Güntaş, Gülcan

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Guntas, Gulcan
Güntaş, Gülcan
G.,Gülcan
G., Guntas
Guntas,G.
G.,Guntas
G., Gulcan
G.,Güntaş
Gülcan, Güntaş
G.,Gulcan
Güntaş,G.
Gulcan, Guntas
Job Title
Profesör Doktor
Email Address
gulcan.guntas@atilim.edu.tr
Main Affiliation
Basic Sciences
Status
Former Staff
Website
ORCID ID
Scopus Author ID
Turkish CoHE Profile ID
Google Scholar ID
WoS Researcher ID

Sustainable Development Goals

SDG data is not available
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Scholarly Output

2

Articles

2

Views / Downloads

7/0

Supervised MSc Theses

0

Supervised PhD Theses

0

WoS Citation Count

6

Scopus Citation Count

7

WoS h-index

1

Scopus h-index

1

Patents

0

Projects

0

WoS Citations per Publication

3.00

Scopus Citations per Publication

3.50

Open Access Source

1

Supervised Theses

0

Google Analytics Visitor Traffic

JournalCount
Frontiers in Cardiovascular Medicine1
Minerva Dental and Oral Science1
Current Page: 1 / 1

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Scholarly Output Search Results

Now showing 1 - 2 of 2
  • Article
    Citation - WoS: 6
    Citation - Scopus: 6
    Quantitative Lipidomic Analysis of Takotsubo Syndrome Patients' Serum
    (Frontiers Media Sa, 2022) Karnati, Srikanth; Guntas, Gulcan; Rajendran, Ranjithkumar; Shityakov, Sergey; Hoering, Marcus; Liebisch, Gerhard; Foerster, Carola Y.
    Takotsubo syndrome (TTS), also known as the transient left ventricular apical ballooning syndrome, is in contemporary times known as novel acute cardiac syndrome. It is characterized by transient left ventricular apical akinesis and hyperkinesis of the basal left ventricular portions. Although the precise etiology of TTS is unknown, events like the sudden release of stress hormones, such as the catecholamines and the increased inflammatory status might be plausible causes leading to the cardiovascular pathologies. Recent studies have highlighted that an imbalance in lipid accumulation might promote a deviant immune response as observed in TTS. However, there is no information on comprehensive profiling of serum lipids of TTS patients. Therefore, we investigated a detailed quantitative lipid analysis of TTS patients using ES-MSI. Our results showed significant differences in the majority of lipid species composition in the TTS patients compared to the control group. Furthermore, the computational analyses presented was able to link the altered lipids to the pro-inflammatory cytokines and disseminate possible mechanistic pathways involving TNF alpha and IL-6. Taken together, our study provides an extensive quantitative lipidome of TTS patients, which may provide a valuable Pre-diagnostic tool. This would facilitate the elucidation of the underlying mechanisms of the disease and to prevent the development of TTS in the future.
  • Article
    Citation - Scopus: 1
    Serum Clusterin Levels Are Not Associated With Chronic Spontaneous Urticaria Regardless of Serum Lipids
    (Edizioni Minerva Medica, 2022) Vurgun,E.; Memet,B.; Etikan,P.; Guntas,G.; Kocaturk,E.
    BACKGROUND: Clusterin is related to immunity and inflammation via regulation of complement activation and bidirectional regulation, and by major proinflammatory cytokines. Clusterin levels have been the subject of a few research both in patients with hyperlipidemia and those with chronic spontaneous urticaria (CSU) separately. The aims of this study were to evaluate the levels of clusterin levels and serum lipids and the relationships between them in patients with CSU. METHODS: Fifty patients with CSU and 30 healthy controls were enrolled into the study. The activity of urticaria of the patients was determined by urticaria activity score (UAS7). Serum clusterin, total cholesterol, HDL, LDL and triglyceride levels of the participants were measured and compared. The relationships between UAS, lipids and clusterin were examined. RESULTS: There was no difference in clusterin levels between CSU patients and controls. Clusterin level was not related to activity of urticaria. Clusterin levels were not correlated with any of lipid parameters neither in CSU patients nor in controls. CONCLUSIONS: Findings of this study show that clusterin levels do not change due to CSU. Serum clusterin levels cannot be used as a diagnostic or a disease activity marker in CSU patients, regardless of the lipid profile. © 2022 EDIZIONI MINERVA MEDICA.