WoS
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Article Citation - WoS: 14Citation - Scopus: 15An Accurate Optical Gain Model Using Adaptive Neuro-Fuzzy Inference System(Natl inst Optoelectronics, 2009) Celebi, F. V.; Altindag, T.; Computer EngineeringThis paper presents a single, simple, new and an accurate optical gain model based on adaptive neuro-fuzzy inference system (ANFIS) which combines the benefits of Artificial Neural Networks (ANNs) and Fuzzy Inference Systems (FISs). The dynamic optical gain model results are in very good agreement with the previously published experimental findings.Conference Object Citation - WoS: 1Citation - Scopus: 1Alternative Solutions for Urban Housing: the Case of Batikent Settlement, Ankara, Turkey(Wit Press, 2017) Atici, MelikeThe present study is an effort to remember and reveal the potentials of Batikent settlement which was realized in the west part of the capital city of Turkey, Ankara in 1980s. In the period after 2nd World War, big cities in Turkey, like many other countries, entered in the process of rapid urbanization under the influence of mechanization in agriculture and migration from rural to urban areas. Increase in the population of cities and scarcity of shelter brought with the emergence of squatter areas. Batikent settlement was developed as a flagship solution to this housing problem and established a precedent with its model of implementation for future urban cohabitations. Batikent, as a new settlement area, was initiated by Municipality of Ankara and developed a never-before-seen operational model with three main collaborators: central government, municipality and association of housing cooperatives (Kent-Koop). Separation of roles - such as passing fiscal and housing laws, providing financial support, expropriation of land, constructing technical infrastructure, establishing municipal and commercial services, preparing master plan and designing site and house plans - through these collaborators provided this new mass development project with effective, practical and economical solutions. This study will focus on how Batikent was developed as a platform for innovation with the operational model based on dialogue between different parties. Collection of plans from master plans to layouts of apartments, meeting notes and feasibility studies documented and published by Kent-Koop will be used in this study to achieve a better understanding of the planning process of this exemplary quarter.Article Applications of Non-Unique Fixed Point Theorem of Ciric To Nonlinear Integral Equations(int Center Scientific Research & Studies, 2019) Sevinik-Adiguzel, Rezan; Karapinar, Erdal; Erhan, Inci M.In this paper we discuss the application of the non-unique fixed point theorem of Ciric to nonlinear Fredholm integral equations. We establish an existence theorem for the solutions of such integral equations and apply the theorem to particular examples.Article Citation - WoS: 9Citation - Scopus: 17An Assessment of the Software Engineering Curriculum in Turkish Universities: Ieee/Acm Guidelines Perspective(Fac Teacher Education, 2011) Mishra, Alok; Yazici, Ali; Software EngineeringSoftware engineering (SE) education has been emerging as an independent and mature discipline. Accordingly, various studies are being done to provide guidelines for SE education curriculum design. This paper presents software engineering education evolvement in Turkey, present SE education scenario in different universities along with the significance of software technology parks in relevance to software engineering education. The objective of this paper is to provide an assessment of SE curriculum in Turkish Universities with respect to IEEE/ACM guidelines given in SEEK (2004). This study will provide a guideline to universities conducting an SE programme at undergraduate level to align their course curriculum with IEEE/ACM guidelines (SEEK, 2004).Conference Object ATA50 TELESCOPE: HARDWARE(Universidad Nacional Autonoma Mexico instituto Astronomia, 2014) Yesilyaprak, C.; Yerli, S. K.; Aksaker, N.; Yildiran, Y.; Guney, Y.; Gucsav, B. B.; Yasar, E.ATA50 Telescope is a new telescope with RC optics and 50 cm diameter. It was supported by Atatiirk University Scientific Research Project (2010) and established at about 2000 meters altitude in city of Erzurum in Turkey last year. The observations were started a few months ago under the direction and control of Atatiirk University Astrophysics Research and Application Center (ATASAM). The technical properties and infrastructures of ATA50 Telescope are presented and we have been working on the robotic automation of the telescope as hardware and software in order to be a ready-on-demand candidate for both national and international telescope networks.Article Citation - WoS: 5Citation - Scopus: 5Automorphisms of the mapping class group of a nonorientable surface(Springer, 2017) Atalan, Ferihe; Szepietowski, BlazejLet S be a nonorientable surface of genus g >= 5 with n >= 0 punctures, and Mod(S) its mapping class group. We define the complexity of S to be the maximum rank of a free abelian subgroup of Mod(S). Suppose that S-1 and S-2 are two such surfaces of the same complexity. We prove that every isomorphism Mod(S-1) -> Mod(S-2) is induced by a diffeomorphism S-1 -> S-2. This is an analogue of Ivanov's theorem on automorphisms of the mapping class groups of an orientable surface, and also an extension and improvement of the first author's previous result.Article Citation - WoS: 3Citation - Scopus: 2Bacterial Microbiota and Chemical Properties of Turkish Tarhana(Slovak Univ Agriculture Nitra, 2022) Omeroglu, Esra Ersoy; Can, Oezge; Temiz, Sevval Nur; Al, Rabia; Altunbas, Osman; Soyucok, Ali; Sudagidan, MertTarhana is one of the traditional Turkish fermented food and it is served as a soup. In this study, bacterial microbiota and chemical properties (acidity, salt, and moisture content) of tarhana samples (n=96) were examined. The metagenomic analysis revealed that Firmicutes were the dominant phylum and Bacillaceae, Enterococcaceae, Paenibacillaceae, Enterobacteriaceae, and Clostridiaceae were the dominant bacterial families. In the samples, Bacillus, Enterococcus, and Paenibacillus were mostly identified at the genus level. Alpha diversity and evenness showed that sample 30 had the highest diversity collected from Izmir. Principal Coordinate Analysis was used to identify relationships of samples at different taxonomic levels and it was found that most of the samples were closely related at the phylum level. Chemical analysis indicated that the acidity of tarhana samples varied between 5.00% and 42.5%, moisture contents were 4.39- 18.66% and salt values were from 0.32% to 6.64%. The results of this study extensively demonstrated the chemical properties and the dominant bacterial communities present in tarhana samples collected from different parts of Turkiye.Article Besir Fuad's voltaire: Liberating the Individual(Routledge Journals, Taylor & Francis Ltd, 2022) Muhurcuoglu, KorhanBesir Fuad (1852?-1887) is an obscure figure among late nineteenth century Ottoman intellectuals known for his materialistic views which were unprecedented under the Hamidian regime (1876-1909) and who shocked his contemporaries by committing suicide at an early age, leaving a note and a letter containing his last impressions and world view. Just months before his suicide, Besir Fuad published a Voltaire biography in which he commemorates him as an Enlightenment ideal to be emulated in humankind's struggle against religious intolerance. In this article, Besir Fuad's Voltaire (1886) is examined, arguing that the monograph was, though in an embryonic form, an early expression and defence of individual liberty, based on a materialistic world view that aims at demystification of the prevailing customs and morals as irrational and superstitious absurdities to pave the way for a future society in which the individual would be in liberty.Article Citation - WoS: 4Best Proximity Point for Certain Proximal Contraction Type Mappings(Univ Prishtines, 2018) Alqahtani, Badr; Hamzehnejadi, Javad; Karapinar, Erdal; Lashkaripour, RahmatollahIn this paper, we introduce the new notion of generalized proximal alpha-h-phi-contraction mappings and investigate the existence of the best proximity point for such mappings in the complete metric spaces.Article Citation - WoS: 5Citation - Scopus: 7Biological System Analysis in Bioinspired Conceptual Design (bicd) for Bioinspired Robots(Romanian Soc Control Tech informatics, 2011) Eroglu, Aylin Konez; Eroğlu, Aylin Konez; Erden, Zuhal; Erden, Zühal; Erden, Abdulkadir; Erden, Abdulkadir; Eroğlu, Aylin Konez; Erden, Zühal; Erden, Abdulkadir; Department of Mechatronics Engineering; Department of Mechatronics Engineering; Mechatronics Engineering; Mechatronics Engineering; Department of Mechatronics Engineering; Mechatronics EngineeringBioinspired design (BID) provides a systematic way for bioinspired applications. Although several BID approaches as well as some tools and databases are available in the literature, the studies on BID are still challenging for designers and/or engineers because of limitations of current BID approaches. There are mainly two directions related with these limitations. One of them is the representation of knowledge on biological systems and the second is the problem of transforming this knowledge into engineering domain. These limitations expose two questions; firstly, "What knowledge is required to describe biological systems?" and "How this knowledge is represented?" and secondly, "How this knowledge is transformed into the engineering domain?". This paper presents a study which aims to answer the first question about knowledge required to represent biological systems. This knowledge is obtained during "Analysis of Biological Systems" stage of a new suggested bioinspired conceptual design (BICD) procedure.Conference Object Citation - WoS: 1Citation - Scopus: 3Boundary Element Method for Optical Force Calibration in Microfluidic Dual-Beam Optical Trap(Spie-int Soc Optical Engineering, 2015) Solmaz, Mehmet E.; Cetin, Barbaros; Baranoglu, Besim; Serhathoglu, Murat; Biyikh, NeemiThe potential use of optical forces in microfluidic environment enables highly selective bio-particle manipulation. Manipulation could be accomplished via trapping or pushing a particle due to optical field. Empirical determination of optical force is often needed to ensure efficient operation of manipulation. The external force applied to a trapped particle in a microfluidic channel is a combination of optical and drag forces. The optical force can be found by measuring the particle velocity for a certain laser power level and a multiplicative correction factor is applied for the proximity of the particle to the channel surface. This method is not accurate especially for small microfluidic geometries where the particle size is in Mie regime and is comparable to channel cross section. In this work, we propose to use Boundary Element Method (BEM) to simulate fluid flow within the micro-channel with the presence of the particle to predict drag force. Pushing experiments were performed in a dual-beam optical trap and particle's position information was extracted. The drag force acting on the particle was then obtained using BEM and other analytical expressions, and was compared to the calculated optical force. BEM was able to predict the behavior of the optical force due to the inclusion of all the channel walls.Article Can Computers Read a Text With Stress?(Ahmet Yesevi Univ, 2013) Uslu, I. Baran; Demir, Nurettin; Ilk, H. Gokhan; Yilmaz, A. Egemen; Department of Electrical & Electronics EngineeringToday prosodic elements such as stress, intonation and melody can be examined through computer-assisted techniques. The identification and analysis of acoustic qualities provide significant clues as to the suprasegmental aspects of speech. In this study a system was designed to enable speech synthesis using a Turkish text. This synthesizer was used to analyze the melodic sructures of selected sentences. Any speech synthesized by a computer needs to be equipped with a melodic model so that it will sound natural to the ear. Within the context of this study a melodic model was also suggested, and the elements of this model were analyzed and discussed in terms of the rules of linguistics.Article Citation - WoS: 3Candu Reactors With Reactor Grade Plutonium/Thorium Carbide Fuel(Carl Hanser verlag, 2011) Sahin, S.; Khan, M. J.; Ahmed, R.Reactor grade (RG) plutonium, accumulated as nuclear waste of commercial reactors can be re-utilized in CANDU reactors. TRISO type fuel can withstand very high fuel burn ups. On the other hand, carbide fuel would have higher neutronic and thermal performance than oxide fuel. In the present work, RG-PuC/ThC TRISO fuels particles are imbedded body-centered cubic (BCC) in a graphite matrix with a volume fraction of 60%. The fuel compacts conform to the dimensions of sintered CANDU fuel compacts are inserted in 37 zircolay rods to build the fuel zone of a bundle. Investigations have been conducted on a conventional CANDU reactor based on GENTILLYII design with 380 fuel bundles in the core. Three mixed fuel composition have been selected for numerical calculation; (1) 10% RG-PuC + 90% ThC; (2) 30% RG-PuC + 70% ThC; (3) 50% RG-PuC + 50% ThC. Initial reactor criticality values for the modes (I), (2) and (3) are calculated as k(infinity,0) = 1.4848, 1.5756 and 1.627, respectively. Corresponding operation lifetimes are similar to 2.7, 8.4, and 15 years and with burn ups of similar to 72000, 222 000 and 366 000 MW.d/tonne, respectively Higher initial plutonium charge leads to higher burn ups and longer operation periods. In the course of reactor operation, most of the plutonium will be incinerated. At the end of life, remnants of plutonium isotopes would survive; and few amounts of uranium, americium and curium isotopes would be produced.Article Citation - Scopus: 1Cannabinoid Receptor Ligands Modulate Fibrosis and Inflammation in Idiopathic Pulmonary Fibrosis: a Preliminary Study(Tubitak Scientific & Technological Research Council Turkey, 2024) Kose, Sevil; Onen, Selin; Gizer, Merve; Boduroglu, Esin; Gonullu, Ugur; Korkusuz, PetekBackground/aim: No specific pharmacological treatment regimen for idiopathic pulmonary fibrosis (IPF) exists. Therefore, new antiinflammatory therapeutic strategies are needed. Cannabinoids (CBs), known for their inflammation-modulating and antifibrotic effects, may be potential medication candidates for treating IPF. We aim to evaluate the inflammation-modulating and antifibrotic effects of CB receptor (CBR) agonists and antagonists in lipopolysaccharide-stimulated normal human lung fibroblast, epithelial cells, IPF fibroblast cells, and monocytes. Materials and methods: We detected CBRs in normal human lung fibroblasts (LL24) and IPF fibroblast cells (LL29), epithelial cells (A549) and monocytes (THP-1) by flow cytometry. We determined TGF-(31, IL-8, and TNF-alpha inflammatory cytokines in the LL24, LL29, A549, and THP-1 cell culture supernatants on days 1 and 5 by ELISA. We evaluated the cell viability in LL24, LL29, and A549 cells on days 1, 3, and 5 spectrophotometrically and detected collagen Type I (ColI) production in the LL24 and LL29 cell culture supernatants on days 1, 3, and 5 by ELISA. Results: LL24, LL29, A549, and THP-1 cells exhibited CB1 (CB1R) and CB2 (CB2R) receptors. CB1R and CB2R agonists WIN55,2122 and JWH015 inhibited fibroblastic and epithelial cell proliferation on day 5. TGF-(31 and TNF-alpha release increased, while IL-8 release decreased in LL24, LL29, A549, and THP-1 cells in response to the administration of WIN55,212-2 and JWH015 at a 10-2 mM concentration. CB1R and CB2R antagonists AM251 and AM630 did not block agonistic responses, suggesting a nonclassical CBRmediated pathway. CB2R agonist JWH015 decreased ColI expression in IPF lung fibroblasts LL29 on day 3. Conclusion: These results suggest that CB signaling regulates the progression of pulmonary inflammation and fibrosis via CBR activation. This may offer a potential pharmacological tool for developing antifibrosis therapies.Article Challenges Faced by Pediatric Patients With Multiple Sclerosis During Disease Progression and Treatment: A Multicenter Cross-Sectional Study in Turkiye(Asean Neurological Assoc, 2025) Yuksel, Didem; Yardimci, FigenBackground & Objective: Multiple sclerosis is a chronic and progressive disease characterized by inflammation, demyelination and degeneration of the central nervous system. This study aimed to describe the sociodemographic and clinical characteristics of children with multiple sclerosis. Methods: The cross-sectional study was collected data from 120 children who met the research criteria and were under follow-up at 7 hospitals in T & uuml;rkiye between August 2021 and February 2022. Ethical approval was obtained from the Medical Research Ethics Committee of Ege University. The researchers developed the "The Sociodemographic Form "used in the study by based on a comprehensive literature review and previous research experiences. The form was used according to expert opinion. Results: The study included 120 eligible patients, of whom 71.2% were girls. The mean age (+/- SD) at disease onset was 13.6 +/- 2.2 years, while the mean age at the time of the study was 15.7 +/- 1.5 years. Most of the participants were high school students (84.2%), and 53.3% resided in metropolitan areas. All participants were receiving disease-modifying therapy. The study found that 67.5% of the children had school absenteeism due to the disease. Furthermore, 75% of the children experienced supratentorial symptoms, with 50% presented with optic symptoms, and 37.5% exhibiting brainstem symptoms prior to diagnosis. Drug-related side effects were reported in 58.3% of children. Additionally,99.2% of the children received information about the disease. Furthermore, 75% of the children experienced challenges during the disease and treatment process. Among these children who encountered difficulties, 52.5% reported psychological problems, 42.5% experienced side effects due to medication, 42.5% had difficulty accessing accurate and sufficient information about disease and treatment management, 32.5% encountered social and school-related issues, and 5.8% had concerns related to the clinical environment. Conclusion: Childhood multiple sclerosis is more prevalent among girls, particularly in the relapsing-remitting form. The most commonly used treatments for pediatric multiple sclerosis include interferon beta-1a and glatiramer acetate. The findings of this study indicate that a significant proportion of participating children encountered challenges during the disease and treatment process, with more than half experiencing drug-related side effects. These challenges underscore the potential negative impact on treatment adherence in this population.Article Citation - WoS: 3Citation - Scopus: 3Characterization of Mesenchymal Stem Cells in Mucolipidosis Type Ii (i-Cell Disease)(Tubitak Scientific & Technological Research Council Turkey, 2019) Köse, Sevil; Kaya, Fatima Aerts; Kuşkonmaz, Bülent Barış; Çetinkaya, Duygu UçkanMucolipidosis type II (ML-II, I-cell disease) is a fatal inherited lysosomal storage disease caused by a deficiency of theenzyme N-acetylglucosamine-1-phosphotransferase. A characteristic skeletal phenotype is one of the many clinical manifestationsof ML-II. Since the mechanisms underlying these skeletal defects in ML-II are not completely understood, we hypothesized that adefect in osteogenic differentiation of ML-II bone marrow mesenchymal stem cells (BM-MSCs) might be responsible for this skeletalphenotype. Here, we assessed and characterized the cellular phenotype of BM-MSCs from a ML-II patient before (BBMT) and afterBM transplantation (ABMT), and we compared the results with BM-MSCs from a carrier and a healthy donor. Morphologically, wedid not observe differences in ML-II BBMT and ABMT or carrier MSCs in terms of size or granularity. Osteogenic differentiation wasnot markedly affected by disease or carrier status. Adipogenic differentiation was increased in BBMT ML-II MSCs, but chondrogenicdifferentiation was decreased in both BBMT and ABMT ML-II MSCs. Immunophenotypically no significant differences were observedbetween the samples. Interestingly, the proliferative capacity of BBMT and ABMT ML-II MSCs was increased in comparison to MSCsfrom age-matched healthy donors. These data suggest that MSCs are not likely to cause the skeletal phenotype observed in ML-II, butthey may contribute to the pathogenesis of ML-II as a result of lysosomal storage-induced pathology.Conference Object Characterizing the Position of Cio(Ieee, 2012) Cano, Carmen; Fernandez-Sanz, Luis; Misra, SanjayThis paper describes how the CIO position appear as a key role in the organizations and which are the requirements for candidates to it. We have compared the requirements presented in different studies in order to know which are the most important for a successful performance as CIO..Conference Object Characterizing the Position of Cio(Aisti-assoc Iberica Sistemas & Tecnologias informacao, 2012) Cano, Carmen; Fernandez-Sanz, Luis; Misra, Sanjay; Computer EngineeringThis paper describes how the CIO position appear as a key role in the organizations and which are the requirements for candidates to it. We have compared the requirements presented in different studies in order to know which are the most Important for a successful performance as CIO..Article Citation - WoS: 4Citation - Scopus: 4Clinical Outcomes After Transcatheter Aortic Valve Implantation in Active Cancer Patients and Cancer Survivors(Baycinar Medical Publ-baycinar Tibbi Yayincilik, 2021) Karaduman, Bilge Duran; Ayhan, Huseyin; Keles, Telat; Bozkurt, EnginBackground: In this study, we aimed to evaluate the clinical characteristics, perioperative, and mid-term outcomes of patients with severe symptomatic aortic stenosis and active cancer disease and cancer survivors undergoing transcatheter aortic valve implantation. Methods: Between December 2011 and March 2019, a total of 550 patients (248 males, 302 females; mean age: 77.6 +/- 7.9 years; range, 46 to 103 years) who underwent transcatheter aortic valve implantation for severe symptomatic aortic stenosis in our center were retrospectively analyzed. Baseline demographic characteristics, cancer type, laboratory data, procedural data, and outcome data of the patients were collected. The primary outcome measure was all-cause mortality at 30 days and every six months up to maximally available follow-up. Follow-up was performed at 30 days, six months, and 12 months after the procedure and annually thereafter. Results: Of the patients, 36 had a cancer diagnosis-active (n=10) or cured (n=26). The most common types of cancer were colorectal (16.6%), prostate (13.8%), leukemia (11.1%), and bladder (11.1%) cancers. Post-procedural complication rates were similar between the two groups. No mortality was observed in the cancer group at one month of follow-up. During follow-up, seven patients died within one year due to non-cardiac reasons. Although mortality at one year was higher in cancer patients, it did not reach statistical significance (23.3% vs. 11.6%, respectively; p=0.061). The estimated cumulative survival rate was 71.0% in the non-cancer group and 58.3% in the cancer group. The multivariate Cox regression analysis revealed that cancer was independently associated with cumulative mortality after adjusting for age, sex, body mass index, and atrial fibrillation (p=0.008). Conclusion: Our study results show that transcatheter aortic valve implantation is safe and feasible in active cancer patients and cancer survivors with similar short-term and mid-term mortality and procedure-related complication rates, compared to non-cancer patients.Article Citation - WoS: 16Citation - Scopus: 19Common Fixed Point of Generalized Rational Type Contraction Mappings in Partially Ordered Metric Spaces(Chiang Mai Univ, Fac Science, 2013) Chandok, Sumit; Karapinar, Erdal; MathematicsSome common fixed point results for generalized weak contractive condition satisfying rational type expressions in the frame work of partially ordered metric spaces are obtained. The proved results generalize and extend some known results in the literature.
