Özkan, OzanOzkan, OzanSasmazel, Hilal TurkogluŞaşmazel, Hilal TürkoğluMetallurgical and Materials Engineering2024-07-052024-07-05201850885-32821530-802210.1177/08853282187555712-s2.0-85044382911https://doi.org/10.1177/0885328218755571https://hdl.handle.net/20.500.14411/2676Turkoglu Sasmazel, Hilal/0000-0002-0254-4541; Ozkan, Ozan/0000-0002-9050-1583In this study, dry air plasma jet and dielectric barrier discharge Ar+O-2 or Ar+N-2 plasma modifications and their effects on wettability, topography, functionality and biological efficiency of the hybrid polymeric poly (epsilon-caprolactone)/chitosan scaffolds were reported. The samples treated with Ar+O-2 dielectric barrier discharge plasma (80 sccm O-2 flow rate, 3-min treatment) or with dry air plasma jet (15-cm nozzle-sample distance, 13-min treatment) had the closest wettability (49.11 +/- 1.83 and 53.60 +/- 0.95, respectively) to the commercial tissue culture polystyrene used for cell cultivation. Scanning electron microscopy images and X-ray photoelectron spectrometry analysis showed increase in topographical roughness and OH/NH2 functionality, respectively. Increased fluid uptake capacity for the scaffolds treated with Ar+O-2 dielectric barrier discharge plasma (73.60%+/- 1.78) and dry air plasma jet (72.48%+/- 0.75) were also noted. Finally, initial cell attachment as well as seven-day cell viability, growth and proliferation performances were found to be significantly better for both plasma treated scaffolds than for untreated scaffolds.eninfo:eu-repo/semantics/closedAccessDielectric barrier dischargehybrid poly(epsilon-caprolactone)chitosan scaffoldsMRC5 fibroblast cellsplasma jetplasma treatmentArticleQ332913001313WOS:00042986150001429388455