Agar, MehmetGulcek, IlhamKalkan, MuhammedUlutas, HakkiCelik, Muhammet RehaAksu, AhmetCakmak, Muharrem2025-06-052025-06-0520251010-660X1648-914410.3390/medicina610406412-s2.0-105003565847https://doi.org/10.3390/medicina61040641https://hdl.handle.net/20.500.14411/10590Background and Objectives: Non-intubated uniportal video-assisted thoracoscopic surgery (NI-UniVATS) is a minimally invasive technique performed using a single port, allowing the entire surgical procedure to be completed with spontaneous breathing without the need for general anesthesia. Materials and Methods: This retrospective study included 51 patients who underwent NI-UniVATS between 2020 and 2023. The intraoperative and postoperative data of patients who underwent NI-UniVATS were evaluated. Results: Among the cases, 37 (72.5%) were male, and 14 (46.6%) were female, with a mean age of 47.73 +/- 20.43 years (range: 18-78 years). The mean operative time was 25.92 +/- 7.31 min. No perioperative complications were observed in any patient. The mean postoperative hospital stay was 4.17 +/- 1.76 days (range: 2-9 days). A right hemithoracic approach was performed in 28 patients (54.9%), whereas a left hemithoracic approach was used in 23 patients (45.1%). The procedures performed included wedge resection in 27 patients (52.9%), biopsy in 22 patients (43.1%), pericardial window creation in one patient (2%), and intrathoracic foreign body removal in one patient (2%). Conclusions: NI-UniVATS allows for safer surgery by preventing the adverse effects and complications associated with general anesthesia. NI-UniVATS can be recommended as a safe and feasible approach for both minor and major thoracic procedures.eninfo:eu-repo/semantics/closedAccessNi-UnivatsNon-IntubatedMinimally InvasiveUniportalVideo-Assisted Thoracoscopic SurgeryArticleQ3Q1614WOS:00147538320000140282931