Korkmaz Özkan, Filiz

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https://hdl.handle.net/20.500.14411/6821
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Korkmaz Ozkan,Filiz
K.,Filiz
F.,Korkmaz Ozkan
Filiz, Korkmaz Özkan
Korkmaz Ozkan,F.
K.Ö.Filiz
Korkmaz Özkan,F.
K. O. Filiz
Korkmaz F.
F.,Korkmaz Özkan
F., Korkmaz Ozkan
Filiz, Korkmaz Ozkan
Filiz Korkmaz Özkan
F., Korkmaz Özkan
Korkmaz Ozkan, Filiz
Korkmaz Özkan, Filiz
K. Ö. Filiz
K., Filiz
Özkan, Filiz Korkmaz
Korkmaz, Filiz
Job Title
Profesör Doktor
Email Address
filiz.korkmaz@atilim.edu.tr
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Physics Group
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https
ORCID ID
0000-0003-3512-3521
Scopus Author ID
8664101000
Turkish CoHE Profile ID
Google Scholar ID
4NU4lXwAAAAJ
WoS Researcher ID
2752134

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Author: Bozatli, LeylaStart date: 2020

Scholarly Output Search Results

Now showing 1 - 2 of 2
  • Thumbnail Image
    Article
    Author Correction: Using Urine Ftir Spectra To Screen Autism Spectrum Disorder
    (Nature Portfolio, 2024) Sarigul, Neslihan; Bozatli, Leyla; Kurultak, Ilhan; Korkmaz, Filiz
    [No Abstract Available]
  • Thumbnail Image
    Article
    Citation - WoS: 7
    Citation - Scopus: 6
    Using urine FTIR spectra to screen autism spectrum disorder
    (Nature Portfolio, 2023) Sarigul, Neslihan; Bozatli, Leyla; Kurultak, Ilhan; Korkmaz, Filiz
    Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder caused by multiple factors, lacking clear biomarkers. Diagnosing ASD still relies on behavioural and developmental signs and usually requires lengthy observation periods, all of which are demanding for both clinicians and parents. Although many studies have revealed valuable knowledge in this field, no clearly defined, practical, and widely acceptable diagnostic tool exists. In this study, 26 children with ASD (ASD+), aged 3-5 years, and 26 sex and age-matched controls are studied to investigate the diagnostic potential of the Attenuated Total Reflectance-Fourier Transform Infrared (ATR-FTIR) spectroscopy. The urine FTIR spectrum results show a downward trend in the 3000-2600/cm region for ASD+ children when compared to the typically developing (TD) children of the same age. The average area of this region is 25% less in ASD+ level 3 children, 29% less in ASD+ level 2 children, and 16% less in ASD+ level 1 children compared to that of the TD children. Principal component analysis was applied to the two groups using the entire spectrum window and five peaks were identified for further analysis. The correlation between the peaks and natural urine components is validated by artificial urine solutions. Less-than-normal levels of uric acid, phosphate groups, and ammonium (NH4+) can be listed as probable causes. This study shows that ATR-FTIR can serve as a practical and non-invasive method to screen ASD using the high-frequency region of the urine spectrum.