3

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36

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2

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2

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WoS Citation Count

20

Scopus Citation Count

20

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10.00

Scopus Citations per Publication

10.00

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1

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International Journal of General Medicine2
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    Article
    Citation - Scopus: 20
    Laboratory and Imaging Evaluation of Cardiac Involvement in Patients With Post-Acute Covid-19
    (Dove Medical Press Ltd, 2021) Sarıçam,E.; Dursun,A.D.; Sarıyıldız,G.T.; Can,N.; Bozkurt,E.; Gönüllü,U.; Ünlü,M.
    Background: In the post-acute COVID-19 syndrome, many patients suffer from palpitations, effort-associated fatigue, and even sudden death. The mechanism of heart involvement in this syndrome is uncertain. The main purpose of the study was to identify possible cardiac involvement causes in patients with post-acute COVID-19 by using biomarkers such as NT-proBNP and nitric oxide (NO) and cardiac imaging modalities. Methods: In this cross-sectional study, a total of 105 participants were included according to the existence of symptoms, and 40 of these participants were asymptomatic patients. The ages of the participants ranged from 20 to 50 years. All patients were healthy before COVID-19. The symptoms were defined as palpitations and/or fatigue association with exercise in post-acute COVID-19 term. The comparison of the two groups was made by using biochemical parameters (NT-proBNP, Troponin I, NO) and imaging techniques (echocardiography, cardiovascular magnetic resonance (CMR) and cardiac positron emission tomography (PET)). Results: The symptomatic patients had higher NT-proBNP levels compared with asymptomatic patients (132.30±35.15; 76.86±16.79, respectively; p < 0.001). Interestingly, the symptomatic patients had lower NO levels than asymptomatic patients (9.20±3.08; 16.15 ±6.02, respectively; p < 0.001). Echocardiography and CMR were normal. However, we found regional increased 18F-FDG uptake on cardiac PET to be compatible with myocardial fatigue. Conclusion: We found elevated NT-proNBP levels, low serum NO levels, and increased 18F-FDG uptake on cardiac PET in post-acute COVID syndrome. Cardiac PET could replace or be added to CMR for detecting subtle subacute/chronic myocarditis. The follow-up of patients with post-acute COVID-19 could target the possibility of risk of heart failure. © 2021 Sarıçam et al. This work is published and licensed by Dove Medical Press Limited.