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Review Citation - WoS: 88Citation - Scopus: 95Vision 2023: Forecasting Turkey's Natural Gas Demand Between 2013 and 2030(Pergamon-elsevier Science Ltd, 2013) Melikoglu, MehmetNatural gas is the primary source for electricity production in Turkey. However, Turkey does not have indigenous resources and imports more than 98.0% of the natural gas it consumes. In 2011, more than 20.0% of Turkey's annual trade deficit was due to imported natural gas, estimated at US$ 20.0 billion. Turkish government has very ambitious targets for the country's energy sector in the next decade according to the Vision 2023 agenda. Previously, we have estimated that Turkey's annual electricity demand would be 530,000 GWh at the year 2023. Considering current energy market dynamics it is almost evident that a substantial amount of this demand would be supplied from natural gas. However, meticulous analysis of the Vision 2023 goals clearly showed that the information about the natural gas sector is scarce. Most importantly there is no demand forecast for natural gas in the Vision 2023 agenda. Therefore, in this study the aim was to generate accurate forecasts for Turkey's natural gas demand between 2013 and 2030. For this purpose, two semi-empirical models based on econometrics, gross domestic product (GDP) at purchasing power parity (PPP) per capita, and demographics, population change, were developed. The logistic equation, which can be used for long term natural gas demand forecasting, and the linear equation, which can be used for medium term demand forecasting, fitted to the timeline series almost seamlessly. In addition, these two models provided reasonable fits according to the mean absolute percentage error, MAPE %, criteria. Turkey's natural gas demand at the year 2030 was calculated as 76.8 billion m(3) using the linear model and 83.8 billion m(3) based on the logistic model. Consequently, found to be in better agreement with the official Turkish petroleum pipeline corporation (BOTAS) forecast, 76.4 billion m(3), than results published in the literature. (C) 2013 Elsevier Ltd. All rights reserved.Review Citation - WoS: 35Citation - Scopus: 38Aptamer Hybrid Nanocomplexes as Targeting Components for Antibiotic/Gene Delivery Systems and Diagnostics: a Review(Dove Medical Press Ltd, 2020) Rabiee, Navid; Ahmadi, Sepideh; Arab, Zeynab; Bagherzadeh, Mojtaba; Safarkhani, Moein; Nasseri, Behzad; Tayebi, Lobat; Rabiee, Mohammad; Tahriri, MohammadrezaWith the passage of time and more advanced societies, there is a greater emergence and incidence of disease and necessity for improved treatments. In this respect, nowadays, aptamers, with their better efficiency at diagnosing and treating diseases than antibodies, are at the center of attention. Here, in this review, we first investigate aptamer function in various fields (such as the detection and remedy of pathogens, modification of nanoparticles, antibiotic delivery and gene delivery). Then, we present aptamer-conjugated nanocomplexes as the main and efficient factor in gene delivery. Finally, we focus on the targeted co-delivery of genes and drugs by nanocomplexes, as a new exciting approach for cancer treatment in the decades ahead to meet our growing societal needs.Review Citation - WoS: 90Citation - Scopus: 105Recommendations for Head and Neck Surgical Oncology Practice in a Setting of Acute Severe Resource Constraint During the Covid-19 Pandemic: an International Consensus(Elsevier Science inc, 2020) Mehanna, Hisham; Hardman, John C.; Shenson, Jared A.; Abou-Foul, Ahmad K.; Topf, Michael C.; AlFalasi, Mohammad; Holsinger, F. ChristopherThe speed and scale of the global COVID-19 pandemic has resulted in unprecedented pressures on health services worldwide, requiring new methods of service delivery during the health crisis. In the setting of severe resource constraint and high risk of infection to patients and clinicians, there is an urgent need to identify consensus statements on head and neck surgical oncology practice. We completed a modified Delphi consensus process of three rounds with 40 international experts in head and neck cancer surgical, radiation, and medical oncology, representing 35 international professional societies and national clinical trial groups. Endorsed by 39 societies and professional bodies, these consensus practice recommendations aim to decrease inconsistency of practice, reduce uncertainty in care, and provide reassurance for clinicians worldwide for head and neck surgical oncology in the context of the COVID-19 pandemic and in the setting of acute severe resource constraint and high risk of infection to patients and staff.Review Citation - WoS: 120Citation - Scopus: 142Dynamic Thermal and Hygrometric Simulation of Historical Buildings: Critical Factors and Possible Solutions(Pergamon-elsevier Science Ltd, 2020) Akkurt, G. G.; Aste, N.; Borderon, J.; Buda, A.; Calzolari, M.; Chung, D.; Turhan, C.Building dynamic simulation tools, traditionally used to study the hygrothermal performance of new buildings during the preliminary design steps, have been recently adopted also in historical buildings, as a tool to investigate possible strategies for their conservation and the suitability of energy retrofit scenarios, according to the boundary conditions. However, designers often face with the lack of reliable thermophysical input data for various envelope components as well as with some intrinsic limitations in the simulation models, especially to describe the geometric features and peculiarities of the heritage buildings. This paper attempts to bridge this knowledge gap, providing critical factors and possible solutions to support hygrothermal simulations of historical buildings. The information collected in the present work could be used by researchers, specialists and policy-makers involved in the conservation of building's heritage, who need to address a detailed study of the hygrothermal performance of historical buildings thorugh dynamic simulation tools.Review Citation - WoS: 18Citation - Scopus: 24A Literature Review on Mhe Selection Problem: Levels, Contexts, and Approaches(Taylor & Francis Ltd, 2015) Saputro, Thomy Eko; Masudin, Ilyas; Rouyendegh (Babek Erdebilli), Babak Daneshvar; Rouyendegh , Babak DaneshvarThis paper presents a review on selection problem of material handling equipment (MHE) and general equipment used in industry area. The issue on MHE is widely paid attention since MHE has contribution on material, good and product accomplishment. Few methods and softwares have been proposed and developed to select the most appropriate MHE for a complex selection problem. Today's high diverisity of MHE categories and types influence the generation of many possible choices which leads to the complexity. In this paper, a further discussion in terms of MHE and equipment including three major points namely level of selection, the context of selection problem and the approaches are served to highlight the complex MHE selection according to the number of possible choices provided, to analyse the consideration for the problem context, and to reveal the superior method for complex MHE selection. Forty-two papers collected from the past study are presented asscociating each point of the discussion.Review Citation - WoS: 10Citation - Scopus: 10Latest Developments in Engineered Skeletal Muscle Tissues for Drug Discovery and Development(Taylor & Francis Ltd, 2023) Ostrovidov, Serge; Ramalingam, Murugan; Bae, Hojae; Orive, Gorka; Fujie, Toshinori; Shi, Xuetao; Kaji, HirokazuIntroductionWith the advances in skeletal muscle tissue engineering, new platforms have arisen with important applications in biology studies, disease modeling, and drug testing. Current developments highlight the quest for engineering skeletal muscle tissues with higher complexity . These new human skeletal muscle tissue models will be powerful tools for drug discovery and development and disease modeling.Areas coveredThe authors review the latest advances in in vitro models of engineered skeletal muscle tissues used for testing drugs with a focus on the use of four main cell culture techniques: Cell cultures in well plates, in microfluidics, in organoids, and in bioprinted constructs. Additional information is provided on the satellite cell niche.Expert opinionIn recent years, more sophisticated in vitro models of skeletal muscle tissues have been fabricated. Important developments have been made in stem cell research and in the engineering of human skeletal muscle tissue. Some platforms have already started to be used for drug testing, notably those based on the parameters of hypertrophy/atrophy and the contractibility of myotubes. More developments are expected through the use of multicellular types and multi-materials as matrices . The validation and use of these models in drug testing should now increase.Review Citation - WoS: 247Citation - Scopus: 446Transformative Effects of Iot, Blockchain and Artificial Intelligence on Cloud Computing: Evolution, Vision, Trends and Open Challenges(Elsevier, 2019) Gill, Sukhpal Singh; Tuli, Shreshth; Xu, Minxian; Singh, Inderpreet; Singh, Karan Vijay; Lindsay, Dominic; Garraghan, PeterCloud computing plays a critical role in modern society and enables a range of applications from infrastructure to social media. Such system must cope with varying load and evolving usage reflecting societies' interaction and dependency on automated computing systems whilst satisfying Quality of Service (QoS) guarantees. Enabling these systems are a cohort of conceptual technologies, synthesized to meet demand of evolving computing applications. In order to understand current and future challenges of such system, there is a need to identify key technologies enabling future applications. In this study, we aim to explore how three emerging paradigms (Blockchain, IoT and Artificial Intelligence) will influence future cloud computing systems. Further, we identify several technologies driving these paradigms and invite international experts to discuss the current status and future directions of cloud computing. Finally, we proposed a conceptual model for cloud futurology to explore the influence of emerging paradigms and technologies on evolution of cloud computing. (C) 2019 Elsevier B.V. All rights reserved.Review Citation - WoS: 39Citation - Scopus: 43Hydropower in Turkey: Analysis in the View of Vision 2023(Pergamon-elsevier Science Ltd, 2013) Melikoglu, MehmetTurkey is a recently developed country, a regional power in the Middle East and an economic powerhouse of the region. Turkey's electricity demand is continuously increasing due to fast economic growth coupled with the country's vibrant young population. It is envisaged that this demand would keep on increasing almost exponentially in the next decade according to the recently avowed Vision 2023 agenda. According to which, the Turkish government ambitiously wants to provide 30.0% of the country's electricity demand from renewable energy sources by 2023. Turkey has vast renewable energy potential including hydro, geothermal, solar and wind. However, historically there is only one playmaker that is hydropower. Thus a detailed review of the current status and future prospects of Turkish hydropower market is urgently needed to generate a roadmap for the Vision 2023 agenda. This paper was intended to provide that vital information. Currently, more than 25.0% or 57.5 TWh of the country's electricity demand is supplied from hydropower. According to official projections this would increase to approximately 116.0 TWh in 2023. In this study, hydropower's supply rate of Turkey's annual electricity demand was assessed based on the official projections and a forecast was generated. Results showed that between 22.0% and 27.0% of Turkey's annual electricity demand should be supplied from hydropower in 2023. Therefore, between 22.5 TWh and 45.0 TWh of electricity should be generated from renewable energy sources other than hydropower to provide a total of 30.0% renewable energy based electricity generation in 2023. (C) 2013 Elsevier Ltd. All rights reserved.Review Citation - WoS: 75Citation - Scopus: 120Hybrid Blockchain Platforms for the Internet of Things (iot): a Systematic Literature Review(Mdpi, 2022) Alkhateeb, Ahmed; Catal, Cagatay; Kar, Gorkem; Mishra, AlokIn recent years, research into blockchain technology and the Internet of Things (IoT) has grown rapidly due to an increase in media coverage. Many different blockchain applications and platforms have been developed for different purposes, such as food safety monitoring, cryptocurrency exchange, and secure medical data sharing. However, blockchain platforms cannot store all the generated data. Therefore, they are supported with data warehouses, which in turn is called a hybrid blockchain platform. While several systems have been developed based on this idea, a current state-of-the-art systematic overview on the use of hybrid blockchain platforms is lacking. Therefore, a systematic literature review (SLR) study has been carried out by us to investigate the motivations for adopting them, the domains at which they were used, the adopted technologies that made this integration effective, and, finally, the challenges and possible solutions. This study shows that security, transparency, and efficiency are the top three motivations for adopting these platforms. The energy, agriculture, health, construction, manufacturing, and supply chain domains are the top domains. The most adopted technologies are cloud computing, fog computing, telecommunications, and edge computing. While there are several benefits of using hybrid blockchains, there are also several challenges reported in this study.Review Citation - WoS: 22Citation - Scopus: 36Principles of Reverse Electrodialysis and Development of Integrated-Based System for Power Generation and Water Treatment: a Review(Walter de Gruyter Gmbh, 2022) Othman, Nur Hidayati; Kabay, Nalan; Guler, EnverReverse electrodialysis (RED) is among the evolving membrane-based processes available for energy harvesting by mixing water with different salinities. The chemical potential difference causes the movement of cations and anions in opposite directions that can then be transformed into the electrical current at the electrodes by redox reactions. Although several works have shown the possibilities of achieving high power densities through the RED system, the transformation to the industrial-scale stacks remains a challenge particularly in understanding the correlation between ion-exchange membranes (IEMs) and the operating conditions. This work provides an overview of the RED system including its development and modifications of IEM utilized in the RED system. The effects of modified membranes particularly on the psychochemical properties of the membranes and the effects of numerous operating variables are discussed. The prospects of combining the RED system with other technologies such as reverse osmosis, electrodialysis, membrane distillation, heat engine, microbial fuel cell), and flow battery have been summarized based on open-loop and closed-loop configurations. This review attempts to explain the development and prospect of RED technology for salinity gradient power production and further elucidate the integrated RED system as a promising way to harvest energy while reducing the impact of liquid waste disposal on the environment.
