Sencar, Muhammed Erkam

Profile URL
https://hdl.handle.net/20.500.14411/7134
Name Variants
Sencar, M. E. M. E. Sencar S., Muhammed Erkam Sencar,M.E. M., Sencar Sancar, Muhammed Erkam Sencar, M. Erkam M.,Sencar S.,Muhammed Erkam Sencar, Erkam Sencar M. Muhammed Erkam, Sencar Sencar, Muhammed Erkam M.E.Sencar
Job Title
Doçent Doktor
Email Address
erkam.sencar@atilim.edu.tr
Main Affiliation
Internal Medical Sciences
Status
Website
ORCID ID
0000-0001-5581-4886
Scopus Author ID
57210468988
Turkish CoHE Profile ID
Google Scholar ID
WoS Researcher ID
AAN-8807-2021

Research Topics

Domains
Health Sciences
Fields
Medicine
Subfields
Endocrinology, Diabetes and MetabolismSurgeryPathology and Forensic Medicine
Specific Research Areas
Thyroid Cancer Diagnosis and Treatment
Thyroid Disorders and Treatments
Pituitary Gland Disorders and Treatments
Thyroid and Parathyroid Surgery
Vitamin D Research Studies

Sustainable Development Goals

SDG data is not available
Documents

51

Citations

386

h-index

12

Go to Scopus profile
Documents

65

Citations

441

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Publication Collaboration

Affiliation Name Count
Sağlık Bilimleri Üniversitesi 51
Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi 50
University of Health Sciences Antigua 22
Mardin Artuklu University 21
Ministry of Health 10
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Data obtained from OpenAlex
Scholarly Output

2

Articles

2

Views / Downloads

2/0

Supervised MSc Theses

0

Supervised PhD Theses

0

WoS Citation Count

0

Scopus Citation Count

0

Patents

0

Projects

0

WoS Citations per Publication

0.00

Scopus Citations per Publication

0.00

Open Access Source

1

Supervised Theses

0

JournalCount
European Archives of Oto-Rhino1
European Archives of Oto-Rhino-Laryngology1
Current Page: 1 / 1

Scopus Quartile Distribution

Competency Cloud

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Filters

2025 - 20262

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Author of Publication: search.filters.isAuthorOfPublication.00833f30-5eb1-4b1c-bd71-59e1e646118c

Scholarly Output Search Results

Now showing 1 - 2 of 2
  • Article
    Clinicopathological Predictors of Central Lymph Node Metastasis in Clinically Node-Negative Papillary Thyroid Carcinoma: A Retrospective Cohort Analysis
    (Springer, 2025-11-25) Sakiz, Davut; Calapkulu, Murat; Sencar, Muhammed Erkam; Unsal, Ilknur Ozturk; Kartal, Mehmet Zabit; Ucan, Bekir; Cakal, Erman
    PurposeThis retrospective cohort study aimed to identify clinicopathological predictors of central lymph node metastasis (CLNM) in patients with papillary thyroid carcinoma (PTC).MethodsA total of 503 patients with PTC who underwent thyroidectomy with central lymph node dissection were included. Preoperative clinical data, ultrasonographic features, and postoperative histopathological characteristics were analyzed.ResultsCLNM was detected in 209 (41.55%) patients. Male sex (odds ratio [OR] = 3.12, 95% CI: 1.82-5.35), irregular nodule borders (OR = 2.02, 95% CI: 1.25-3.26) and higher risk categories in the American Thyroid Association (ATA) ultrasonographic pattern stratification system (OR = 13.312, 95% CI: 8.623-20.551) were identified as independent preoperative predictors of CLNM. A simplified model incorporating only the ATA ultrasonographic pattern stratification system and male sex achieved 83.5% accuracy in predicting CLNM. Histopathological evaluation revealed lymphovascular invasion (OR = 4.61, 95% CI: 2.81-7.55), extrathyroidal extension (OR = 2.41, 95% CI: 1.52-3.83), and multifocality (OR = 1.58, 95% CI: 1.04-2.40) as independent predictors of CLNM, while lymphocytic thyroiditis (OR = 0.59, 95% CI: 0.39-0.89) was a protective factor.ConclusionThis study establishes that ATA ultrasonographic suspicion patterns combined with the male sex provide an accurate and simplified model for preoperative CLNM prediction in PTC, outperforming complex nomograms. Key independent predictors included male sex, irregular nodule margins, ATA high-risk patterns, lymphovascular invasion, extrathyroidal extension, and multifocality, while lymphocytic thyroiditis was protective. According to the current study, risk assessment and personalized management should favor a holistic approach, rather than focusing solely on individual risk factors.
  • Article
    Malignancy in Toxic Thyroid Adenoma: Revisiting Risk Assessment and Identifying Predictors
    (Springer, 2026-03-05) Calapkulu, Murat; Cayir, Derya; Sencar, Muhammed Erkam; Cakal, Erman; Sakiz, Davut; Unsal, Ilknur Ozturk; Tekinyildiz, Merve
    Background Toxic adenomas have traditionally been considered benign due to chronic TSH suppression, which is believed to inhibit thyroid tumorigenesis. However, emerging data challenge this dogma, reporting non-negligible malignancy rates even in toxic adenoma. This study aimed to assess thyroid cancer frequency and characteristics in surgically selected patients with toxic adenomas and to compare outcomes with propensity score-matched, surgically treated non-functioning nodules. Methods This retrospective, cross-sectional study included 204 surgically treated patients at a tertiary referral center, comprising 102 surgically selected toxic adenomas and 102 propensity score-matched, surgically treated non-functioning nodules. Clinical, biochemical, sonographic, scintigraphic, and histopathological data were analyzed. Multivariate logistic regression analysis was used to identify independent predictors of malignancy among toxic adenomas. Results In this surgically selected cohort, the malignancy rate was 16.7% for toxic adenomas and 40.2% for non-functioning nodules (p < 0.001). Papillary thyroid carcinoma comprised 82.4% of all cases, making it the leading histotype (82.4%). Among toxic nodules, higher fT4/fT3 ratio (cut-off:2.58, sensitivity:93.3%, specificity:54.2%) and European Thyroid Imaging and Reporting Data System categories 4-5 were independent predictors of malignancy. No significant differences were found between groups in terms of tumor size, invasion, American Thyroid Association risk stratification, or 5-year response rates. Conclusion Among surgically treated patients, the observed malignancy rate in toxic adenomas appears to be higher than traditionally expected. Elevated fT4/fT3 ratio and suspicious ultrasound features warrant closer evaluation. These findings support using ultrasound and biochemical markers in risk assessment of all thyroid nodules, regardless of functional status.