Demir, Canan

Now showing 1 - 2 of 2

Citation - WoS: 7
Citation - Scopus: 8
Laparoscopic Sleeve Gastrectomy With Transit Loop Bipartition and Transit Bipartition in Type 2 Diabetic Patients With Obesity: a Retrospective Analysis
(Lippincott Williams & Wilkins, 2023) Demir, Canan; Arslan, Ergin; Sariyildiz, Guelcin; Anil, Cueneyd; Banli, Oktay
Aim:We aimed to compare 1-year postoperative results of patients with obesity and type 2 diabetes mellitus (T2DM) who underwent laparoscopic sleeve gastrectomy with transit bipartition (LSG-TB) and transit loop bipartition (LSG-TLB) and mini gastric bypass (MGB). Patients and Methods:This is a retrospective comparison of 2 novel bariatric surgery techniques with MGB. Primary outcome measure of the study was a rate of T2DM remission. Secondary outcomes included excess body mass index (BMI) loss, improvement in hepatosteatosis, and duration of operation. Revision surgery needs were also assessed. Results:Overall, 32 patients underwent the LSG-TLB, 15 underwent LSG-TB, and 50 underwent MGB. Mean age and sex distribution were comparable for all groups. Presurgical BMI was similar in MGB and LSG + TB groups, whereas LSG + TLB group had significantly lower BMI values compared with the MGB group. In both groups, BMI values reduced significantly compared with respective baseline values. Excess BMI loss was significantly higher in patients who underwent LSG-TLB compared with patients treated with LSG-TB and MGB. Bariatric surgery procedures lasted shorter in LSG-TLB than in LSG-TB. However, the shortest of all was MGB. The remission of T2DM rates were 71% and 73.3% in LSG-TLB and LSG-TB groups, respectively (P > 9.999). The rate of revision surgeries was comparable in both groups. Conclusion:In conclusion, LSG-TLB took less time and provided significantly higher excess BMI loss compared with LSG-TB. T2DM remission and improvement rates were similar in both groups. LSG-TLB seemed like a promising bariatric surgery technique in patients with obesity and T2DM.
Citation - WoS: 5
The Evaluation of Serum Endocan, Interleukin-6, and Crp Levels Following Sleeve Gastrectomy
(Dove Medical Press Ltd, 2023) Sariyildiz, Gulcin Turkmen; Demir, Canan Cicek; Demir, Mehmet Emin; Arslan, Aykut Ilker; Banli, Oktay; Dursun, Ali Dogan
Background: The excessive accumulation of fat tissue in obesity is the source of chronic low-level inflammation and causes future dysmetabolic and cardiovascular disorders. Removal of this excessive fat tissue with the aid of bariatric surgery (BS) techniques, such as sleeve gastrectomy, may reverse adverse inflammatory outcomes. The aim of this study is to investigate the impact of sleeve gastrectomy on inflammatory markers, specifically endocan, IL-6, and CRP, in individuals with obesity.Methods: Thirty-two patients with class 3 obesity and class 2 obesity + comorbidities were enrolled in the study. Clinical characteristics including age, comorbidity, body mass index (BMI), waist, and hip circumferences of the participants were noted before and 3 months after sleeve gastrectomy. Blood samples were collected during those periods to assess biochemical features such as serum endocan, interleukin-6 (IL-6), C-reactive peptide, fasting insulin, glycosylated hemoglobin A1c levels, and lipid panel. A statistical package program was used for the analysis of those parameters, and p<0.05 was accepted as significant at a 95.0% confidence interval.Results: BMI reduced from 43.55 +/- 6.78 to 36.16 +/- 6.14 kg/m(2) within 3 months following BS (p<0.001). Preoperative serum endocan, IL-6, and CRP levels were correlated with BMI, and in line with BMI reduction, their serum levels decreased after BS (p<0.05). HOMA-IR also reduced after BS, and both in the pre and post-BS periods correlated with BMI, IL-6, endocan, and CRP levels (p<0.05). The mean total body weight loss was 20.4% within 3 months post-BS.Conclusion: BS techniques are effective in weight loss and reversing the inflammatory processes caused by obesity. Serum endocan, IL-6, and CRP levels are promising markers for describing obesity-related inflammation and objectively checking the alleviation of inflammation following BS.

Journal	Count
Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi	1
Gülhane Tıp Dergisi	1
International Journal of General Medicine	1
International Urology and Nephrology	1
Medicine Science	1

Demir, Canan

Profile URL

Name Variants

Job Title

Email Address

Main Affiliation

Status

Website

ORCID ID

Scopus Author ID

Turkish CoHE Profile ID

Google Scholar ID

WoS Researcher ID

Sustainable Development Goals

2

ZERO HUNGER

0

Research Products

11

SUSTAINABLE CITIES AND COMMUNITIES

0

Research Products

14

LIFE BELOW WATER

0

Research Products

6

CLEAN WATER AND SANITATION

0

Research Products

1

NO POVERTY

0

Research Products

5

GENDER EQUALITY

0

Research Products

9

INDUSTRY, INNOVATION AND INFRASTRUCTURE

0

Research Products

16

PEACE, JUSTICE AND STRONG INSTITUTIONS

0

Research Products

17

PARTNERSHIPS FOR THE GOALS

0

Research Products

15

LIFE ON LAND

0

Research Products

10

REDUCED INEQUALITIES

0

Research Products

7

AFFORDABLE AND CLEAN ENERGY

0

Research Products

8

DECENT WORK AND ECONOMIC GROWTH

0

Research Products

4

QUALITY EDUCATION

0

Research Products

12

RESPONSIBLE CONSUMPTION AND PRODUCTION

0

Research Products

3

GOOD HEALTH AND WELL-BEING

4

Research Products

13

CLIMATE ACTION