Önen, Selin

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Profile URL
https://hdl.handle.net/20.500.14411/8366
Name Variants
Selin, Önen
Önen,S.
Önen, Selin
O., Selin
Selin, Onen
S.,Önen
O.,Selin
S.,Onen
Onen,S.
Ö.,Selin
Onen, Selin
S., Onen
Job Title
Araştırma Görevlisi
Email Address
selin.onen@atilim.edu.tr
Main Affiliation
Basic Sciences
Status
Former Staff
Website
ORCID ID
Scopus Author ID
Turkish CoHE Profile ID
Google Scholar ID
WoS Researcher ID

Sustainable Development Goals

2

ZERO HUNGER
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0

Research Products

14

LIFE BELOW WATER
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0

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17

PARTNERSHIPS FOR THE GOALS
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0

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5

GENDER EQUALITY
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0

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16

PEACE, JUSTICE AND STRONG INSTITUTIONS
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0

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8

DECENT WORK AND ECONOMIC GROWTH
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0

Research Products

4

QUALITY EDUCATION
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0

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6

CLEAN WATER AND SANITATION
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1

Research Products

7

AFFORDABLE AND CLEAN ENERGY
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0

Research Products

10

REDUCED INEQUALITIES
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0

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11

SUSTAINABLE CITIES AND COMMUNITIES
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1

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9

INDUSTRY, INNOVATION AND INFRASTRUCTURE
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1

NO POVERTY
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3

GOOD HEALTH AND WELL-BEING
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4

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12

RESPONSIBLE CONSUMPTION AND PRODUCTION
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0

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13

CLIMATE ACTION
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15

LIFE ON LAND
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Scholarly Output

11

Articles

7

Views / Downloads

1/0

Supervised MSc Theses

0

Supervised PhD Theses

0

WoS Citation Count

90

Scopus Citation Count

96

WoS h-index

5

Scopus h-index

5

Patents

0

Projects

0

WoS Citations per Publication

8.18

Scopus Citations per Publication

8.73

Open Access Source

4

Supervised Theses

0

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JournalCount
Stem Cell Research & Therapy2
American Journal of Rhinology & Allergy1
Journal of Assisted Reproduction and Genetics1
Journal of Hazardous Materials1
Progress In Electromagnetics Research Symposium (PIERS) -- AUG 19-23, 2012 -- Moscow, RUSSIA1
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Scholarly Output Search Results

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    Article
    Citation - WoS: 1
    Citation - Scopus: 1
    Topical Intranasal Insulin Enhances Healing of Nasal Mucosa: an Experimental Animal Study
    (Sage Publications inc, 2023) Kulekci, Cagri; Ozer, Serdar; Onen, Selin; Korkusuz, Petek; Yilmaz, Taner
    Objective Aim of this study was to evaluate the effect of topical intranasal insulin on healing of nasal mucosa in a rat model. Methods Forty-eight Wistar rats, weighing between 250 and 300 g and aged 10-12 weeks were used and randomized into two equal groups. 1.9 mm curette was introduced through the left nostril and 1.9 mm mucosa from the left nasal septum was curetted. Postoperatively, animals in the control group received 1 mL of physiologic saline, 3 times a day in a nasal irrigation fashion. Animals in the experimental group received 1 mL of 5 IU/mL regular insulin in saline solution. Subjects were sacrificed after 5, 10, and 15 days and macroscopic and histomorphometric evaluations were performed. Results There were no mucosal synechiae and septal perforation macroscopically. Histological examination revealed that the defect size reduction was 21% in the saline group versus 56% in the insulin group on the fifth day (p = 0.006). There was 62% defect reduction in the saline group versus 79% in the insulin group on the 10th day (p = 0.034). On the 15th day, only 67% of saline group animals had complete defect closure, whereas 100% of animals treated with insulin had complete closure (92% vs 100% mucosal defect reduction, p = 0.036). Both edema and inflammation were less in the insulin group on 15th day (p = 0.006; p = 0.023, respectively). Conclusion The results from this study support the safety and efficacy of topical insulin on wound healing in the literature. This study could guide further experimental studies that examine human sinonasal wound healing.