Predictors of Non-Invasive Ventilation Failure and Associated Factors Among the Covid-19 Patients Admitted To Intensive Care Unit

dc.authorscopusid 57223798315
dc.authorscopusid 6603477493
dc.authorscopusid 23094932200
dc.contributor.author Varpaei,H.A.
dc.contributor.author Bayraktar,N.
dc.contributor.author Mohammadi,M.
dc.contributor.other Nursing
dc.date.accessioned 2024-07-05T15:50:20Z
dc.date.available 2024-07-05T15:50:20Z
dc.date.issued 2023
dc.department Atılım University en_US
dc.department-temp Varpaei H.A., College of Nursing, Michigan State University, East Lansing, United States; Bayraktar N., Atilim University School of Health Sciences, Nursing Department, Ankara, Turkey; Mohammadi M., Department of Critical Care, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran en_US
dc.description.abstract Background: Non-invasive ventilation (NIV) is a method of oxygenation supply that utilizes a face mask and eliminates the need for an endotracheal airway. Non-invasive ventilation failure is defined as the necessity for endotracheal intubation or death during the NIV trial. Objectives: This study aimed to identify the predictors and associated factors of NIV failure in coronavirus disease 2019 (COVID-19) patients admitted to an intensive care unit (ICU). Methods: This retrospective, longitudinal cohort study utilized electronic medical records of COVID-19 patients admitted to the ICU. A total of 150 patients were included in the study. Patient demographics, medical history, laboratory tests, partial pressure of carbon dioxide (PCO2), oxygen saturation (SpO2), heart rate, acidosis, consciousness, oxygenation, and respiratory rate (HACOR score), and the ratio of oxygen saturation (ROX) index (the SpO2/fraction of inspired oxygen [FIO2] to respiratory rate [SF] ratio) were recorded. Non-invasive ventilation failure was determined based on the need for endotracheal intubation or cardiac-respiratory arrest while on NIV. Statistical analysis was conducted using SPSS software (version 26). Results: Of the patients, 55.3% were male (mean age: 55.9 years), with an NIV failure rate of 67.3%, a mortality rate of 66.7%, and 3.3% of patients requiring tracheostomy after NIV failure. The ROX index consistently decreased over time, and an increase in the HACOR score and PCO2 after 6 hours of commencing NIV were the predictors of NIV failure. Additionally, higher levels of lactate dehydrogenase, lower SF ratios, and higher APACHE scores upon ICU admission were significantly associated with NIV failure. Notably, the erythrocyte sedimentation rate (ESR) as an inflammatory index, SF ratio upon ICU admission, HACOR score, ROX index, and PCO2 after 12 hours were significant predictors of in-hospital mortality in patients receiving NIV. Conclusions: The ROX index, HACOR scale, and PCO2 are significant predictors of both NIV failure and in-hospital mortality. © 2023, Varpaei et al. en_US
dc.identifier.citationcount 0
dc.identifier.doi 10.5812/aapm-140847
dc.identifier.issn 2228-7523
dc.identifier.issue 6 en_US
dc.identifier.scopus 2-s2.0-85179627497
dc.identifier.scopusquality Q2
dc.identifier.uri https://doi.org/10.5812/aapm-140847
dc.identifier.uri https://hdl.handle.net/20.500.14411/4133
dc.identifier.volume 13 en_US
dc.institutionauthor Bayraktar, Nurhan
dc.language.iso en en_US
dc.publisher Brieflands en_US
dc.relation.ispartof Anesthesiology and Pain Medicine en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.scopus.citedbyCount 2
dc.subject Acute Respiratory Distress Syndrome en_US
dc.subject Airway Management en_US
dc.subject Critical Care en_US
dc.subject Noninvasive Ventilation en_US
dc.subject Nursing Care en_US
dc.title Predictors of Non-Invasive Ventilation Failure and Associated Factors Among the Covid-19 Patients Admitted To Intensive Care Unit en_US
dc.type Article en_US
dspace.entity.type Publication
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