Aydın, Canset

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A.,Canset
C., Aydın
Canset, Aydın
C.,Aydin
C., Aydin
Aydin,C.
Aydın,C.
Canset, Aydin
Aydin, Canset
Aydin C.
Aydın, Canset
A., Canset
C.,Aydın
Aydin,C.C.
Job Title
Doktor Öğretim Üyesi
Email Address
canset.aydin@atilim.edu.tr
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Surgical Sciences
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27

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122

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JournalCount
IEEE International Symposium on Personal, Indoor and Mobile Radio Communications, PIMRC -- 18th Annual IEEE International Symposium on Personal, Indoor and Mobile Radio Communications, PIMRC'07 -- 3 September 2007 through 7 September 2007 -- Athens -- 721052
Acta Medica1
American Journal of Otolaryngology1
Cell and Tissue Banking1
ENT Updates1
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Now showing 1 - 8 of 8
  • Article
    Citation - Scopus: 2
    The Distribution of Geriatric Problems in Otolaryngology and Their Alteration From Young Adults
    (Wolters Kluwer Medknow Publications, 2021) Onay, O.; Aydin, C.
    Background: Many changes occur in human physiology with aging, and as expected complaints of geriatric patients differ from the other age groups in population. Aims: The objective of the study was to investigate the common complaints of geriatric patients attending to an otolaryngology clinic (ENT clinic), and to compare their complaints with the 18-65 years aged patients'. Materials and Methods: A total number of 41888 adult patients who visited the ENT clinic from 2015 to 2018 were retrospectively investigated. Patient complaints were scanned, and subcategorized as five groups (otologic/rhinologic/head and neck/ others/ neoplasias) and all data were evaluated. Results: Forty-one thousand, eight hundred and eighty-eight patients were included in the study, and 3946 of them were geriatric patients. The most frequent problem was otologic problems, followed by rhinologic problems among geriatric patients. However, rhinologic problems were the major complaint among the 18-65-year-old patients. A comparison of all the individual complaints bringing the geriatric patients to the ENT clinic revealed the three most frequent complaints: 1. hearing loss, 2. balance disorders, and 3. common cold. However, the three major complaints beyond nongeriatric adults were 1. tonsillopharyngeal disease, 2. common cold, and 3. inflammatory and infectious diseases of the sinuses, and these differences were statistically significant (P = 0.001*). Conclusion: It was found in this study that the five most frequently reported complaints of geriatric patients when applying to an ENT clinic are hearing loss, loss of balance, common cold, cerumen, and tonsillopharyngeal diseases. Unlike from nongeriatric population, otologic problems (most commonly hearing loss) were the essential ENT clinic complaints of geriatric patients.
  • Article
    Citation - WoS: 11
    Citation - Scopus: 15
    Comparison of Cervical and Ocular Vestibular-Evoked Myogenic Potential Responses Between Tone Burst Versus Chirp Stimulation
    (Springer, 2021) Aydin, Canset; Onay, Ovsen; Tezcan, Elif Ilkay; Askar, Zuhal; Ozdek, Ali
    Purpose To compare the effectiveness of chirp and tone burst stimuli in oVEMP and cVEMP testing for healthy adults Methods This study was conducted in 56 healthy volunteers (112 ears). Ocular and cervical VEMP (oVEMP, cVEMP) tests were performed for each participant using tone burst and chirp stimuli. VEMP response rates, latency of each peak (p1-n1, n1-p1), peak to peak amplitude (p1-n1 amplitude and n1-p1 amplitude), and rectified amplitudes were measured and compared between these two different stimuli. Results VEMP response rates with chirp stimuli are higher than the tone burst stimuli for both cVEMP and oVEMP tests (The difference was statistically significant for oVEMP, p = 0.001). Chirp stimuli have higher p1n1 amplitude and rectified amplitude and shorter p1and n1 latency then tone burst stimuli for cVEMP (p = 0.015, p = 0.007, p < 0.001, p < 0.001, respectively). Chirp stimuli also have higher n1p1 amplitude and shorter n1and p1 latency then tone burst stimuli for oVEMP (p = 0.006, p < 0.001, p < 0.001, respectively). Conclusion The present findings show that the chirp stimulus triggers earlier VEMP responses with higher amplitudes than the tone burst stimulus during cVEMP and oVEMP testing. VEMP response rate with chirp stimulus is also higher than the tone burst. Therefore chirp stimulus can be used in VEMP testing as effectively as, if not more than, tone burst stimulus in clinical practice.
  • Article
    Association of Cognitive Status, Anxiety and Depression With Hearing Loss in the Elderly
    (2024) Gülmez, Mehmet İhsan; Aydın, Canset
    Objective: Hearing loss is an important problem that is common among older people. Dementia can be defined as a group of disorders that adversely affect memory, thinking function and the ability to perform daily activities. Hearing loss leads to poor quality of life due to loneliness, social isolation, anxiety and susceptibility to depression. Hearing aids are the primary tool used in the management of hearing loss. In this study, we aimed to compare participants with and without hearing loss in terms of cognitive status, depression and anxiety, and to assess the effect of hearing aid use on this process. Method: Between June 2023 and June 2024, 608 patients over the age of 50 who registered at the psychiatric outpatient clinic of Hatay Training and Research Hospital were included in the study. Participants were enrolled if they presented to the Psychiatry outpatient clinic during the selected time interval, were over 50 years of age and agreed to participate in the study. Participants' demographic information, educational status, social information, hearing aid use, minimental score, Beck anxiety score, and geriatric depression score were recorded. Results: When comparing patients with and without hearing loss, statistically significant differences were observed on the Minimental Test, Beck Anxiety Score and Geriatric Depression Score. Conclusion: In this study, a statistically significant relationship was found between hearing loss and cognitive status, depression and anxiety, and it was suggested that the use of hearing aids may be beneficial in terms of preventing the development or slowing the progression of these pathologies.
  • Article
    Citation - WoS: 1
    Citation - Scopus: 1
    A Retrospective Analysis of Patients Who Underwent Tracheal Resection and End-To Anastomosis Surgery for Benign Tracheal Stenosis, Over a 10-Year Period
    (W B Saunders Co-elsevier inc, 2024) Gulmez, M. Ihsan; Kutay, Funda; Aydin, Canset; Akoglu, Ertap; Okuyucu, Semsettin
    Introduction: Laryngotracheal stenosis encompasses a diverse range of diagnoses, encompassing complete or partial narrowing of various subgroups of the upper airways, including the laryngeal structures and trachea, due to pathological scar formation. This increasingly prevalent pathology is of significant importance due to its potential for life-threatening consequences. Among the defined treatment modalities, tracheal resection and endto-side anastomosis remain a valuable therapeutic alternative in appropriate indications. Objective: The objective of this study was to retrospectively evaluate the outcomes of patients who underwent tracheal resection and end-to-end anastomosis at our clinic over the past decade. Material & method: All patients who underwent tracheal resection and end-to-end anastomosis surgery for benign tracheal stenosis at the Department of Otolaryngology, Mustafa Kemal University Hospital between 2013 and 2023 were included in the study. The diagnosis of tracheal stenosis was based on endoscopic examination and computed tomography results. Interventions without postoperative symptoms and without the need for additional surgical intervention were considered successful. The study was approved by Hatay Mustafa Kemal University Ethics Committee with decision number 2023/27. Results: A total of 29 patients were included in the study. The mean age of the patients was 26.48 years. 3 patients (10.35 %) had a comorbidity. In all patients orotracheal intubation or intubation and tracheotomy was the aetiological cause. There were no intraoperative complications. In the postoperative period, wound infection was observed in 3 patients (10.35 %) and subcutaneous emphysema in 2 patients (6.9 %). In 1 patient (3.45 %) recurrent respiratory distress was observed, restenosis was considered and tracheotomy was performed. Our complication rate was 20.69 %. When all patients were evaluated at the end of the postoperative follow-up period, the surgical success rate was calculated to be 96.55 %. Conclusion: With a surgical success rate of 96.55 % and a low complication rate in our study, we believe, in parallel with previous studies, that open surgery is a reliable, physiologically appropriate and successful method among the current treatments for tracheal stenosis.
  • Article
    Citation - WoS: 6
    Citation - Scopus: 8
    Endonasal Choanal Atresia Repair; Evaluating the Surgical Results of 58 Cases
    (Turkish J Pediatrics, 2021) Bajin, Munir Demir; Onay, Ovsen; Gunaydin, Riza Onder; Unal, Omer Faruk; Yucel, Omer Taskin; Akyol, Umut; Aydin, Canset
    Background. Choanal atresia is the most common congenital nasal anomaly, with an incidence of 1:5000-1:8000 live births. Atresia can be seen as membraneous, bony or mixed type. When it is bilateral, it is accepted life-threatening, therefore bilateral atresia necessitates immediate intervention. Diagnosis is confirmed by endoscopic examination and computed tomography. The absolute treatment is surgical, and different approaches have been proposed. Methods. Herein, we describe our 15-year experience in the treatment of 58 patients of congenital choanal atresia with transnasal endoscopic approach, and we compare the efficacy of placement of an intranasal stent and applying mitomycin while endoscopic microsurgical repair. Results. The study included 41 female patients (71%) and 17 male patients (29%) with congenital CA. The mean age was 3 years ranging from 10 days to 16 years. The atretic plate was bilateral in 24 patients (41%) and unilateral in 34 (59%). The most common atresia type was the mixed type with 29 patients (50%). A total of 17 patients (29%) required postoperative revision(s). Postoperative revisions were more frequent among patients with bilateral CA (50%), and with mixed CA (31%). Stenting was used additionally by surgical correction for 10 patients. After stenting, fibrosis and restenosis was seen in 7 patients (79%). Mitomycin C was applied peroperatively in 8 patients. Restenosis after mitomycin application was seen in 4 patients (50%). Conclusions. By our experience, endoscopic microsurgical repair of atresia proved to be an effective and safe procedure, results compared with adjuvant treatment modalities like stent or mitomycin C use, was not better. Restenosis was the major problem seen after surgical correction.
  • Article
    Citation - WoS: 9
    Citation - Scopus: 11
    Human Laryngeal Squamous Cell Carcinoma Cell Line Release of Endogenous Anandamide and 2-Arachidonoylglycerol, and Their Antiproliferative Effect Via Exogenous Supplementation: an in Vitro Study
    (Springer, 2022) Onay, Ovsen; Kose, Sevil; Suslu, Nilda; Korkusuz, Petek; Nemutlu, Emirhan; Aydin, Canset; Hosal, Sefik
    The level of the major endocannabinoids anandamide (AEA) and 2-arachidonoylglycerol (2-AG) are altered in several types of carcinomas, and are known to regulate tumor growth. Thusly, this study hypothesized that the HEp-2 human laryngeal squamous cell carcinoma (LSCC) cell line releases AEA and 2-AG, and aimed to determine if their exogenous supplementation has an anti-proliferative effect in vitro. In this in vitro observational study a commercial human LSCC cell line (HEp-2) was used to test for endogenous AEA and 2-AG release via liquid chromatography-tandem mass spectrometry (LC-MS/MS). The anti-proliferative effect of AEA and 2-AG supplementation was evaluated via WST-1 proliferation assay. It was observed that the HEp-2 LSCC cell line released AEA and 2-AG; the median quantity of AEA released was 15.69 ng mL(-1) (range: 14.55-15.95 ng mL(-1)) and the median quantity of 2-AG released was 2.72 ng (-1) (range: 2.67-2.74 ng mL(-1)). Additionally, both AEA and 2-AG exhibited an anti-proliferative effect. The anti-proliferative effect of 2-AG was stronger than that of AEA. These findings suggest that AEA might function via a CB1 receptor-independent pathway and that 2-AG might function via a CB2-dependent pathway. The present findings show that the HEp-2 LSCC cell line releases the major endocannabinoids AEA and 2-AG, and that their supplementation inhibits tumor cell proliferation in vitro. Thus, cannabinoid ligands might represent novel drug candidates for laryngeal cancers, although functional in vivo studies are required in order to validate their potency.
  • Article
    Diagnostic Value of Thyroid Physical Examination in the Elderly and Comparison with Ultrasonography
    (UK Scientific Publishing Ltd, 2025) Gulmez, Mehmet Ihsan; Aydin, Canset
    This study is part of the health project called "Health screening for the elderly in Ankara" for patients aged 65 and over, with 1200 participants. Patients with missing laboratory tests (n = 59), movement disorders and/or bedridden (n = 54) were excluded from the study. PE was performed by a geriatrician or an ear, nose, and throat surgeon, and ultrasonographic evaluation was performed by a radiologist. PE and USG findings were compared. We aimed to investigate the diagnostic accuracy of physical examination (PE) of the thyroid gland (TG) in patients over 65 years of age and to assess the reliability by comparing PE with ultrasonographic (USG) examination. The median age of the patients participating in the study was 71.17. When the differences between thyroid nodules (TN), the number of TN size, and goiter detection were compared in terms of PE and USG, all values were statistically signifi- cant, and P values were < 0.001. The sensitivity of PE of TG was calculated as 31.0%. In our study, the sensitivity of PE of TG in terms of TN and goiter was found to below. The diagnostic accuracy of PE of TG is low, and therefore, its impact on clinical decision-making is limited. Furthermore, detected nodules rarely progress to clinically relevant disease, leading to overdiagnosis and overtreatment. Especially in groups at risk for nodules and malignancy, PE must be combined with imaging methods and, if necessary, pathological examination, even if nodules or goiter are not palpable in PE.
  • Article
    Premenstrual Syndrome as a Sleep Disturbing Factor: A CrossSectional Study
    (2021) Önay, Övsen; Aydın, Canset
    Objective: To evaluate the lifestyle factors possibly related with premenstrual syndrome which were body mass index, coffee intake, smoking, regular physical exercise, and alcohol consumption, and investigate the impact of these lifestyle factors and premenstrual syndrome on sleep quality. Methods and Methods: This cross-sectional study included 265 participants, and all applied Pittsburgh Sleep Quality Index and Premenstrual Syndrome Scale questionnaires. Results: The prevalence of premenstrual syndrome among the participants was 57% (n:150). Participants with premenstrual syndrome had shorter total sleep time (p:0.001). Also, they needed longer time to fall asleep (p:0.001). The Pittsburgh Sleep Quality Index scores of the participants with premenstrual syndrome were higher than those without premenstrual syndorme (p<0.001), indicating poor sleep quality. It was observed that the participants with premenstrual syndrome had more coffee intake (p:0.040) and more regular physical activity (p:0.009), which were risk factors of premenstrual syndrome. premenstrual syndrome positivity was associated with increased poor sleep quality in both univariate and multivariate analyses (OR:5.93 95% CI: 3.46- 10.15, p<0.001; OR:5.61 95% CI: 3.19-9.88, p<0.001, respectively). The remaining variables, which were risk factors of premenstrual syndrome, didn’t have any statistically significant association with sleep quality. Conclusion: The important relation between premenstrual syndrome and sleep quality is highlighted. Relief of premenstrual syndrome complaints may lead to better sleep quality and enhancement of quality of life for a woman.