Önen, Selin

Profile Picture
Profile URL
https://hdl.handle.net/20.500.14411/8366
Name Variants
Selin, Önen
Önen,S.
Önen, Selin
O., Selin
Selin, Onen
S.,Önen
O.,Selin
S.,Onen
Onen,S.
Ö.,Selin
Onen, Selin
S., Onen
Job Title
Araştırma Görevlisi
Email Address
selin.onen@atilim.edu.tr
Main Affiliation
Basic Sciences
Status
Former Staff
Website
ORCID ID
Scopus Author ID
Turkish CoHE Profile ID
Google Scholar ID
WoS Researcher ID

Sustainable Development Goals

2

ZERO HUNGER
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0

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14

LIFE BELOW WATER
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0

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17

PARTNERSHIPS FOR THE GOALS
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0

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5

GENDER EQUALITY
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16

PEACE, JUSTICE AND STRONG INSTITUTIONS
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0

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8

DECENT WORK AND ECONOMIC GROWTH
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0

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4

QUALITY EDUCATION
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0

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6

CLEAN WATER AND SANITATION
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1

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7

AFFORDABLE AND CLEAN ENERGY
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0

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10

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0

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11

SUSTAINABLE CITIES AND COMMUNITIES
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1

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9

INDUSTRY, INNOVATION AND INFRASTRUCTURE
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1

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3

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4

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12

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13

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15

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Scholarly Output

11

Articles

7

Views / Downloads

1/0

Supervised MSc Theses

0

Supervised PhD Theses

0

WoS Citation Count

90

Scopus Citation Count

96

WoS h-index

5

Scopus h-index

5

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0

Projects

0

WoS Citations per Publication

8.18

Scopus Citations per Publication

8.73

Open Access Source

4

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0

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JournalCount
Stem Cell Research & Therapy2
American Journal of Rhinology & Allergy1
Journal of Assisted Reproduction and Genetics1
Journal of Hazardous Materials1
Progress In Electromagnetics Research Symposium (PIERS) -- AUG 19-23, 2012 -- Moscow, RUSSIA1
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    Article
    Citation - WoS: 16
    Citation - Scopus: 16
    Targeted mesoporous silica nanoparticles for improved inhibition of disinfectant resistant Listeria monocytogenes and lower environmental pollution
    (Elsevier, 2021) Sudagidan, Mert; Yildiz, Gulsah; Onen, Selin; Al, Rabia; Temiz, S. Sevval Nur; Yurt, Mediha Nur Zafer; Ozalp, Veli C.
    Benzalkonium chloride (BAC) is a common ingredient of disinfectants used for industrial, medical, food safety and domestic applications. It is a common pollutant detected in surface and wastewaters to induce adverse effects on Human health as well as aquatic and terrestrial life forms. Since disinfectant use is essential in combatting against microorganisms, the best approach to reduce ecotoxicity level is to restrict BAC use. We report here that encapsulation of BAC in mesoporous silica nanoparticles can provide an efficient strategy for inhibition of mi-crobial activity with lower than usual concentrations of disinfectants. As a proof-of-concept, Listeria mono-cytogenes was evaluated for minimum inhibitory concentration (MIC) of nanomaterial encapsulated BAC. Aptamer molecular gate structures provided a specific targeting of the disinfectant to Listeria cells, leading to high BAC concentrations around bacterial cells, but significantly reduced amounts in total. This strategy allowed to inhibition of BAC resistant Listeria strains with 8 times less the usual disinfectant dose. BAC encapsulated and aptamer functionalized silica nanoparticles (AptBACNP) effectively killed only target bacteria L. monocytogenes, but not the non-target cells, Staphylococcus aureus or Escherichia coli. AptBACNP was not cytotoxic to Human cells as determined by in vitro viability assays.