Gülen, Merter
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Name Variants
Merter, Gülen
M.,Gülen
Merter, Gulen
M.,Gulen
Gülen,M.
Gulen M.
M., Gulen
Gulen,M.
G., Merter
G.,Merter
Gulen, M
Gulen, Merter
Gülen, Merter
M., Gülen
M.,Gülen
Merter, Gulen
M.,Gulen
Gülen,M.
Gulen M.
M., Gulen
Gulen,M.
G., Merter
G.,Merter
Gulen, M
Gulen, Merter
Gülen, Merter
M., Gülen
Job Title
Doktor Öğretim Üyesi
Email Address
merter.gulen@atilim.edu.tr
Main Affiliation
Surgical Sciences
Status
Website
ORCID ID
Scopus Author ID
Turkish CoHE Profile ID
Google Scholar ID
WoS Researcher ID
Sustainable Development Goals
SDG data is not available
Scholarly Output
9
Articles
7
Citation Count
0
Supervised Theses
0
9 results
Scholarly Output Search Results
Now showing 1 - 9 of 9
Article Citation - Scopus: 1Effects of Carbon Dioxide Pneumoperitoneum on Renal Function in Obstructive Jaundice: an Experimental Study in a Rat Model(Asoc Regional Dialisis Trasplantes Renales, 2023) Gulen, Merter; Sare, Mustafa; Kozan, Ramazan; Yuksel, Seher; Deger, Serpil Muge; Senes, Mehmet; Cayci, Ayse Banu; Surgical SciencesIntroduction: Both pneumoperitoneum (PNP) and obstructive jaundice (OJ) are known to lead to acute kidney injury (AKI) potentially, but the combined effect has not been investigated. Aim: This study aimed to investigate the effects of PNP on renal functions in a rat model of OJ. Methods: We divided forty-eight rats into eight groups of six rats. Group 1 was the control (sham-operated) group; Groups 2, 3, and 4 were induced 5, 10, and 15 mmHg of CO2 PNP, respectively (Groups 1-4: "non-OJ Groups"); Group 5 was the OJ group; and Groups 6, 7 and 8 were OJ groups that were induced with 5, 10, and 15 mmHg CO2 PNP was respectively (Groups 5-8: "OJ Groups"). The common bile duct was ligated and divided into OJ Groups. After 48 hours, a 5-10-15 mmHg PNP was induced by mini-laparotomy with a Veress needle in Groups 6, 7, and 8, maintained for 60 minutes. Results: There were no statistically significant differences between groups regarding blood urea Nitrogen and Creatinin levels (p> 0.05). Neutrophil gelatinase-associated lipocalin (NGAL) values were significantly higher in OJ Groups than in non-OJ Groups (p< 0.05). Serum Cystatin-C values were significantly higher in OJ Groups with 10 and 15 mmHg PNP than in nonOJ Groups (p< 0.05). Conclusion: In the early stage of AKI, NGAL and Cystatin-C levels might be higher, while standard renal function tests were normal. Our findings highlight the apparent unfavorable effect of OJ with PNP on renal functions and early recognition of AKI with the measurement of NGAL and Cystatin-C in these conditions.Editorial Preface(IGI Global, 2020) Esiyok, E.; Surgical SciencesArticle Importance of Alkaline Phosphatase as a Predictor of Transient Hypoparathyroidism After Parathyroidectomy(Springernature, 2025) Gulen, Merter; Emral, Ahmet Cihangir; Sariyildiz, Gulcin Turkmen; Surgical Sciences; Anesthesia ProgramBackgroundThere are insufficient studies that have investigated the relationship between temporary hypoparathyroidism (hypoPTH) and the preoperative serum alkaline phosphatase (ALP) level in patients with no renal function disorder who have undergone isolated parathyroidectomy. The aim of this study was to determine whether or not the preoperative serum ALP level could be a marker which could predict the development of postoperative temporary hypoPTH. MethodsThis cross-sectional study included 158 patients aged > 18 years who were diagnosed with primary hyperparathyroidism (PHPT) between 2017 and 2022. The demographic data of the patients were retrieved from the hospital records. The patients were separated into two groups according to the serum calcium level after the parathyroidectomy, as the normal group and the temporary hypoPTH group. The determinants of temporary hypoPTH developing after parathyroidectomy in PHPT patients were investigated using multivariate logistic regression analysis. ResultsTemporary hypoPTH was determined in 25.3% of patients. The mean age and 25-O-HD level were determined to be lower in the patients who developed temporary hypoPTH compared to those who did not. The preoperative serum ALP, parathormone, and 24-h urine calcium levels were determined to be higher in the cases that developed temporary hypoPTH. As a result of the regression analysis, only the serum ALP level was determined to be an independent risk factor predicting the development of temporary hypoPTH (p: 0.005, OR: 1.021). In the ROC analysis, when a cutoff value of 119.5 pg/mL was taken for ALP, it was determined to have 73% sensitivity and 72% specificity for the prediction of the development of temporary hypoPTH. ConclusionsThe most appropriate treatment for symptomatic PHPT patients selected with positive imaging is minimally invasive parathyroidectomy. The most important postoperative complications are hypocalcemia and hypoPTH. The preoperative serum ALP level may be helpful in determining patients at risk of developing temporary hypoPTH following parathyroidectomy.Article Böbrek Naklinde de Novo Uzamış Salınımlı Takrolimus Kullanımı Sonuçları: Tek Merkez, 1 Yıllık Sonuçlar(2022) Sarıyıldız, Gülçin Türkmen; Demir, Mehmet Emin; Sezer, Siren; Sozener, Ulas; Ercan, Zafer; Gulen, Merter; Özşeker, Fatma Necla; Anesthesia Program; Surgical SciencesAmaç: Böbrek nakli alıcılarında günde tek doz uzamış salınımlı takrolimus (tac-ER) kullanımı, erken salınımlı takrolimus (tac-IR) kullanımına benzer etkinlik ve daha iyi ilaç uyumu sağlaması amacıyla geliştirilmiştir. Ancak uzamış salınımlı takrolimus ile ilgili deneyimler daha çok nakil sonrası dönemde yapılan “switch” protokollerine dayanmaktadır. Bu çalışmada böbrek alıcılarında de novo tac-ER kullanımı ile ilgili deneyimlerimizi ve 1 yıllık sonuçları sunmayı amaçladık. Gereç ve Yöntem: Bu tek merkezli retrospektif çalışmaya Ocak 2022-Ocak 2021 arasında yapılan 72 de novo böbrek nakli hastası dahil edilmiştir. Hastalar tac- ER ve tac-IR alan iki gruba ayrıldı. Bir yıllık allogreft fonksiyonları ve sağ kalımları, hastaların günlük ilaç dozları ve bunların akut rejeksiyon atakları ile ilişkileri karşılaştırıldı. Allogreft fonksiyonları ve akut rejeksiyon atakları üzerine etki eden faktörler incelendi. Bulgular: Toplam 69 hastanın (uzamış salınımlı grupta 30 hasta ve erken salınımlı grupta 39 hasta) verileri incelendi. Üç hasta posttransplant erken dönemde öldüğü için analize dahil edilmedi. Nakil sonrası 12 aylık izlem boyunca her iki grup arasında serum kreatinin ve takrolimus çukur değerler bencer bulundu (p>0,05). İlk 3 ay içinde hedef takrolimus değerlere ulaşmak için, tac-ER grubunda daha yüksek günlük dozlar (milligra/gün ve milligram/gün/kg) gerekti (p<0,05). Nakil sonrası ilk 12 ay içinde her iki grupta da rejeksiyon oranları benzerdi (p=0,281). Tek değişkenli analizde posttransplant 1. aydaki takrolimus dozu (milligram/kg/gün) takrolimus çukur değerinin aksine rejeksiyon gelişimi üzerinde etkili görüldü (p=0,02). Sonuç: Böbrek naklinde uzamış salınımlı takrolimusun (Advagraf®) de novo kullanımı, erken salınımlı takrolimus kullanımına benzer etkinlik, allogreft sağ kalımı ve fonksiyonu sağlar.Article Fistulectomy and Primary Sphincteroplasty for Transsphincteric Fistula(Coll Physicians & Surgeons Pakistan, 2025) Emral, Ahmet Cihangir; Gulen, Merter; Ege, Bahadir; Surgical SciencesObjective: To evaluate the results of patients treated with fistulectomy and primary sphincteroplasty for uncomplicated perianal fistula. Study Design: Observational study. Place and Duration of the Study: Medicana International Hospital affiliated with Atilim University, Faculty of Medicine, Ankara, Turkiye, from January 2020 to September 2023. Methodology: In this study, patients who were operated on for perianal fistula between 2020 and 2023 were retrospectively examined. Data were obtained retrospectively. All patients underwent preoperative perianal MRI. Clinical notes were evaluated with the Cleveland Clinic Incontinence Score (CCIS) by physical examination. All patients were followed up on the first postoperative day, 1st week, 1st and 3rd postoperative months. Results: A total of 44 patients who underwent fistulectomy with primary sphincteroplasty were included in the study. Twenty-six patients (59.1%) had a history of perianal abscesses. It was observed that 34 (77.3%) of the patients had posterior, 7 (15.9%) anterior, and 3 (6.8%) lateral fistulas. A total of 3 patients (6.8%) were observed to have minor worsening in their incontinence scores. There was no statistically significant difference between the preoperative and postoperative 3rd month Cleveland Clinic Incontinence Score values of the patients (CCIS mean 1.6 vs. 1.7, respectively, p >0.05). Recurrence was observed in 1 patient (2.3%) during follow-ups. Conclusion: Fistulectomy with primary sphincteroplasty is an effective and reliable method to preserve anal continence and improve quality of life.Article Which Technique Is Preferable for Grade 2-3 Hemorrhoidal Disease: Laser Vs. Rubber Band Ligation ? A Retrospective Study(Springernature, 2025) Emral, Ahmet Cihangir; Gulen, Merter; Ege, Bahadir; Surgical SciencesBackground The aim of this study is to compare the short and long-term results (postoperative pain, complications, return to daily life, recurrence) between patients who underwent laser hemorrhoidoplasty (LH) and rubber band ligation (RBL) due to grade 2-3 hemorrhoidal disease. Methods The results of patients who underwent LH and RBL between June 2020 and June 2023 for grade 2-3 hemorrhoidal disease were evaluated retrospectively. The patient information was examined in terms of operation time, postoperative 1st, 7th and 14th day visual analog scale (VAS) values, the amount of analgesic used in the first 7 postoperative days, return to normal life (days), recurrence within 1 year and other complications (postoperative bleeding, thrombosis, urinary retention, infection/abscess, anal stenosis, deterioration in continence). Results A total of 260 patients were included in the study, 166 of whom underwent RBL and 94 LH. Operation time, VAS values, postoperative 7-day analgesic use (mg), worsening of incontinence, time to return to normal life (days), complications and recurrence within 1 year evaluated. LH has statistically significant lower postoperative 1st day pain and less analgesic use (mg) than RBL (p < 0.001). Conclus & imath;ons LH and RBL both offer effective treatment options for grade 2-3 hemorrhoidal disease, with comparable recurrence rates and time to return to normal life. However, LH is associated with significantly less postoperative pain and analgesic use on the first postoperative day, potentially enhancing patient satisfaction.Article Hemoroid Lastik Band Ligasyonu Komplikasyonlarının Yönetimi: Masif Rektal Kanama(Galenos Publ House, 2024) Gülen, Merter; Emral, Ahmet Cihangir; Ege, Bahadır; Surgical SciencesAmaç: Çalışmanın amacı, hemoroidal hastalıkta cerrahi dışı tedavi seçeneklerinden biri olan lastik band ligasyonunu (RBL) ve buna bağlı gelişen komplikasyonları irdelemektir. Morbiditesi nedeniyle önem arz eden masif rektal kanama komplikasyonunun yönetimini sunmaktır. Gereç ve Yöntem: Evre 1-2 ve 3 internal hemoroidal hastalık nedeniyle 2018-2022 yılları arasında kliniğimizde RBL yapılan 564 hasta retrospektif olarak irdelenmiştir. Gebelik durumu, geçirilmiş anorektal cerrahi, kronik karaciğer hastalığı ve antikoagülan kullanımı nedeniyle 72 hasta çalışma dışında bırakılmıştır. Hastaların 492’si çalışmaya dahil edilmiştir. Tüm hastalara proktoloji ünitesinde detaylı anorektal muayene, 50 yaş üstündekilere ise kolonoskopik değerlendirme yapılmıştır. Hastaların demografik özellikleri, gelişen komplikasyonlar (minör/majör) ve uygulanan band ligasyon sayısı standardize edilmiş formlara kayıt edildi. Bulgular: Hastaların ortalama yaşı 33,4±11 (18-65) yıl olup, 385’i (%78,3) erkek, 107’si (%21,7) kadındı. Hastaların 39’una (%8) tek kadran, 448 hastaya (%91) iki kadran ve 5 hastaya üç kadran RBL uygulandı. RBL sonrası minör komplikasyonlar (anal ağrı, vazovagal semptomlar, minör rektal kanama, üriner retansiyon) yirmi hastada (%4) gelişirken, hastaların 4’ünde (%0,8) masif rektal kanama meydana gelmiştir. Masif rektal kanama gelişen hastaların hepsi acil şartlarda hospitalize edildi ve operasyona alındı. Bu hastaların birine 3 ünite, üç hastaya ise 4 ünite eritrosit transfüzyonu yapıldı. Sonuç: Hemoroidal band ligasyonu, hemoroidal hastalık tedavisinde güvenli ve etkili bir yöntemdir. Ancak hayatı tehdit edecek ciddi kanamalara yol açabileceği göz önünde bulundurulmalıdır.Conference Object Citation - WoS: 1Secure Communication Tests Carried Out With Next Generation Narrow Band Terminal in Satellite and Local Area Networks(Ieee, 2013) Dilli, Orkun; Akcam, Nursel; Koyuncu, Murat; Oguslu, Ender; Surgical Sciences; Information Systems EngineeringCommunication becomes more and more important day by day and especially secure communication from one end to the other holds a vital place in our daily life. Developed countries which are aware of this fact has started to carry out serious studies on secure communication from one end to the other. One of the most important studies is the project which appeared as FNBDT (Future Narrow Band Digital Terminal) at first and was renamed as SCIP (Secure Communication Interoperability Protocol) later on. FNBDT (Future Narrow Band Digital Terminal) or SCIP (Secure Communication Interoperability Protocol) is a communication protocol which is a result of secure communication need of different network devices in contact with each other. The main purpose of the protocol is to provide the new generation terminals which are source of transmission with secure communication with each other through different networks using narrow band. National and international studies on FNBDT/SCIP has focused on three main points; FNBDT protocol, SCIP protocol and codes of MELP (Mixed Excitation Linear Prediction) Studies about implementation of FNBDT/SCIP are much fewer than theoretical studies on the matter. Some tests of FNBDT/SCIP on satellite and local Networks are carried out to overcome this lack of implementation. It is aimed to set up calls on different Networks, to check transmission of voice and data with and without any loss and to find out the limits with these tests. Results of these tests were declared before. In this study, some tests on satellite and local Networks are carried out; as a result, values about call set ups and limits of voice and data transmission are compared with ITU (International Telecommunications Union) standards.Article Citation - WoS: 1Citation - Scopus: 1Evaluating Efficacy and Outcomes: Comparison of Laser Treatment and Crystallized Phenol in Pilonidal Sinus Disease(Frontiers Media Sa, 2025) Emral, Ahmet Cihangir; Gulen, Merter; Ege, Bahadir; Surgical SciencesObjective The aim of this study is to comprehensively evaluate the efficacy of laser ablation and crystallized phenol application in the treatment of pilonidal sinus disease, focusing on treatment success, recurrence rates, complications, and the patients' return to normal life.Material and method Data from patients treated for pilonidal sinus disease with laser ablation and crystallized phenol application at our clinic between January 2020 and September 2023 were retrospectively reviewed. Preoperative data including pit counts, disease stage, preoperative pilonidal abscess history, disease duration (week), treatment success, recurrence/persistent disease, postoperative complications, healing time (days), and visual analogue scale (VAS) scores on postoperative days 1 and 7, as well as return to normal life (days), were analyzed.Results A total of 121 patients were included in the study, with 51 receiving laser ablation and 70 receiving crystallized phenol application. The postoperative outcomes revealed that the wound healing period and postoperative VAS values were statistically significantly better in the laser ablation group.Conclusion Wound healing was faster and postoperative pain was less in the laser group compared to the phenol group. According to this study, both methods can successfully treat the disease in selected cases.
