Mıshra, AlokAbdalla, ReemMishra, AlokSoftware Engineering2024-07-052024-07-05201811311-97021314-408110.2478/cait-2018-00332-s2.0-85051064161https://doi.org/10.2478/cait-2018-0033https://hdl.handle.net/20.500.14411/3008Mishra, Alok/0000-0003-1275-2050This paper carries out a comparative analysis to determine the advantages and the stages of two agent-based methodologies: Multi-agent Systems Engineering (MaSE) methodology, which is designed specifically for an agent-based and complete lifecycle approach, while also being appropriate for understanding and developing complex open systems; Agent Systems Methodology (ASEME) suggests a modular Multi-Agent System (MAS) development approach and uses the concept of intra-agent control. We also examine the strengths and weaknesses of these methodologies and the dependencies between their models and their processes. Both methodologies are applied to develop The Guardian Angle: Patient-Centered Health Information System (GA: PCHIS), which is an example of agent-based applications used to improve health care information systems.eninfo:eu-repo/semantics/openAccessAgent-based MethodologiesMaSEASEMEArticleQ2182123132WOS:000436378800010