Efficacy of Gamma-Knife Radiosurgery in Grade 2 and Grade 3meningioma: a Single-Center, Long-Term Follow-Up Study

Abstract

Objectives: Gamma-Knife Radiosurgery (GKR) is a safe and effective treatment option in patients who have a high riskof complications in skull base and eloquent area-based tumors, in those to whom total surgery cannot be applied. Thepurpose was to analyze the results of radiosurgery in patients who underwent GKR for the residues or recurrent tumorsin high grade meningiomas. Methods: A retrospective screening was performed on patients who underwent GKR at Gazi University between 2004and 2018. The gender, mean age, location, volume, complications, size changes after GKR were noted. Results: A total of 35 (79.5%) patients were treated with Grade 2, and 9 (20.5%) were treated with Grade 3 meningio mas. The mean follow-up period was 48 months (3-108). The mean volume was noted as 9339 mm3 . The tumor controlrates after GKR were determined as 94% in Grade 2 and 55% in Grade 3 meningiomas. Conclusion: GKR can be applied as a safe and effective method for postoperative tumor control in high grade meningiomas.