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  • Editorial
    Citation - WoS: 47
    Citation - Scopus: 47
    Emergency Changes in International Guidelines on Treatment for Head and Neck Cancer Patients During the Covid-19 Pandemic
    (Elsevier, 2020) Chaves, Aline Lauda Freitas; Castro, Ana Ferreira; Marta, Gustavo Nader; Junior, Gilberto Castro; Ferris, Robert L.; Giglio, Raul Eduardo; Kowalski, Luiz Paulo
    [No Abstract Available]
  • Article
    Citation - WoS: 5
    Citation - Scopus: 7
    G-Csf Treatment of Healthy Pediatric Donors Affects Their Hematopoietic Microenvironment Through Changes in Bone Marrow Plasma Cytokines and Stromal Cells
    (Academic Press Ltd- Elsevier Science Ltd, 2021) Aerts-Kaya, Fatima; Kilic, Emine; Kose, Sevil; Aydin, Gozde; Cagnan, Ilgin; Kuskonmaz, Baris; Uckan-Cetinkaya, Duygu
    Although G-CSF mobilized peripheral blood stem cell (PBSC) transplantation is commonly used in adults, bone marrow (BM) is still the preferred stem cell source in pediatric stem cell transplantation. Despite the fact that G-CSF is increasingly being used to enhance the hematopoietic stem/progenitor cell (HSPC) yield in BM transplantation (G-BM), the direct effects of G-CSF on the pediatric BM microenvironment have never been investigated. The BM hematopoietic niche provides the physical space where the HSPCs reside. This BM niche regulates HSPC quiescence and proliferation through direct interactions with other niche cells, including Mesenchymal Stromal Cells (MSCs). These cells have been shown to secrete a wide range of hematopoietic cytokines (CKs) and growth factors (GFs) involved in differentiation, retention and homing of hematopoietic cells. Here, we assessed changes in the BM microenvironment by measuring levels of 48 different CKs and GFs in G-BM and control BM (C-BM) plasma from pediatric donors. In addition, the effect of G-CSF on cell numbers and characteristics of HSPCs and MSCs was assessed. IL-16, SCGF-b, MIP-1b (all >1000 pg/mL) and RANTES (>10.000 pg/mL) were highly expressed in healthy donor pediatric BM plasma. Levels of IL-3, IL-18, GROa, MCP-3 (p<0.05) were increased in G-BM, whereas levels of RANTES (p<0.001) decreased after G-CSF treatment. We found a negative correlation with increasing age for IL2-Ra and LIF (p<0.05). In addition, a concomitant increase in the number of both hematopoietic and fibroblast colony forming units was observed, indicating that G-CSF affects both HSPC and MSC numbers. In conclusion, G-CSF treatment of healthy pediatric donors affects the hematopoietic BM microenvironment by expansion of HSPC and MSC numbers and modifying local CK and GF levels.
  • Article
    Citation - WoS: 6
    Citation - Scopus: 6
    Gold and Ytterbium Interfacing Effects on the Properties of the Cdse/Yb Nanosandwiched Structures
    (Elsevier Science Bv, 2018) Alharbi, S. R.; Qasrawi, A. F.
    Owing to the performance of the CdSe as an optoelectronic material used for the production of quantum dots, photosensors and wave traps we here, in this article, report the enhancements in structural and electrical properties that arises from the nanosandwiching of a 40 nm thick Yb film between two films of CdSe (CYbC-40). The CdSe films which were deposited onto glass, Yb and Au substrates are characterized by X-ray diffraction, temperature dependent electrical conductivity and impedance spectroscopy measurements in the frequency range of 10-1800 MHz. The analysis of the XRD patterns have shown that the glass/CdSe/Yb/CdSe films exhibit larger grain size and lower strain, defect density and lower stacking faults compared to the not sandwiched CdSe. In addition, it was observed that the Yb shifts the donor states of the n-type CdSe from 0.44 to 0.29 eV leading to a modification in the built in voltage of the material. On the other hand, the design of the energy band diagram has shown the ability of the formation of the Au/CYbC-40/Yb as Schottky (SB) and the Au/CYbC-40/Au as back to back Schottky barriers (BBSB). While the SB device show low band pass filter characteristics, the BBSB device performed as band stop filters. The BBSB device exhibited negative capacitance effects with filtering features that reveal a return loss of 42 dB at similar to 1440 MHz.
  • Article
    Citation - WoS: 29
    Citation - Scopus: 36
    Fixed Point Results on a Class of Generalized Metric Spaces
    (Springer Heidelberg, 2012) Aydi, Hassen; Karapinar, Erdal; Lakzian, Hossein
    Brianciari ('A fixed point theorem of Banach-Caccioppoli type on a class of generalized metric spaces,' Publ. Math. Debrecen 57 (2000) 31-37) initiated the notion of the generalized metric space as a generalization of a metric space in such a way that the triangle inequality is replaced by the 'quadrilateral inequality,' d(x, y) <= d(x, a) + d(a, b) + d(b, y) for all pairwise distinct points x, y, a, and b of X. In this paper, we establish a fixed point result for weak contractive mappings T : X -> X in complete Hausdorff generalized metric spaces. The obtained result is an extension and a generalization of many existing results in the literature.
  • Article
    Citation - WoS: 3
    Citation - Scopus: 6
    Adult Education as a Stepping-Stone To Better Jobs: an Analysis of the Adult Education Survey in Turkey
    (Sage Publications inc, 2018) Cilasun, Seyit Mumin; Demir-Seker, Sirma; Dincer, N. Nergiz; Tekin-Koru, Ayca
    The objective of this article is to investigate whether adult education (AE) can be used as a tool in facilitating transitions to/in the labor market, using the cross-sectional Adult Education Survey of Turkey (2012). AE is defined as the nonformal education for individuals aged older than 25 years. The outcome of AE is measured by changing jobs for employed and finding a job for the unemployed. Concentrating on employed people, we analyze both the determinants and the outcome of participation in AE for the purpose of changing jobs; and second, concentrating on unemployed people, we analyze both the determinants and the outcome of participation in AE for the purpose of getting employed. We find that once young males who are already working participate in AE for changing work, independent of their education or how AE is financed, they can be successful in doing so. The results of the paper suggest that AE programs offered by the government can serve as a tool in increasing income of the less educated and the unemployed by facilitating their transition to the labor market.
  • Article
    On the Moment-Determinacy of Power Lindley Distribution and Some Applications To Software Metrics
    (Acad Brasileira de Ciencias, 2021) Khalleefah, Mohammed; Ostrovska, Sofiya; Turan, Mehmet
    The Lindley distribution and its numerous generalizations are widely used in statistical and engineering practice. Recently, a power transformation of Lindley distribution, called the power Lindley distribution, has been introduced by M. E. Ghitany et at who initiated the investigation of its properties and possible applications. In this article, new results on the power Lindley distribution are presented. The focus of this work is on the moment-(in)determinacy of the distribution for various values of the parameters. Afterwards, certain applications are provided to describe data sets of software metrics.
  • Article
    Factors Influencing the Transition Time From Psoriasis to Psoriatic Arthritis: A Real-World Multicenter Analysis
    (Springer Heidelberg, 2025) Kilic, Gamze; Kilic, Erkan; Tekeoglu, Ibrahim; Sargin, Betul; Cengiz, Gizem; Balta, Nihan Cuzdan; Nas, Kemal
    To identify clinical and demographic predictors associated with the timing of transition from psoriasis (PsO) to psoriatic arthritis (PsA), and to compare the characteristics of patients with concurrent PsO-PsA onset versus those with prolonged transition. A multi-center, observational study was conducted using data from the Turkish League Against Rheumatism (TLAR) network including PsA patients fulfilling CASPAR criteria. Patients were categorized into two groups: Group 1 (concurrent PsO and PsA onset within +/- 1 year) and Group 2 (prolonged transition to PsA, > 1 year after PsO). Demographic, clinical, and laboratory characteristics, disease activity, and patient-reported outcomes were compared between groups. Logistic regression was employed to determine independent predictors of prolonged transition. Among 799 patients (mean age 46.8 +/- 12.3 years), 237 (29.7%) had concurrent onset and 562 (70.3%) had a prolonged transition, with a mean PsO-to-PsA interval of 12.9 +/- 9.6 years. Depression (p = 0.005) and fatigue levels (p = 0.011) were significantly higher in patients with prolonged transition to PsA. Multivariate analysis revealed that scalp psoriasis (OR = 7.162), nail psoriasis (OR = 3.270), family history of PsO (OR = 1.813), and enthesitis ever (OR = 2.187) were associated with prolonged transition. Conversely, family history of PsA (OR = 0.421) and older age at PsO onset (OR = 0.957) predicted shorter transition. Prolonged transition from PsO to PsA is influenced by distinct clinical and demographic factors. Scalp/nail psoriasis, family history of PsO, and enthesitis ever may signal higher risk for prolonged PsA onset. Recognizing these markers can support timely referral and intervention, minimizing diagnostic delay and improving long-term patient outcomes.
  • Review
    Citation - WoS: 3
    Citation - Scopus: 3
    Spatial Effectiveness in High-Rise Timber Towers: a Global Perspective
    (Mdpi, 2024) Ilgin, Huseyin Emre; Aslantamer, Ozlem Nur
    High-rise timber structures signify a rising trend, thanks to their significant environmental and economic advantages that occur over their complete lifespan. Enhancing spatial effectiveness in these structures is a critical design consideration for project feasibility. Currently, there has been no comprehensive study on the space efficiency of such towers. This article analyzed 79 cases all over the world to deepen the knowledge of design features shaping spatial efficiency. The critical findings are as follows: (1) the most common architectural preferences include residential function, a centrally located service core, and prismatic arrangements; (2) the preferred structural material is composite, while a shear walled frame system is the favored structural system; (3) the average spatial efficiency and percentage of core area to GFA were recorded at 84% and 10%, ranging from the lowest values of 70% and 4% to the highest values of 95% and 21%, respectively; and (4) no significant differences were detected in the effect of core design approaches on spatial effectiveness if appropriately planned, with similar inferences drawn concerning form and the structural material used. This article will assist in developing design directions for different interested parties, including architectural designers taking part in the advancement of high-rise timber towers.
  • Article
    Citation - WoS: 15
    Citation - Scopus: 15
    A Note on 'ψ-geraghty Type Contractions'
    (Springer international Publishing Ag, 2014) Karapinar, Erdal; Samet, Bessem
    Very recently, the notion of a psi-Geraghty type contraction was defined by Gordji et al. (Fixed Point Theory and Applications 2012: 74, 2012). In this short note, we realize that the main result via psi-Geraghty type contraction is equivalent to an existing related result in the literature. Consequently, all results inspired by the paper of Gordji et al. in (Fixed Point Theory and Applications 2012:74, 2012) can be derived in the same way.
  • Article
    Citation - WoS: 1
    Outperformance of CaO-Incorporated Alumina-Supported Pd Catalysts in Methanol Decomposition
    (Springer, 2025) Eryildirim, Busra; Oktar, Nuray; Dogu, Doruk
    This study aimed to investigate the impact of CaO incorporation to alumina-supported Pd catalysts on the methanol decomposition reaction. For this purpose, mayenite, alumina and/or calcium oxide-supported Pd catalysts were synthesized. The synthesized catalysts were characterized by XRD, FTIR, Laser Raman spectroscopy, N2 adsorption-desorption, pyridine adsorbed DRIFTS, CO2-TPD, XPS, SEM-EDS, and ICP-OES techniques. Catalytic activity tests were carried out over a 6 h reaction period in the range of 100-400 degrees C. The results of the characterization and activity tests showed that the addition of CaO had significant effects on the physicochemical properties of the catalyst as well as on the catalytic activity. By adding CaO to the alumina support material, the acidity was reduced, thus reducing the selectivity for dimethyl ether (DME) formation, which is significantly high for the 1Pd@Al2O3 catalyst, and increasing the H2 and CO selectivity. The mayenite-supported catalyst (1Pd@SGM), which contains alumina and calcium oxide in its unique crystal structure, showed an excellent catalytic performance close to complete methanol conversion with DME selectivity below 1% at 400 degrees C. In the stability test carried out at 350 degrees C for 6 h with 1Pd@Al2O3, 1Pd@SGM, and 1Pd@48CaO@Al2O3 catalysts used in the temperature scan, it was concluded that all catalysts were stable and 1Pd@SGM catalyst showed higher catalytic activity than the others.