Seker, Elif DilaraYavuz, IbrahimYucesoy, TurkerCenkci, EbruYay, Arzu2024-07-052024-07-05202251049-22751536-373210.1097/SCS.00000000000078372-s2.0-85122744909https://doi.org/10.1097/SCS.0000000000007837https://hdl.handle.net/20.500.14411/1644YUCESOY, TURKER/0000-0002-1356-1574;Purpose: To evaluate the effects of 2 different surface roughness values produced by sandblasted, large-grit, and acid-etched treatments at different loading conditions on the stability of mini-screws. Material and Methods: A total of 56 mini-screws (Group 1; 28 with Ra value of 1 mm, Group 2; 28 with Ra value of 1.5 mu m) were inserted into the tibia of fourteen New Zealand rabbits. Surface analysis was performed before the placement of the miniscrews using multi-technique characterization. The mini-screws were loaded with 500 grf after different healing times: unloaded, immediate, 4 and 8 weeks. Resonance frequency analyses were performed immediately after mini-screw placement and at the end of loading. Biomechanical and histomorphometric analyses were also performed at the end of the loading period. Results: All mini-screws preserved their stability at the end of the loading period. However, the resonance frequency analyses showed higher implant stability quotient scores for 8-week group, unlike the immediate loading and unloaded groups (P < 0.05). According to the infinite focus microscopy results, prolongation of healing time resulted in a greater bone area on the loaded mini-screws in Group 2 (P < 0.05). Similarly, the histomorphometric analysis revealed higher bone-to-implant contact values in the 8-week group. There was no significant difference in the stability between the miniscrews with the Ra values of 1 and 1.5 mu m. Conclusions: Sandblasted, large-grit, and acid-etched treated miniscrews showed significantly higher stability with healing time under heavy forces. Sandblasted, large-grit, and acid-etched treated miniscrews can be removed without fracture of the screw or the bone surfaces.eninfo:eu-repo/semantics/closedAccessBone implant interactionsorthodonticssurface chemistryArticleQ4Q33314147WOS:00073548240002734267129