Pubmed

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14411/22

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Anti-Immigration Conspiracy Beliefs Are Associated With Endorsement of Conventional and Violent Actions Opposing Immigration and Attitudes Towards Democracy Across 21 Countries
(SpringerNature, 2025) Thomas, Emma F.; Stothard, Christina; Besta, Tomasz; Akbas, Gulcin; Becker, Julia C.; Becker, Maja; van Zomeren, Martijn; Department of Psychology; 02. School of Arts and Sciences; 01. Atılım University
Despite widespread speculation that conspiracy beliefs foster anti-democratic outcomes, the empirical picture is inconsistent. To clarify this literature, we examine the relationships that conspiracy beliefs have with commitment to reactionary action and criticism of democracy, focusing on a global issue: immigration. We expected that people who believe that their government uses immigration to diversify the population against citizens' wishes (anti-migration conspiracy beliefs) would be more committed to conventional and violent action to oppose immigration, and more critical of democracy. However, societal-level factors - economic performance and democratic functioning - were expected to influence (strengthen, weaken) these links. As hypothesized, multi-level analyses (N = 4353) from 21 countries revealed that economic prosperity attenuated the positive link between anti-migration conspiracy beliefs and commitment to reactionary action. Paradoxically, more democratic societies evidenced stronger links between conspiracy beliefs and conventional (but not violent) action to oppose immigration. Thus, more democratic societies appear to invite conventional forms of action to oppose immigration which may, in turn, weaken democratic norms of inclusion. Results highlight the interplay of individual- and societal-level factors underlying illiberal movements.
Effect of COVID-19 Infection on the Performance of Elite Adolescent Overhead Athletes
(SAGE Publications Ltd, 2025) Uluǧ, Naime; Kodak, Seyde Büşra; Kodak, Muhammed Ihsan,; Karahan, Zehra Can; Kiliç, Erden; 01. Atılım University
Background: COVID-19 might have a negative impact on sports performance. There are few studies in the literature that assess how the sports performance of adolescent athletes is affected by COVID-19. Objective: This study aimed to compare the sports performance of adolescent overhead athletes who had COVID-19 infection with those who had not. Methods: The study involved adolescent elite overhead athletes from basketball, volleyball, handball, and tennis. Athletes’ performance were assessed using core muscle endurance, hand grip strength, upper extremity functional performance, reaction time and agility performance, and the 3-min step test. Results: Study included 47 adolescent overhead athletes (mean age 15.15 ± 1.51 years). The COVID-19 group showed significantly higher Borg Scale scores and decrease in oxygen saturation levels only after the step test (p = 0.02, p = 0.02, respectively). Additionally, COVID-19 group had lower grip strength in both right and left hands compared to the non-COVID group (p = 0.01, p = 0.05, respectively). No significant association was found between core muscle power and endurance, upper extremity functional performance, reaction time and agility performance (p > 0.05). Conclusions: Our results showed reduced hand grip strength and increased fatigue following COVID-19 infection in adolescent overhead athletes. Time period after COVID-19 infection had a negative correlation with sports performance and core endurance. © 2025 Elsevier B.V., All rights reserved.
Fotorefraktif Keratektomi Sonrası Kullanılan Lotrafilcon A ve Senofilcon A Bandaj Kontakt Lenslerin Görme Rehabilitasyonu ve Oküler Konfora Etkisi
(Galenos Publ House, 2024) Alacamli, Goksu; Yakar, Konuralp; 01. Atılım University
Amaç: Fotorefraktif keratektomi (FRK) sonrası kullanılan farklı iki silikon hidrojel bandaj kontakt lensin (BKL), görsel rehabilitasyon ve oküler konfora etkisini karşılaştırmak. Gereç ve Yöntem: Bu prospektif çalışmaya, miyopi ve/veya astigmatizma kırma kusurlarını düzeltmek için iki taraflı FRK ameliyatı geçiren 30 hastanın 60 gözü dahil edildi. Ameliyat sonrası sağ göze lotrafilcon A, sol göze ise senofilcon A materyalden üretilmiş BKL uygulandı. Ameliyat sonrası 5. günde, BKL’ler çıkartıldığında, subjektif oküler rahatsızlık semptomları 0 ila 10 arası bir ölçekte değerlendirildi; burada 0, hiç rahatsızlık olmadığını ve 10, maksimum rahatsızlığı gösterdi. Ameliyat sonrası her iki gözün sferik eşdeğerleri (SE) 15. gün ve 1. ayda karşılaştırıldı. Ameliyat sonrası SE’nin ≤ ±0,50 diyoptri olması emetropi olarak kabul edildi. Emetropi elde edilen hasta sayıları da postoperatif 15. gün ve 1. ayda karşılaştırıldı. Bulgular: Ameliyat sonrası 5 günlük sürede BKL’ler arasında oküler rahatsızlık skorları anlamlı farklılık göstermedi (p>0,05). Ancak ameliyat sonrası 15. gün ve 1. aydaki SE değerleri açısından iki lens arasında istatistiksel olarak anlamlı fark gözlendi (p<0,05). Senofilcon A materyal lens takılan gözlerde ameliyat sonrası görsel rehabilitasyonun daha iyi olduğu saptandı. Sonuç: Her iki BKL arasında FRK sonrası oküler rahatsızlık skorları bakımından anlamlı fark saptanmasa da, senofilcon A materyalden üretilmiş BKL ameliyat sonrası SE hedefinde daha iyi performans gösterdi.
Gonioscopy-Assisted Transluminal Trabeculotomy Versus Bent Ab Interno Needle Goniectomy in Patients With Open-Angle Glaucoma
(Galenos Publ House, 2025) Ucgul, Ahmet Yucel; Ucgul, Rukiye Kilic; Aktas, Zeynep; Surgical Sciences; 08. Medical School; 01. Atılım University
Amaç: Açık açılı glokomlu (AAG) hastalarda gonyoskopi yardımlı translüminal trabekülotomi (GATT) ile eğik iğne ab interno gonyektominin (BANG) etkinlik ve güvenliğini karşılaştırmak. Gereç ve Yöntem: Bu retrospektif karşılaştırmalı çalışma, GATT (34 göz) veya BANG (31 göz) uygulanan AAG tanılı 65 gözü içermektedir. Göz içi basınç (GİB), başlangıçta ve postoperatif takip vizitlerinde Goldmann applanasyon tonometresi ile ölçüldü. Cerrahi başarı, kısmi (GİB ≤21 mmHg ve ≥%20 azalma) ve tam (aynı kriterler ilaçsız) olarak kategorize edildi. Komplikasyonlar ve ek cerrahi gereksinimi not edildi. Bulgular: Ameliyat öncesi ortalama GİB, GATT grubunda 32,9±6,1 mmHg iken, BANG grubunda 31,8±5,4 mmHg idi. Son kontrolde, GATT grubunda ortalama GİB 15,8±4,5 mmHg’ye düşerken (%51,9 azalma), BANG grubunda 17,9±5,7 mmHg’ye (%43,7 azalma) düştü. Tam cerrahi başarı oranı GATT prosedürü için %88,2, BANG prosedürü için %61,3’tü. Erken cerrahi başarısızlıklar BANG grubunda daha sık görülürken, GATT grubunda erken başarısızlıklar daha nadir olsa da, geç dönemde cerrahi başarısızlıklar BANG grubuna göre daha sık izlendi. Her iki prosedürde de minimal komplikasyonlar görülmüş olup; en yaygın komplikasyon ise geçici hifemaydı. Sonuç: Bu çalışmada, GATT cerrahisinin, BANG cerrahisine kıyasla daha büyük ve daha sürdürülebilir GİB azalması sağladığı ve daha yüksek cerrahi başarı oranlarına sahip olduğu dikkate alındığında, AAG’nin yönetiminde GATT’ın daha güvenilir bir seçenek olduğu söylenebilir.
A Niche-Based Perspective to Stem and Cancer Stem Cells of the Lung
(Springer, 2025) Boyacıoğlu, Özge; Kalali, Berfin Deniz; Tongün, Ege; Korkusuz, Petek; Basic Sciences; 08. Medical School; 01. Atılım University
Lungs carry the principle function for the conduction and exchange of air through the primary, secondary, tertiary bronchi, bronchioles, and alveoli, resulting in the exchange of oxygen to carbon dioxide within the human tissues. Lung stem and progenitor cells enable differentiation of parenchymal and stromal elements and provide homeostasis and regeneration in the microenvironment against pulmonary diseases. Tumor-initiating cancer cells (TICs) refer to a subpopulation named as cancer stem cells (CSCs) of lung cancer exhibiting high self-renewal and proliferation capacity by Notch, Hippo, Hedgehog, and Wnt signaling pathways that leads to tumor development or recurrence. Lung cancer stem cells (LCSCs) are characterized by distinct genotypic or phenotypic alterations compared to healthy lung stem cells (LSCs) that provide a potential target to treat lung cancer. Therefore, understanding the cascades responsible for the transformation of healthy to CSCs is essential to develop new targeted therapy approaches. In this chapter, we precisely highlight the latest researches on LSCs and CSCs, key signaling mechanisms within the perspective of novel targeted therapy strategies. © 2025 Elsevier B.V., All rights reserved.
An Updated Meta-Analysis on the Association Between Celiac Disease and Cardiovascular Diseases
(E-Century Publishing Corp, 2025) Faraji, Mahdi; Khademi, Reza; Maleki, Maede; Jafari, Fatemeh; Olama, Ensiyeh; Saghafi, Mohammad Sadra; Anar, Mahsa Asadi; 01. Atılım University
Objectives: Research on the relationship between celiac disease (CD) and cardiovascular disease (CVD) is still ongoing, and different studies have reported contradictory findings. To carry out a meta-analysis and systematic review to look into the connection between CD and CVD risk. Methods: A thorough search was conducted in PubMed, Scopus, and Google Scholar databases up to February 19, 2024. Relevant articles were extracted, and the titles, abstracts, and full texts of the related articles were screened. The quality of the studies was assessed using the Joanna Briggs Institute critical appraisal tools. Results: Nine cohort and one case-control studies involving 49,621,333 individuals were included in the meta-analysis. The pooled analysis revealed a 7% increased risk of CVD in CD patients compared to controls (OR: 1.07, 95% CI: 1.03-1.10, P < 0.05). Significant heterogeneity was observed among studies (I2 = 76%, P < 0.001). Conclusion: This meta-analysis provides evidence of a modest but significant increase in CVD risk in patients with CD. The results highlight the importance of considering cardiovascular health in CD treatment and the need for further research to elucidate the mechanisms underlying this association and to develop targeted prevention strategies.

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