Surface Plasmon Resonance Aptasensor for Soluble Icam-1 Protein in Blood Samples
| dc.authorid | Kavruk, Murat/0000-0001-5331-7253 | |
| dc.authorid | Dursun, Ali Dogan/0000-0001-9056-0025 | |
| dc.authorid | Tuna, Bilge Guvenc/0000-0003-1348-1336 | |
| dc.authorid | Yilmaz, Bayram/0000-0002-2674-6535 | |
| dc.authorid | Özalp, Veli Cengiz/0000-0002-7659-5990 | |
| dc.authorid | Yilmaz, Mahmut/0000-0001-5793-0805 | |
| dc.authorscopusid | 57196954194 | |
| dc.authorscopusid | 7102693052 | |
| dc.authorscopusid | 55279809300 | |
| dc.authorscopusid | 57574167900 | |
| dc.authorscopusid | 24921796800 | |
| dc.authorscopusid | 55738450300 | |
| dc.authorscopusid | 6504450287 | |
| dc.authorwosid | Kavruk, Murat/O-6694-2016 | |
| dc.authorwosid | Dursun, Ali Dogan/AAH-7617-2019 | |
| dc.authorwosid | Tuna, Bilge Guvenc/AAB-5827-2020 | |
| dc.authorwosid | Yilmaz, Bayram/IXD-3395-2023 | |
| dc.authorwosid | Özalp, Veli Cengiz/B-2940-2009 | |
| dc.authorwosid | Yilmaz, Mahmut/A-4984-2012 | |
| dc.contributor.author | Dursun, Ali Dogan | |
| dc.contributor.author | Dogan, Soner | |
| dc.contributor.author | Kavruk, Murat | |
| dc.contributor.author | Tasbasi, B. Busra | |
| dc.contributor.author | Sudagidan, Mert | |
| dc.contributor.author | Yilmaz, M. Deniz | |
| dc.contributor.author | Tuna, Bilge G. | |
| dc.contributor.other | Basic Sciences | |
| dc.contributor.other | Nutrition and Dietetics | |
| dc.date.accessioned | 2024-07-05T15:18:34Z | |
| dc.date.available | 2024-07-05T15:18:34Z | |
| dc.date.issued | 2022 | |
| dc.department | Atılım University | en_US |
| dc.department-temp | [Dursun, Ali Dogan] Atilim Univ, Sch Med, Dept Physiol, Ankara, Turkey; [Dursun, Ali Dogan] Atilim Univ, Vocat Sch Hlth Serv, Ankara, Turkey; [Dogan, Soner] Yeditepe Univ, Sch Med, Dept Med Biol, Istanbul, Turkey; [Kavruk, Murat] Atilim Univ, Sch Hlth Sci, Dept Nutr & Dietet, Ankara, Turkey; [Tasbasi, B. Busra; Sudagidan, Mert; Yilmaz, M. Deniz] Konya Food & Agr Univ, KIT ARGEM R&D Ctr, Konya, Turkey; [Yilmaz, M. Deniz] Konya Food & Agr Univ, Dept Bioengn, Konya, Turkey; [Yilmaz, Bayram] Yeditepe Univ, Sch Med, Dept Physiol, Istanbul, Turkey; [Ozalp, Veli C.] Atilim Univ, Sch Med, Dept Biol, Ankara, Turkey; [Tuna, Bilge G.] Yeditepe Univ, Sch Med, Dept Biophys, Istanbul, Turkey | en_US |
| dc.description | Kavruk, Murat/0000-0001-5331-7253; Dursun, Ali Dogan/0000-0001-9056-0025; Tuna, Bilge Guvenc/0000-0003-1348-1336; Yilmaz, Bayram/0000-0002-2674-6535; Özalp, Veli Cengiz/0000-0002-7659-5990; Yilmaz, Mahmut/0000-0001-5793-0805 | en_US |
| dc.description.abstract | Intercellular Adhesion Molecule-1 (ICAM-1) is considered to be a cancer biomarker in the assessment of metastatic potential in patients and an early indicator of atherosclerosis. A labelless biosensor based on the surface plasmon resonance (SPR) signal from the specific affinity interaction of an aptamer and a soluble ICAM-1 protein was developed for blood samples. The developed aptasensor provided real-time information on the concentration of the ICAM-1 protein in blood when integrated to a purification step based on a magnetic pull-down separation. The SPR aptasensor was highly specific with a limit of detection of 1.4/0.2 ng ml(-1), which was achieved through aptamer-functionalized silica-coated magnetic nanoparticles. | en_US |
| dc.description.sponsorship | Scientific and Technological Research Council of Turkey (TUBITAK) [115S233] | en_US |
| dc.description.sponsorship | This work was partly supported by a project grant number 115S233 from The Scientific and Technological Research Council of Turkey (TUBITAK). | en_US |
| dc.identifier.citationcount | 2 | |
| dc.identifier.doi | 10.1039/d1an02332b | |
| dc.identifier.endpage | 1668 | en_US |
| dc.identifier.issn | 0003-2654 | |
| dc.identifier.issn | 1364-5528 | |
| dc.identifier.issue | 8 | en_US |
| dc.identifier.pmid | 35312740 | |
| dc.identifier.scopus | 2-s2.0-85128126647 | |
| dc.identifier.startpage | 1663 | en_US |
| dc.identifier.uri | https://doi.org/10.1039/d1an02332b | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14411/1862 | |
| dc.identifier.volume | 147 | en_US |
| dc.identifier.wos | WOS:000771088000001 | |
| dc.identifier.wosquality | Q2 | |
| dc.institutionauthor | Dursun, Ali Doğan | |
| dc.institutionauthor | Kavruk, Murat | |
| dc.language.iso | en | en_US |
| dc.publisher | Royal Soc Chemistry | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.scopus.citedbyCount | 5 | |
| dc.subject | [No Keyword Available] | en_US |
| dc.title | Surface Plasmon Resonance Aptasensor for Soluble Icam-1 Protein in Blood Samples | en_US |
| dc.type | Article | en_US |
| dc.wos.citedbyCount | 5 | |
| dspace.entity.type | Publication | |
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