Conservative Management of Unilateral and Unilocolor Ovarian Cysts ≥ 10 Cm in Diameter in Postmenopausal Women

dc.authorscopusid 57223203724
dc.authorscopusid 56971288700
dc.authorscopusid 57223187926
dc.contributor.author Oguz,M.S.
dc.contributor.author Ecemiş,T.
dc.contributor.author Sarıyıldız,G.T.
dc.contributor.other Surgical Sciences
dc.contributor.other Anesthesia Program
dc.date.accessioned 2024-07-05T15:45:59Z
dc.date.available 2024-07-05T15:45:59Z
dc.date.issued 2021
dc.department Atılım University en_US
dc.department-temp Oguz M.S., Department of Obstetrics and Gynaecology, Medicana-Atılım University Hospital, Ankara, 06510, Turkey; Ecemiş T., Ankara, 06510, Turkey; Sarıyıldız G.T., Department of General Surgery, Medicana-Atılım University Hospital, Ankara, 06510, Turkey en_US
dc.description.abstract Objective: To evaluate and follow up the native behaviour of large ovarian cysts in postmenopausal women and establish the best approach based on advanced imaging technology. Study Design: The number of patients that were evaluated from January 2015 to September 2019 were 417. At the end of this study period, 375 patients were considered for this prospective evaluation. The patients with an ultrasound diagnosis of unilateral and unilocular ovarian cysts with regular septa ≥ 10 cm in diameter at menopause were enrolled in this study. During the follow-ups, the patients who developed irregular or thick septa, papillary formation or solid areas, exhibited any suspicious sign of malignancy in magnetic resonance imaging (MRI) results or displayed an augmentation in CA-125 levels were excluded from the study. In this study cancer antigen-125 (CA-125) values > 65 IU/mL were considered abnormal. The patients who met these criteria were followed with periodical ultrasounds and yearly MRI. Results: The 42 patients who were excluded from the study had significant morphological changes. These patients were showing an increase in CA-125 levels along with abnormal MRI findings during the follow-ups and in addition, they had surgical removal of cysts. All the significant morphological changes were detected by transvaginal ultrasounds. Postoperative histopathological diagnosis of these ovarian cysts revealed no abnormality. From 375 patient's cysts samples one hundred and twenty-five (33.3%) cysts had significantly decrease in size, one hundred and eleven (29.6%) of the cysts had spontaneous resolution and one hundred thirty-nine (37%) cysts persistently remained unchanged during the follow up period. The diameter of the cysts ranged from 10.4 to 18.4 cm. The cysts were categorized into three groups corresponding to a range of diameters i.e., 10-12.9 cm (62%), 13-15.9 cm (24.1%) and ≥ 16 cm (13.8%) respectively. The patients who showed spontaneous resolution were discontinued with the follow-ups while the rest of the patients were continued with their regular follow up examinations. Conclusion: The cysts should be monitored conservatively as long as possible before proceeding to a surgical treatment regardless of the size of the unilateral and unilocular ovarian cysts at postmenopausal period with limited oncogenic potential and without significant morphological changes. © 2021 The Authors. en_US
dc.identifier.citationcount 1
dc.identifier.doi 10.31083/j.ceog.2021.02.5523
dc.identifier.endpage 415 en_US
dc.identifier.issn 0390-6663
dc.identifier.issue 2 en_US
dc.identifier.scopus 2-s2.0-85105221206
dc.identifier.startpage 410 en_US
dc.identifier.uri https://doi.org/10.31083/j.ceog.2021.02.5523
dc.identifier.uri https://hdl.handle.net/20.500.14411/3996
dc.identifier.volume 48 en_US
dc.identifier.wosquality Q4
dc.institutionauthor Oğuz, Mehmet Serdar
dc.institutionauthor Sarıyıldız, Gülçin Türkmen
dc.language.iso en en_US
dc.publisher IMR Press Limited en_US
dc.relation.ispartof Clinical and Experimental Obstetrics and Gynecology en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.scopus.citedbyCount 2
dc.subject Cyst morphology and size en_US
dc.subject Ovarian cysts en_US
dc.subject Postmenopausal period en_US
dc.title Conservative Management of Unilateral and Unilocolor Ovarian Cysts ≥ 10 Cm in Diameter in Postmenopausal Women en_US
dc.type Article en_US
dspace.entity.type Publication
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