Ay,A.Boztepe,H.Özbay,S.Ç.Yılmaz,P.Karadavut,B.Burhanoğulları,D.Akyüz,C.Nursing2024-07-052024-07-05202300882-596310.1016/j.pedn.2023.10.0112-s2.0-85173864684https://doi.org/10.1016/j.pedn.2023.10.011https://hdl.handle.net/20.500.14411/4113Purpose: We evaluated the factors affecting chemotherapy-induced nausea and vomiting (CINV) in children with cancer. Design and methods: This cross-sectional study was conducted with 62 children aged 9 to 18 years old with a solid tumor who received chemotherapy for the first time, and their parents. Data were collected using a data collection form, the State-Trait Anxiety Inventory for Children, the Beck Anxiety Inventory, the Spielberger State-Trait Anxiety Inventory, and the Baxter Retching Faces Scale. Data were analyzed using Spearman's correlation and logistic regression analyses. Results: Risk factors related to the child, treatment, and parent were examined. Child-related factors were determined as diagnosis (odds ratio [OR] = 5.5), time since diagnosis (OR = 1.9, OR = 4.7), pretreatment anxiety of the child (r = 0.439, r = 0.422), and past experience of nausea and vomiting before treatment (OR = 1.2). Treatment-related factors involved anti-emetic prophylaxis (OR = 4.9, OR = 9.2). Parent-related factors included pretreatment anxiety of the parent (r = 0.271, r = 0.287), accommodation (OR = 5.5), not eating (OR = 1.2, OR = 1.3), and bad smell (OR = 1.2), which were described amongst parents' as factors that trigger CINV. Conclusions: The occurrence of CINV is significantly affected by child-, treatment-, and parent-related risk factors. Practice implications: Pediatric nurses should create an environment for children and their parents to reduce their anxiety and provide basic knowledge and skills about the management of CINV. © 2023 Elsevier Inc.eninfo:eu-repo/semantics/closedAccessAffecting factorsChemotherapyChildrenNausea and vomitingPediatric oncology nursingArticleQ273e426e434PubMed:37845092