Sarigul, NeslihanKurultak, IlhanGokceoglu, Arife UsluKorkmaz, FilizPhysics Group2024-07-052024-07-052021191864-063X1864-064810.1002/jbio.2021000092-s2.0-85103624538https://doi.org/10.1002/jbio.202100009https://hdl.handle.net/20.500.14411/2054Uslu Gökceoğlu, Arife/0000-0002-5331-0315; Korkmaz, Filiz/0000-0003-3512-3521; kurultak, ilhan/0000-0001-5607-1375; SARIGUL, NESLIHAN/0000-0002-5371-7924Urine spectra from 108 healthy volunteers are studied by attenuated total refraction-Fourier transform infrared (ATR-FTIR) spectroscopy. The spectral features are correlated with observable urine components. The variation of spectra within a healthy population is quantified and a library of reference spectra is constructed. Using the band assignments, these spectra are compared with both age-wise and gender-wise. Children show the least intensity variations compared to both adult groups. Young adults show the highest variation, particularly in the 1650 to 1400 cm(-1) and 1200 to 900 cm(-1) regions. These results indicate the importance of the size of the control group in comparative studies utilizing FTIR. Age-wise comparisons reveal that phosphate and sulfate excretion decreases with age, and that the variance of phosphate among individuals is higher with adults. As for gender-wise comparisons, females show a slightly higher citrate content at 1390 cm(-1) regardless of the age and they show a higher variance in the 1200 to 1000 cm(-1) region when compared to men.eninfo:eu-repo/semantics/closedAccessadult urineband assignmentchildren urineFTIRnormal variationurine spectrumArticleQ2Q2147WOS:00063745370000133768707