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Permanent URI for this collectionhttps://hdl.handle.net/20.500.14411/22
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Article The Role of Emotional Intelligence in the Relationship between Burnout and Perceived Quality of Care Among Oncology Nurses(Elsevier Sci Ltd, 2026) Sari, Tugba; Calis, Behice Belkis; Pars, Hatice; Guner, Perihan; Çalışkan, Behice BelkısPurpose: This study aimed to examine the relationships between burnout, emotional intelligence, and perceived caring behaviours among oncology nurses and to assess the predictive and mediating roles of these variables in explaining caring behaviours. Methods: A descriptive, cross-sectional study was conducted with 202 oncology nurses in T & uuml;rkiye. Data were collected using validated instruments measuring burnout, emotional intelligence, and caring behaviors. Data analysis employed descriptive statistics, Pearson correlation analyses, multiple linear regression, and structural equation modeling. Results: Emotional intelligence was positively associated with caring behaviours (r = .359, p < .001) and negatively associated with burnout subdimensions. Caring behaviours were inversely related to emotional exhaustion (r = -.258, p < .001), depersonalisation (r = -.397, p < .001), and reduced personal accomplishment (r = -.214, p = .002). In the regression model (R2 = .214, p < .001), emotional intelligence significantly predicted caring behaviours positively ((3 = .218, p = .002), while depersonalisation was a significant negative predictor ((3 = -.288, p < .001). However, emotional intelligence did not mediate the relationship between burnout and caring behaviours (Sobel test p = .332). Conclusion: While emotional intelligence was positively associated with caring behaviours and buffered the impact of burnout-particularly depersonalisation-it did not mediate the relationship between burnout and caring. These findings support the value of enhancing emotional intelligence to improve care quality and nurse well-being, though contextual factors may influence its mediating role.Article Evaluation of Clinical Characteristics, Risk Factors and Prognosis of Herpes Zoster (Shingles) Infection in Turkiye: Varicomp-Adult Study(Elsevier Sci Ltd, 2025) Ozgen-Top, Ozge; Karacaer, Zehra; Ozkan, Ece Firuze; Ozger, Hasan Selcuk; Saltoglu, Nese; Oztoprak-Cuvalci, Nefise; Senol, EsinObjective: The study aimed to determine the estimated prevalence of herpes zoster (HZ) infection in the adult population in Turkiye and the rates of HZ-associated complications and risk factors. Methods: This retrospective, multicenter ( n = 11), cross-sectional study was conducted between January 2016 and January 2022 and included all patients aged >= 18 years diagnosed with shingles following screening based on ICD-10 codes. The prevalence of HZ infection was calculated; rates of HZ-related complications (recurrence, hospitalization, postherpetic neuralgia [PHN]) and associated risk factors were determined. Results: A total of 6114 HZ patients were included; the estimated 5-year HZ prevalence in Turkiye was 908.7 per 10 0,0 0 0 population. Of the patients, 851 (14.2%) were immunocompromised, 366 (6%) were hospitalized due to HZ, 284 (8.9%) experienced PHN, 97 (3.2%) experienced recurrence of the patients. Risk factors for PHN were older age ( >= 50 years [OR = 3.19; P < 0.001)], and trigeminal dermatome involvement (OR = 2.45; P = 0.006). Antiviral use was associated with reduced PHN risk (OR = 0.16; P < 0.001). Conclusions: Our multicenter cross-sectional study revealed the high burden of HZ in Turkiye and high-lighted the potential for increasing prevalence due to risk factors including aging and comorbidities. (c) 2025 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)Article Knee Hyperextension in Chronic Stroke: Associated Biomechanical and Neuromuscular Factors(Elsevier Sci Ltd, 2025) Korkusuz, Sueleyman; Korkusuz, Busra Seckinogullari; Ozgoren, Nihat; Aritan, Serdar; Ceren, Ali Naim; Topcuoglu, Mehmet Akif; Balkan, Ayla FilBackground: This study aimed to determine the gait phase in which knee hyperextension occurs in stroke patients and to investigate the factors associated with knee hyperextension. Methods: This study included 30 stroke patients aged between 40 and 70 years with maximum knee hyperextension during the stance phase of gait. Muscle strength was evaluated with manual muscle test, and muscle tone was assessed with the Modified Ashworth Scale. Kinematic evaluation of the patients was made using the motion analysis system. Additionally, categorisation was made according to the stance phase of gait, where knee hyperextension was at its highest. Findings: A weak relationship was found between maximum knee hyperextension angle and gastrocnemius spasticity, a moderate relationship between knee flexor muscle strength, and a moderate relationship between ankle dorsiflexor muscle strength. In addition, a weak relationship was found between the maximum knee hyperextension and pelvic retraction angles. According to this clustering, it was observed that 66.67 % of the participants (20 people) showed maximum knee hyperextension in the single support phase. It was observed that the participants who had maximum knee hyperextension, especially after the mid-stance phase, had higher mean gastrocnemius spasticity. It was also observed that participants in Cluster 4, with a greater amount of maximum knee hyperextension, had the worst clinical parameters. Interpretation: Our study observed that the degree of maximum knee hyperextension was related to knee flexor and ankle dorsiflexor muscle strengths, gastrocnemius spasticity and pelvic retraction. As clinical parameters worsened, maximum knee hyperextension was thought to occur late in the stance phase. Clinical Trial code: NCT05679700Article Citation - WoS: 3Citation - Scopus: 3Turkish Nurses' Knowledge, Attitudes and Practices in the Management of Incontinence Associated Dermatitis: a Descriptive and Cross-Sectional Study(Elsevier Sci Ltd, 2025) Sonmez, Munevver; Kisacik, Oznur Gurlek; Korkmaz, Serap; Gürlek Kısacık, ÖznurObjective: This study aimed to determine nurses' current knowledge, attitudes, and practices in adult intensive care units and palliative care clinics regarding incontinence-associated dermatitis (IAD). Materials and methods: This descriptive cross-sectional study was conducted with 355 nurses in adult intensive care and palliative services at two hospitals. Data were collected between 5.03.2022 and 15.06.2022 using the" Nurse Demographic Form" and the "Knowledge, Attitude and Practice of Nurses in Managing Incontinence- Associated Dermatitis Questionnaire". Results: The nurses' mean scores for "Knowledge of IAD Etiology and Diagnosis" were 19.11 (SD 3.29), mean scores for "Knowledge of IAD Risk Factors" were 23.82 (SD 4.27), mean scores for "Attitude Toward IAD Prevention" were 10.1 (SD 2.49), and mean scores for "Practices for IAD Prevention" were 23.71 (SD 3.97). It was found that nurses who used a risk assessment tool to diagnose IAD (p = 0.001), had a procedure or protocol (p = 0.001), and received training on IAD (p < 0.001) had significantly higher "Attitude Towards Prevention of IAD" scores. There was a positive correlation between the number of patients with IAD cared for by the nurses participating in the study and the scores of "Practices to Prevent IAD"and "Knowledge of IAD Risk Factors", "Knowledge of IAD Etiology and Diagnosis"and "Attitude Towards Preventing IAD"(p < 0.001). Conclusion: This study found that intensive care and palliative care nurses' knowledge, attitudes, and practices regarding IAD were insufficient. Considering that IAD is encountered more frequently in these units, it is essential to provide continuous and practical training to nurses about IAD, use risk assessment tools to prevent and treat IAD, determine protocols, establish clinical guidelines, and implement and standardize them.Article Citation - WoS: 3Citation - Scopus: 4Comparison of the Escape Room and Storytelling Methods in Learning the Stress Response: a Randomized Controlled Pilot Study(Elsevier Sci Ltd, 2025) Dogu, Nilgun; Boztepe, Handan; Topal, Cansu Akdag; Sonmez, Munevver; Yuceer, Bugse; Bayraktar, NurhanAim: The purpose of this study was to evaluate the effect of the Escape Room and Storytelling methods on nursing students' learning about the topic of stress response. Background: It is recommended that new generations be trained using innovative teaching methods that differ from traditional teaching methods. The Escape Room and Storytelling methods are among the techniques that have been used and recommended for this purpose. Design: The study was conducted with a randomized, controlled design. Methods: Thirty-five (n = 35) second-year undergraduate nursing students were randomly divided into two groups, one group was trained on stress response using the Escape Room method, while the other group was trained using the Storytelling method. Focus-group interviews were conducted with the students after the interventions. Results: There was a significant difference between the groups in terms of the median post-intervention knowledge assessment score. It was determined that the students in the Escape Room group scored significantly higher than those in the Storytelling group (p < 0.05) Conclusions: The use of these methods, which ensure the active participation of students and increase their motivation, effectively contributes to meeting the educational needs of students and increases their level of satisfaction.Article Citation - WoS: 1Citation - Scopus: 1Knowledge Levels and Attitudes of Turkish Nursing Students Regarding Medical Device-Related Pressure Injuries and Factors Influencing Them: a Cross-Sectional Study(Elsevier Sci Ltd, 2025) Erzincanli, Saadet; Kisacik, Oznur Gurlek; Sonmez, Munevver; Gürlek Kısacık, ÖznurAim: The aim of this study was to determine nursing students' levels of knowledge and attitudes regarding medical device-related pressure injuries (MDRPIs), as well as the factors influencing these. Materials and methods: This descriptive and cross-sectional study was conducted with 581 nursing students between January and May 2024. Data were collected using the Student Information Form, the Medical Device Related Pressure Injury Knowledge Assessment Test (MDRPI-KAT), and the Medical Device Related Pressure Injury Attitude Questionnaire (MDRPI-AQ). Results: The nursing students had a mean score of 8.76 +/- 2.68 on the MDRPI-KAT, indicating an overall correct answer percentage of 54.7%. The mean total score on the MDRPI-AQ was 44.08 +/- 8.12. Furthermore, 75.0% of the nursing students (n = 436) achieved a positive attitude score (>40 points). According to the results of the structural equation model, the scores on the MDRPI-KAT among nursing students had a statistically significant effect on their scores on the MDRPI-AQ (beta = 0.585, p = 0.002). Conclusion: This study found that the nursing students exhibited insufficient knowledge about MDRPIs.Despite this, the nursing students demonstrated a positive attitude toward MDRPIs.Article Citation - Scopus: 1Development and Psychometric Evaluation of the Treatment Management Adherence Scale for Children With Multiple Sclerosis(Elsevier Sci Ltd, 2024) Yuksel, Didem; Yardimci, FigenBackground: Pediatric multiple sclerosis (pMS) is a chronic inflammatory, demyelinating, and neurodegenerative disease affecting the central nervous system in children and adolescents The aim of this correlational, comparative study was to develop an assessment scale for adherence to treatment management in pMS. Methods: Two measurement tools were used to develop a scientifically sound tool to assess adherence in pediatric patients (12-18 years) diagnosed with multiple sclerosis (MS). Cases of pMS (n = 120) in 7 hospitals in Turkey were included between August 2021-February 2022. The tools were a "Sociodemographic and Disease-Related Information" and a newly developed "Treatment Management Adherence Scale for Children with Multiple Sclerosis". The form and questionnaire were completed by the children through online using the Zoom platform in approximately 10 min. The questionnaire on adherence contains 16 items related to the disease and treatment, scored in a 5-point Likert type. Face validity was established by pretesting with 20 children, and construct validity was established using the statistical methods of exploratory factor analysis and confirmatory factor analysis. For the reliability of the scale, Cronbach's Alpha and omega coefficients, item test correlation values, split-half, test-retest techniques were used. Results: There were 120 eligible patients, 71.2 % girls, with mean age (fSD) 13,6 f 2,2 years at disease onset and 15,7 f 1,5 at the time of the study, all under disease-modifying therapy. The sample size and items were sufficient to conduct a factor analysis. The Cronbach's Alpha and Omega value was 0.75, indicating participants' opinions were consistent across items. The mean content validity index was 0.93, showing the scale represented the measured data, and the exploratory factor analysis showed the scale measures adherence in 55 % of patients (desired figures: >0.80 and 40-60 % respectively). The 16 items of the questionnaire were grouped into 4 dimensions. These dimensions were termed 'physiological', 'self-concept', 'role function' and 'interdependence', in line with different styles of adaptation. The total score can be between 16 and 80, with higher scores indicating strong adherence to treatment. The mean total score of 54,3 f 9,53 (min=31, max= 75) in this study was in the "moderate adherence" range. Conclusions: This new scale is the first to assess adherence in pMS. The study supports its validity, reliability, and likelihood to address adjustment issues in children and adolescents with MS accurately and can be recommended for clinical use.Article Citation - WoS: 3Citation - Scopus: 3Incidence of Medical Device-Related Pressure Injuries and Identification of Risk Factors in the Neonatal Unit(Elsevier Sci Ltd, 2024) Yarkiner, Zalihe; Bahar, Arzu; Sonmez, Munevver; Kapan, Emine; Sahin, Simge; Kostekci, Ezgi; Erdeve, OmerAim: This study was conducted to investigate the incidence of medical device-related pressure injuries (MDRPIs) and the risk factors influencing their occurrence in the neonatal intensive care unit (NICU). Method: This study is a prospective, descriptive study. The research was conducted with 116 newborns between June 1, 2022, and June 1, 2023. Newborns who stayed in the neonatal intensive care unit for at least 24 h were observed daily for medical device-related pressure injuries under and around each medical device throughout their stay in the intensive care unit. The "Case Report Form," "MDRPIs Monitoring Form," "Braden Q scale for children," National Pressure Injury Advisory Panel (NPIAP) Pressure Grading, and Glasgow Coma Scale were used in the research. Results: The incidence of medical device-related pressure injuries is 35.3 % (41/116). It was found that 38.1 % (16/42) of medical device-related pressure injuries developed due to Near-Infrared Spectroscopy (NIRS) probes, and 33.5 % (14/42) developed due to medical devices related to the respiratory system. In terms of anatomical location, 38.1 % occurred on the forehead, and 23.8 % on the arm/leg. The difference between birth weight, gestational age, development of MDRPIs in newborns receiving sedation and inotropes was found to be statistically significant. Regression analysis identified gestational age (p = 0.040, OR = 0.795, 95%CI = [0.632-1.000]) as an independent risk factor for the occurrence of medical device-related pressure injuries. Conclusions: The incidence of medical device-related pressure injuries in newborns was relatively high in this study, with gestational age being the most significant risk factor for MDRPIs formation. It is crucial for neonatal intensive care nurses to consider associated risk factors while providing newborn care and implement appropriate preventive measures to reduce the incidence of MDRPIs.Article Citation - WoS: 1Citation - Scopus: 1Identifying Risk Factors for Blood Culture Negative Infective Endocarditis: an International Id-Iri Study(Elsevier Sci Ltd, 2024) Filiz, Mine; Erdem, Hakan; Ankarali, Handan; Puca, Edmond; Ruch, Yvon; Santos, Lurdes; Agalar, CananBackground: Blood culture-negative endocarditis (BCNE) is a diagnostic challenge, therefore our objective was to pinpoint high-risk cohorts for BCNE. Methods: The study included adult patients with definite endocarditis. Data were collected via the Infectious Diseases International Research Initiative (ID-IRI). The study analysing one of the largest case series ever reported was conducted across 41 centers in 13 countries. We analysed the database to determine the predictors of BCNE using univariate and logistic regression analyses. Results: Blood cultures were negative in 101 (11.65 %) of 867 patients. We disclosed that as patients age, the likelihood of a negative blood culture significantly decreases (OR 0.975, 95 % CI 0.963-0.987, p < 0.001). Additionally, factors such as rheumatic heart disease (OR 2.036, 95 % CI 0.970-4.276, p = 0.049), aortic stenosis (OR 3.066, 95 % CI 1.564-6.010, p = 0.001), mitral regurgitation (OR 1.693, 95 % CI 1.012-2.833, p = 0.045), and prosthetic valves (OR 2.539, 95 % CI 1.599-4.031, p < 0.001) are associated with higher likelihoods of negative blood cultures. Our model can predict whether a patient falls into the culture-negative or culture-positive groups with a threshold of 0.104 (AUC +/- SE = 0.707 +/- 0.027). The final model demonstrates a sensitivity of 70.3 % and a specificity of 57.0 %. Conclusion: Caution should be exercised when diagnosing endocarditis in patients with concurrent cardiac disorders, particularly in younger cases.Review Citation - WoS: 194Citation - Scopus: 215Stimulus-Responsive Sequential Release Systems for Drug and Gene Delivery(Elsevier Sci Ltd, 2020) Ahmadi, Sepideh; Rabiee, Navid; Bagherzadeh, Mojtaba; Elmi, Faranak; Fatahi, Yousef; Farjadian, Fatemeh; Hamblin, Michael R.In recent years, a range of studies have been conducted with the aim to design and characterize delivery systems that are able to release multiple therapeutic agents in controlled and programmed temporal sequences, or with spatial resolution inside the body. This sequential release occurs in response to different stimuli, including changes in pH, redox potential, enzyme activity, temperature gradients, light irradiation, and by applying external magnetic and electrical fields. Sequential release (SR)-based delivery systems, are often based on a range of different micro- or nanocarriers and may offer a silver bullet in the battle against various diseases, such as cancer. Their distinctive characteristic is the ability to release one or more drugs (or release drugs along with genes) in a controlled sequence at different times or at different sites. This approach can lengthen gene expression periods, reduce the side effects of drugs, enhance the efficacy of drugs, and induce an anti-proliferative effect on cancer cells due to the synergistic effects of genes and drugs. The key objective of this review is to summarize recent progress in SR-based drug/gene delivery systems for cancer and other diseases. (C) 2020 Elsevier Ltd. All rights reserved.
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