Cetin, BarbarosOner, S. DoganBaranoglu, BesimManufacturing Engineering2024-07-052024-07-052017190173-08351522-268310.1002/elps.2016004612-s2.0-85013640736https://doi.org/10.1002/elps.201600461https://hdl.handle.net/20.500.14411/2865Baranoglu, Besim/0000-0003-2005-050X; Cetin, Barbaros/0000-0001-9824-4000; Cetin, Barbaros/0000-0001-9824-4000Dielectrophoresis (DEP) is a very popular technique for microfluidic bio-particle manipulation. For the design of a DEP-based microfluidic device, simulation of the particle trajectory within the microchannel network is crucial. There are basically two approaches: (i) point-particle approach and (ii) finite-sized particle approach. In this study, many aspects of both approaches are discussed for the simulation of direct current DEP, alternating current DEP, and traveling-wave DEP applications. Point-particle approach is implemented using Lagrangian tracking method, and finite-sized particle is implemented using boundary element method. The comparison of the point-particle approach and finite-sized particle approach is presented for different DEP applications. Moreover, the effect of particle-particle interaction is explored by simulating the motion of closely packed multiple particles for the same applications, and anomalous-DEP, which is a result of particle-wall interaction at the close vicinity of electrode surface, is illustrated.eninfo:eu-repo/semantics/closedAccessBoundary element methodDielectrophoresisLagrangian tracking methodMicrofluidicsArticleQ2381114071418WOS:00040262240000228164365