Yugeswaran, S.Kobayashi, A.Ucisik, A. HikmetSubramanian, B.2024-07-052024-07-0520150169-43321873-558410.1016/j.apsusc.2015.04.0362-s2.0-84931403162https://doi.org/10.1016/j.apsusc.2015.04.036https://hdl.handle.net/20.500.14411/857SUBRAMANIAM, DR.YUGESWARAN/0000-0002-5165-8094Hydroxyapatite (HA) can be coated onto metal implants as a ceramic biocompatible coating to bridge the growth between implants and human tissue. Meanwhile many efforts have been made to improve the mechanical properties of the HA coatings without affecting its bioactivity. In the present study, nanostructure titania (TiO2) was mixed with HA powder and HA-nanostructure TiO2 composite coatings were produced by gas tunnel type plasma spraying torch under optimized spraying conditions. For this purpose, composition of 10 wt% TiO2 + 90 wt% HA, 20 wt% TiO2 + 80 wt% HA and 30 wt% TiO2 + 70 wt% HA were selected as the feedstock materials. The phase, microstructure and mechanical properties of the coatings were characterized. The obtained results validated that the increase in weight percentage of nanostructure TiO2 in HA coating significantly increased the microhardness, adhesive strength and wear resistance of the coatings. Analysis of the in vitro bioactivity and cytocompatibility of the coatings were done using conventional simulated body fluid (c-SBF) solution and cultured green fluorescent protein (GFP) labeled marrow stromal cells (MSCs) respectively. The bioactivity results revealed that the composite coating has bio-active surface with good cytocompatibility. (C) 2015 Elsevier B.V. All rights reserved.eninfo:eu-repo/semantics/closedAccessHydroxyapatiteNanostructureTitaniaPlasma sprayMechanical propertiesBioactivityArticleQ13474856WOS:00035605850000733