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Permanent URI for this collectionhttps://hdl.handle.net/20.500.14411/22
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Article Barriers to Adherence After A Self-Management Lymphedema Education Program Among Women with Breast Cancer-Related Lymphedema(Lippincott Williams and Wilkins, 2026) Uçar, G.C.; Kapucu, S.; Arıkan Dönmez, A.A.; Ozdemir, O.; Dönmez, Ayşe A.Objectives: – Lymphedema associated with breast cancer is a chronic condition that negatively affects women’s physical functioning, psychosocial well-being, and quality of life. Although self-management education is a fundamental component of lymphedema care, many women struggle to maintain recommended practices in daily life over time. To explore how women with breast cancer-related lymphedema integrate self-management education into daily life over time and to identify barriers to sustained adherence 1 year or more after completing a self-management lymphedema education program (SMLEP). Methods: – A descriptive phenomenological qualitative design was used. In-depth, semistructured interviews were conducted with 17 women diagnosed with breast cancer-related lymphedema. Data were analyzed using qualitative content analysis. Results: – Two overarching themes were identified: problems caused by lymphedema and barriers to self-management. Problems included limitations in activities of daily living, pain, restricted social participation, and body image disturbance. Barriers included economic difficulties, decreased belief in treatment effectiveness, boredom and forgetfulness, lack of family support, absence of monitoring mechanisms, use of the dominant arm, and symptom regression. Conclusions: – Women with breast cancer-related lymphedema face interconnected physical, emotional, and contextual challenges that limit long-term self-management adherence beyond knowledge deficits alone. © 2026Book Part A Niche-Based Perspective to Stem and Cancer Stem Cells of the Lung(Springer, 2025) Boyacıoğlu, Özge; Kalali, Berfin Deniz; Tongün, Ege; Korkusuz, PetekLungs carry the principle function for the conduction and exchange of air through the primary, secondary, tertiary bronchi, bronchioles, and alveoli, resulting in the exchange of oxygen to carbon dioxide within the human tissues. Lung stem and progenitor cells enable differentiation of parenchymal and stromal elements and provide homeostasis and regeneration in the microenvironment against pulmonary diseases. Tumor-initiating cancer cells (TICs) refer to a subpopulation named as cancer stem cells (CSCs) of lung cancer exhibiting high self-renewal and proliferation capacity by Notch, Hippo, Hedgehog, and Wnt signaling pathways that leads to tumor development or recurrence. Lung cancer stem cells (LCSCs) are characterized by distinct genotypic or phenotypic alterations compared to healthy lung stem cells (LSCs) that provide a potential target to treat lung cancer. Therefore, understanding the cascades responsible for the transformation of healthy to CSCs is essential to develop new targeted therapy approaches. In this chapter, we precisely highlight the latest researches on LSCs and CSCs, key signaling mechanisms within the perspective of novel targeted therapy strategies. © 2025 Elsevier B.V., All rights reserved.Article Citation - WoS: 1An Updated Meta-Analysis on the Association Between Celiac Disease and Cardiovascular Diseases(E-Century Publishing Corp, 2025) Faraji, Mahdi; Khademi, Reza; Maleki, Maede; Jafari, Fatemeh; Olama, Ensiyeh; Saghafi, Mohammad Sadra; Anar, Mahsa AsadiObjectives: Research on the relationship between celiac disease (CD) and cardiovascular disease (CVD) is still ongoing, and different studies have reported contradictory findings. To carry out a meta-analysis and systematic review to look into the connection between CD and CVD risk. Methods: A thorough search was conducted in PubMed, Scopus, and Google Scholar databases up to February 19, 2024. Relevant articles were extracted, and the titles, abstracts, and full texts of the related articles were screened. The quality of the studies was assessed using the Joanna Briggs Institute critical appraisal tools. Results: Nine cohort and one case-control studies involving 49,621,333 individuals were included in the meta-analysis. The pooled analysis revealed a 7% increased risk of CVD in CD patients compared to controls (OR: 1.07, 95% CI: 1.03-1.10, P < 0.05). Significant heterogeneity was observed among studies (I2 = 76%, P < 0.001). Conclusion: This meta-analysis provides evidence of a modest but significant increase in CVD risk in patients with CD. The results highlight the importance of considering cardiovascular health in CD treatment and the need for further research to elucidate the mechanisms underlying this association and to develop targeted prevention strategies.Article Effect of Training Based on Travelbee's Human-To Relationship Model on Prenatal Attachment, Fear of Childbirth, and Anxiety in Pregnant Women With Fear of Childbirth a Randomized Controlled Trial(Slack Inc, 2025) Sari, T.; Gürhan, N.; Guerhan, NerminPURPOSE: To investigate the effects of education provided to pregnant women with fear of childbirth according to Travelbee's Human-to-Human Relationship Model on fear of birth, prenatal attachment, and anxiety. METHOD: This prospective, randomized controlled study was conducted between June and August 2023. Participants included 62 pregnant women divided into intervention and control groups. Pregnant primiparous women who had fear of childbirth were selected for the intervention group, receiving an eight-session educational program based on Travelbee's model. RESULTS: At the end of the educational program, decreased fear of childbirth, lower anxiety, and higher prenatal attachment were detected in the intervention group. Results showed a statistically significant difference in the intervention group compared to the control group. CONCLUSION: Birth preparation education prepared according to Travelbee's model is an effective method for reducing pregnant women's fear of childbirth and anxiety and increasing prenatal attachment level.Erratum Erratum: Correction: Cardiac Hypertrophy Caused by Hyperthyroidism in Rats: the Role of ATF-6 and Trpc1channels (Canadian Journal of Physiology and Pharmacology (2021) 99 11 Doi: 10.1139/Cjpp-2021-0260)(Canadian Science Publishing, 2024) Bektur, N.E.; Şahin, E.; Kacar, S.; Bağcı, R.; Karakaya, Ş.; Burukoglu-Donmez, D.; Şahintürk, V.; Aykanat, Nuriye Ezgi Bektur; Donmez, Dilek Burukoglu; Burukoğlu Dönmez, Dilek; Bektur Aykanat, Nuriye Ezgi