Sarıçam, Ersin
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Ersin, Saricam
Saricam E.
S.,Ersin
Saricam, Ersin
Sariçam E.
E.,Sarıçam
Ersin, Sariçam
S., Ersin
E., Saricam
Sarıçam, Ersin
Ersin, Sarıçam
E.,Saricam
E., Sarıçam
Sarıçam,E.
E.,Sariçam
E., Sariçam
Sariçam, Ersin
Saricam,E.
Saricam E.
S.,Ersin
Saricam, Ersin
Sariçam E.
E.,Sarıçam
Ersin, Sariçam
S., Ersin
E., Saricam
Sarıçam, Ersin
Ersin, Sarıçam
E.,Saricam
E., Sarıçam
Sarıçam,E.
E.,Sariçam
E., Sariçam
Sariçam, Ersin
Saricam,E.
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Doçent Doktor
Email Address
ersin.saricam@atilim.edu.tr
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Internal Medical Sciences
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1NO POVERTY
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2ZERO HUNGER
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3GOOD HEALTH AND WELL-BEING
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4QUALITY EDUCATION
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5GENDER EQUALITY
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6CLEAN WATER AND SANITATION
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7AFFORDABLE AND CLEAN ENERGY
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8DECENT WORK AND ECONOMIC GROWTH
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9INDUSTRY, INNOVATION AND INFRASTRUCTURE
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10REDUCED INEQUALITIES
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11SUSTAINABLE CITIES AND COMMUNITIES
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12RESPONSIBLE CONSUMPTION AND PRODUCTION
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13CLIMATE ACTION
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14LIFE BELOW WATER
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15LIFE ON LAND
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16PEACE, JUSTICE AND STRONG INSTITUTIONS
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17PARTNERSHIPS FOR THE GOALS
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27
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216
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7
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Scholarly Output
11
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11
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46/0
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WoS Citation Count
35
Scopus Citation Count
38
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WoS Citations per Publication
3.18
Scopus Citations per Publication
3.45
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7
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0
| Journal | Count |
|---|---|
| International Journal of General Medicine | 4 |
| Current vascular pharmacology | 1 |
| Current Vascular Pharmacology | 1 |
| Frontiers in Cardiovascular Medicine | 1 |
| Journal of health sciences and medicine (Online) | 1 |
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Article Citation - WoS: 1Citation - Scopus: 2The Detailed Transseptal Puncture Technique for Optimal Closure in Patients With a Patent Foramen Ovale(Frontiers Media Sa, 2024) Ilkay, Erdogan; Saricam, Ersin; Kacmaz, Fehmi; Yakici, Aysel; Koca, Cigdem; Ozeke, Ozcan; Onal, Mehmet ZulkufBackground The closure of a patent foramen ovale (PFO) using transseptal puncture has particular advantages and disadvantages. Thus, transseptal puncture should be re-evaluated in detail. Aims We aimed to assess the effectiveness of the detailed transseptal puncture technique in patients who underwent PFO closure due to cryptogenic stroke or transient ischemic attack in terms of residual shunts and atrial fibrillation. Methods We prospectively analyzed 144 consecutive patients who underwent PFO closure by the detailed transseptal puncture technique between February 2013 and April 2023 in two centers. All of the patients had a >10 mm long-tunnel PFO. Results The procedural success rate was 100%. However, after the procedure, moderate pericardial effusion developed in one patient (0.7%) and an acute pulmonary embolism related to femoral vein thrombosis was observed in one patient (0.7%) during the first month. Complications related to the procedure were noted in two patients (1.4%) during the first month of follow-up. Residual shunts were observed in 1.4% of cases after PFO closure. Conclusion We demonstrated that the detailed transseptal technique is safe and effective for PFO closure. The detailed transseptal PFO closure technique significantly reduced the risk of atrial fibrillation, and the occurrence of residual shunts was significantly low following the closure.Article Citation - WoS: 9Citation - Scopus: 13The Evaluation of Oxidative Stress in the Young Adults With Covid-19 Mrna Vaccines Induced Acute Pericarditis- Myopericarditis(Dove Medical Press Ltd, 2022) Dursun, Ali Dogan; Saricam, Ersin; Sariyildiz, Gulcin Turkmen; Iscanli, Murat Dogan; Cantekin, Omer FarukBackground: During COVID-19 pandemic, several vaccines have been developed such as mRNA vaccines. However, acute pericarditis and myocarditis/myopericarditis cases have been described after mRNA vaccination. The mechanism for the development of cardiac involvement is unknown. Potential mechanism for oxidative stress associated with vaccine-induced heart involvement is unidentified. This study aimed to examine the role of oxidative stress and the heart involvement in young adults vaccinated with COVID-19 mRNA vaccines. Methods: In this cross-sectional study, a total of 23 participants were included and 10 of these participants were asymptomatic patients (control group). Comparison of the cardiac involvement and control group was made by using troponin I, C-reactive protein (hsCRP), D-dimer levels, and oxidative stress tests including nitric oxide, and imaging techniques (ECG, echocardiography, cardiovascular magnetic resonance). Results: The median age of acute pericarditis group (10 patients) was 22 years (Q1-Q3: 18.5-31), and the mean age was 24.4 +/- 7.5 years. The median age of myopericarditis group (3 patients) was 22 years (Q1-Q3 18.0-25.0), and the mean age was 21.6 +/- 3.5 years. All the myopericarditis cases were male. The patients with myopericarditis had higher troponin I level, hsCRP, and D-dimer levels (troponin I level; 1600.00 ng/mL; D-dimer; 1.20 mu g/mL, hsCRP; 3.0 mg/L, respectively; p < 0.05). Serum nitric oxide levels and OSI (total oxidant status, H2O2/total antioxidant status) were lower in myopericarditis group than the control and acute pericarditis group (p < 0.05). This shows inflammatory and procoagulant state. Conclusion: Vaccine-induced myopericarditis cases are associated with oxidative stress test abnormality (abnormal NO, OSI levels). However, there is no relationship between NO levels and other oxidative stress tests difference in vaccine-induced acute pericarditis. It is thought that vaccine-induced pericarditis and myopericarditis could have different pathogenesis. This could make it necessary to reassess the second dose of vaccination for vaccine-induced cardiac involvement cases.Article Clinical and Laboratory Evaluation of Acute Pericarditis Associated With Antinuclear Antibodies Positivity(Bentham Science Publ Ltd, 2023) Dursun, Ali Dogan; Saricam, Ersin; Erdem, Hakan; Sariyildiz, Gulcin Turkmen; Ozyer, Esref Umut; Bozkurt, Engin; Cantekin, Omer FarukBackground Up to 30% of patients with acute pericarditis develop recurrent pericarditis. Acute pericarditis may be a manifestation of an underlying systemic autoimmune disease. Therefore, we evaluated the characteristics of patients with acute pericarditis according to antinuclear antibodies (ANA) positivity/negativity. Methods Participants with acute pericarditis and negative ANA (n=29), recurrent pericarditis with positive ANA (n=30) and healthy controls (n=11) were examined. The groups were compared using serum parameters (ANA, C-reactive protein, leucocyte count, erythrocyte sedimentation rate, total antioxidant status, nitric oxide (NO), and oxidative stress index (OSI)) and imaging techniques (electrocardiogram, echocardiography, cardiovascular magnetic resonance, and venous Doppler ultrasound). Results In females, acute pericarditis associated with ANA occurred more frequently (p<0.001). ANA-positive acute pericarditis had significantly lower NO and OSI (p<0.05 and p<0.001, respectively) and pericardial inflammation on magnetic resonance. We found a pulmonary embolism in one patient with positive ANA. Slow venous flow (SVF) occurred more often in acute pericarditis associated with ANA than in the ANA-negative group on venous ultrasound (p<0.05). The prevalence of positive ANAs was 1.6 times higher among SVF patients than in controls. Conclusion This study suggests that acute pericarditis associated with ANA is more common in middle-aged females. SVF and lower oxidative stress tests were more common in patients with ANA-associated acute pericarditis. Acute pericarditis associated with ANA could be considered as a hypercoagulable state. Therefore, all newly diagnosed pericarditis patients (especially females) should be checked for ANA positivity. Awareness of this coexistence should be promptly addressed to establish management strategies.Article Citation - WoS: 3Citation - Scopus: 1Caval Valve Implantation Procedure in 7 Cases of Torrential Tricuspid Regurgitation and Step-By Description of the Procedure(Kare Publ, 2025) Sarıçam, Ersin; Barcin, Cem; Çelebi, Aksüyek Savaş; Asfour, Mohamed; Bozbas, Huseyin; İlkay, Erdoğan; Cam, Ersin; Celebi, Savas A.Tricuspid regurgitation (TR) is an increasingly prevalent and clinically significant health problem.1 Due to the growing understanding of the importance of TR, the tricuspid valve has transitioned from being a forgotten valve to one of significant concern. Tricuspid regurgitation is often functional, and as it progresses to moderate or severe stages, hospital admissions increase and prognosis worsens.1,2 There are no effective pharmacological treatments for TR, and the 5-year survival rate with medical management is reported to be less than 50%.3 Therefore, early diagnosis and timely intervention for TR is crucial. Both surgical and percutaneous treatment options are available for severe TR. The mortality rate for isolated TR surgery is generally high.4 In recent years, transcatheter treatments have become feasible for this patient group, and accumulating evidence shows that transcatheter treatment is superior to medical management.5,6 Transcatheter interventions for TR can be performed in 4 ways, 2 involving repair and 2 involving valve We aimed to present our experience with transcatheter caval valve implantation (CAVI) in 7 patients with torrential TR who were not suitable for surgical intervention or transcatheter edge-to-edge repair (T-TEER) due to severe coaptation defects, review the current literature, and provide a step-by-step description of the procedure.Article Akut Kalp Yetmezlikli Hastalarda Kılavuz Tedavi: Sol Ventrikül Doluş Bulguları ve Nt-probnp(2020) Sarıçam, Ersin; Öcal, ArslanAmaç: N-terminal pro B tip natriüretik peptid akut kalp yetmezliğinde sıklıkla kullanılır. Bu çalışmada, akut kalp yetmezlikli hastaların Doppler transmitral akım parametrelerinin hastaneye kabul ve taburculukta N-terminal pro B tip natriüretik peptid gibi faydalı bir yaklaşım olup olamayacağını araştırdık. Gereç ve Yöntem: Prospective randomize tasarlanan bu çalışma Ekim 2019-Mart 2020 arası acil bölümüne kabul edilen 57 hastaya kapsamaktadır. Tüm hastalar New York Heart Association sınıf IV olup sinüs ritminde ve önceden dilate kardiyomiyopati tanısı almışlardı. Hastalara giriş ve taburculukta transtorasik ekokardiyografi ile sol ventrikül diyastolik doluş paternleri değerlendirildi. Giriş ve çıkış N-terminal pro B tip natriüretik peptid seviyeleri sol venrtrikül doluş bulguları ile karşılaştırıldı. Bulgular: Ortalama yaş 64,94±5,56 idi. Girişte tüm hastaların sol ventrikül doluş paternleri restriktif tip doluş bozukluğu idi. Taburculukta 46 hasta anormal relaksasyon bozukluğu (Tip I), 11 hasta pseudonormal doluş bozukluğu (Tip II) vardı. N-terminal pro B tip natriüretik peptid seviyeleri girişte 8004,75±743 pg/mL, taburculukta 1645,17±104,58 pg/mL idi. Ortalama e/e’ oranı girişte 14,83±0,25 taburculukta 7,70±0,14 idi. Ortalama E/A oranı girişte 2,51±0,35 taburculukta 1,42±0,33 idi. Anormal relaksasyon tipte N-terminal pro B tip natriüretikpeptidseviyeleri 1440,43±144,75 pg/mL, oysa pseudonormal pattern de N-terminal pro B tip natriüretik peptid seviyeleri 1957,60±64,00 pg/mL (p=0,003). Sonuç: Akut kalp yetmezlikli hastalarda sol ventrikül doluş paternleri N-terminal pro B tip natriüretik peptid rehberliği gibi başarılı bir şekilde kullanılabileceğini göstermiştir.Article Comparison of Amiodarone Loading Dosage in the Treatment of Postoperative Atrial Fibrillation: High Versus Standard Dose Treatment(Bentham Science Publ Ltd, 2024) Sarıçam, E.; Öcal, A.; Iscanlı, M.D.; Bozkurt, E.; Ilkay, E.; Cantekin, ÖF.BACKGROUND: Postoperative atrial fibrillation (POAF) is associated with poor outcomes, including hemodynamic instability, stroke, myocardial infarction, and death. In hemodynamic stable patients, the rhythm-control strategy is more advantageous than rate control. Current standard intravenous amiodarone administration has limited success and a delayed effect; the acute success rate is 44% (8-12 h to several days). PURPOSE: The aim of this study was to evaluate the effectiveness of higher amiodarone loading dosage to restore sinus rhythm in patients with POAF after noncardiac surgery. METHODS: This is a prospective, randomized, controlled single-center study. The study included 39 patients with POAF, divided into group I (n=27) (intravenous 600 mg amiodarone loading dosage over 2 h and infusion of 50 mg/h over a 24-h period) and group II (n=12) (standard protocol; 300 mg of bolus intravenously in 30 min and infusion of 50 mg/h over a 24-h period). The primary endpoint of the study was a restoration of sinus rhythm at the 24th hour. RESULTS: Baseline clinical, laboratory and echocardiographic characteristics of both groups were similar. The patients with higher loading amiodarone dosage had earlier restoration of sinus rhythm (2.38 ± 1.41 vs 8.66 ± 2.87 h, respectively; p=0.015). There was no significant difference in achieving sinus rhythm at the 24th hour between both groups. CONCLUSION: Higher loading amiodarone dosage increased early conversions to sinus rhythm compared with standard amiodarone protocol in patients with POAF. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.Article Citation - WoS: 20Laboratory and Imaging Evaluation of Cardiac Involvement in Patients With Post-Acute Covid-19(Dove Medical Press Ltd, 2021) Saricam, Ersin; Dursun, Ali Dogan; Sariyildiz, Gulcin Turkmen; Can, Nalan; Bozkurt, Engin; Gonullu, Ugur; Unlu, MustafaBackground: In the post-acute COVID-19 syndrome, many patients suffer from palpitations, effort-associated fatigue, and even sudden death. The mechanism of heart involvement in this syndrome is uncertain. The main purpose of the study was to identify possible cardiac involvement causes in patients with post-acute COVID-19 by using biomarkers such as NT-proBNP and nitric oxide (NO) and cardiac imaging modalities. Methods: In this cross-sectional study, a total of 105 participants were included according to the existence of symptoms, and 40 of these participants were asymptomatic patients. The ages of the participants ranged from 20 to 50 years. All patients were healthy before COVID-19. The symptoms were defined as palpitations and/or fatigue association with exercise in post-acute COVID-19 term. The comparison of the two groups was made by using biochemical parameters (NT-proBNP, Troponin I, NO) and imaging techniques (echocardiography, cardiovascular magnetic resonance (CMR) and cardiac positron emission tomography (PET)). Results: The symptomatic patients had higher NT-proBNP levels compared with asymptomatic patients (132.30 +/- 35.15; 76.86 +/- 16.79, respectively; p < 0.001). Interestingly, the symptomatic patients had lower NO levels than asymptomatic patients (9.20 +/- 3.08; 16.15 +/- 6.02, respectively; p < 0.001). Echocardiography and CMR were normal. However, we found regional increased 18F-FDG uptake on cardiac PET to be compatible with myocardial fatigue. Conclusion: We found elevated NT-proNBP levels, low serum NO levels, and increased 18F-FDG uptake on cardiac PET in post-acute COVID syndrome. Cardiac PET could replace or be added to CMR for detecting subtle subacute/chronic myocarditis. The follow-up of patients with post-acute COVID-19 could target the possibility of risk of heart failure.Article Citation - Scopus: 20Laboratory and Imaging Evaluation of Cardiac Involvement in Patients With Post-Acute Covid-19(Dove Medical Press Ltd, 2021) Sarıçam,E.; Dursun,A.D.; Sarıyıldız,G.T.; Can,N.; Bozkurt,E.; Gönüllü,U.; Ünlü,M.Background: In the post-acute COVID-19 syndrome, many patients suffer from palpitations, effort-associated fatigue, and even sudden death. The mechanism of heart involvement in this syndrome is uncertain. The main purpose of the study was to identify possible cardiac involvement causes in patients with post-acute COVID-19 by using biomarkers such as NT-proBNP and nitric oxide (NO) and cardiac imaging modalities. Methods: In this cross-sectional study, a total of 105 participants were included according to the existence of symptoms, and 40 of these participants were asymptomatic patients. The ages of the participants ranged from 20 to 50 years. All patients were healthy before COVID-19. The symptoms were defined as palpitations and/or fatigue association with exercise in post-acute COVID-19 term. The comparison of the two groups was made by using biochemical parameters (NT-proBNP, Troponin I, NO) and imaging techniques (echocardiography, cardiovascular magnetic resonance (CMR) and cardiac positron emission tomography (PET)). Results: The symptomatic patients had higher NT-proBNP levels compared with asymptomatic patients (132.30±35.15; 76.86±16.79, respectively; p < 0.001). Interestingly, the symptomatic patients had lower NO levels than asymptomatic patients (9.20±3.08; 16.15 ±6.02, respectively; p < 0.001). Echocardiography and CMR were normal. However, we found regional increased 18F-FDG uptake on cardiac PET to be compatible with myocardial fatigue. Conclusion: We found elevated NT-proNBP levels, low serum NO levels, and increased 18F-FDG uptake on cardiac PET in post-acute COVID syndrome. Cardiac PET could replace or be added to CMR for detecting subtle subacute/chronic myocarditis. The follow-up of patients with post-acute COVID-19 could target the possibility of risk of heart failure. © 2021 Sarıçam et al. This work is published and licensed by Dove Medical Press Limited.Article Citation - WoS: 2Citation - Scopus: 2Association Between the Degree of Nonalcoholic Fatty Liver Disease and Nocturnal Hypertension(Lippincott Williams & Wilkins, 2025) Astan, Ramazan; Kacmaz, Fehmi; Saricam, Ersin; Ozyer, Esref Umut; Ilkay, ErdoganNighttime blood pressure (BP) decreases have prognostic significance owing to circadian patterns. The prevalence of nonalcoholic fatty liver disease (NAFLD) has rapidly increased in recent years. We aimed to investigate circadian blood pressure changes in patients with NAFLD. The present study included 114 patients diagnosed with nonalcoholic fatty liver disease and no previous hypertension diagnosis. Thirty patients comprised the control group (no hepatosteatosis and no hypertension). The patients were divided into 3 groups based on nocturnal BP dipping. Blood pressure patterns using night-day ratios were classified as dipper (ratio <= 0, 9), nondipper (0, 9 < ratio <= 1, 0), or nocturnal hypertension (ratio > 1, 0). There were no significant differences in sex, age, presence of diabetes, or biochemical test results between the groups. According to the blood pressure pattern, the nondipper rate in the hepatosteatosis group was significantly higher than that in the control group. Patients were compared in terms of the presence and severity of hepatosteatosis according to night blood pressure patterns. A significant difference was observed between the groups (P < .001 and P = .001, respectively). We found an association between hepatosteatosis severity and night blood pressure patterns. Patients with nonalcoholic fatty liver disease have a higher incidence of nocturnal hypertension. We observed impaired circadian blood pressure changes in patients with nonalcoholic fatty liver disease.Article The Evaluation of P-Wave Parameters in Patients With Percutaneous Closure of Atrial Septal Defect(Wiley, 2025) Astan, Ramazan; Kacmaz, Fehmi; Saricam, Ersin; Ilkay, ErdoganBackground: Atrial septal defect (ASD) can lead to volume overload and related changes in P-wave parameters in surface electrocardiograms of these patients. In this study, we aimed to evaluate the effect of volume overload on P-wave parameters in patients with ASD. Materials and methods: This study is a retrospective cohort analysis. A total of 142 patients with secundum ASD who underwent percutaneous closure were evaluated. P-wave duration (Pmax) and P-wave dispersion (PWD) were measured on the surface ECG before and 1 h after the closure procedure. We evaluated P-wave parameters in terms of defect size, duration of the volume overload, and closure device sizes. Results: Pmax and PWD were significantly decreased after the procedure compared with the values before the procedure (p < 0.001). Pmax values had a statistically significant correlation with ASD size (< 20 mm or >= 20 mm) both before and after the procedure. Pmax values were significantly higher in patients older than 30 years of age (119.6 +/- 19.5 vs. 102.7 +/- 17.1 ms, respectively; p = 0.039). A significantly positive correlation was found between pre- and post-procedural Pmax and defect sizes (r = 0.474, p = 0.019 and r = 0.4233, p = 0.04, respectively). However, no positive correlation between PWD and defect age and size was present. Conclusion: Percutaneous closure of ASD is associated with an immediate decrease in both Pd and Pmax that seems to be related to the acute volume overload cessation in cardiac chambers.
