Browsing by Author "Tulek, N."

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Investigation of Tetanus Seropositivity Levels in Adult Patients with Rabies Risk Exposure Admitted To a Hospital in Ankara
(Journal of Infection in Developing Countries, 2025) Gürkaynak, P.; Demircan, Ş.A.; Tulek, N.; Kinikli, S.; Erdi̇Nç, F.Ş.; Tuncer, G.; 01. Atılım University
Introduction: This study aimed to assess tetanus seropositivity levels among adult patients admitted to a tertiary care hospital following rabies risk exposure, and to explore potential factors influencing their immunological status. Methodology: This cross-sectional descriptive epidemiological study included 182 adult individuals (68 females and 114 males) who presented to the hospital following rabies risk exposure. The demographic data was collected during a face-to-face interview, and the tetanus antibody concentrations were assessed using a micro-enzyme-linked immunosorbent assay (ELISA) kit. Serum antibody levels of ≥ 0.1 IU/mL were defined as “seropositive”, while values below this threshold were considered “seronegative”. Results: Seropositivity was identified in 81.9% of the patients. There was a significant decline in antibody levels with age (p < 0.001). The Spearman correlation analysis showed a moderately significant negative correlation between age and antibody titers (r = – 0.404, p < 0.001). In addition, there were significantly higher tetanus antibody levels in patients from urban areas, those vaccinated during pregnancy, and those vaccinated within the past 10 years (p = 0.025, 0.036, and 0.013, respectively). Conclusions: Overall, the results highlight a reduction in tetanus antibody levels with age, emphasizing the importance of receiving a booster dose every 10 years. In addition, rabies risk exposure, particularly in older adults, presents a valuable opportunity to administer tetanus vaccination. © 2025 Gürkaynak et al.
Citation - WoS: 41
Citation - Scopus: 40
Profiling Infectious Diseases in Turkey After the Influx of 3.5 Million Syrian Refugees
(Elsevier Sci Ltd, 2020) Ergonul, O.; Tulek, N.; Kayi, I; Irmak, H.; Erdem, O.; Dara, M.; 01. Atılım University
Background: Since 2011, the conflict in Syria has led to over five million refugees. Turkey hosts the highest number of Syrian refugees in the world. By February 2019 over 3.6 million people had fled to Turkey to seek safety. Only 6.1% of Syrian refugees live in temporary shelters. Owing to the disrupted healthcare services, many children coming from the conflict zones are less likely to have received vaccination. In temporary shelters immunization coverage is >95% and the refugee population is receptive to vaccination. Aims: The objective of this study was to review the infectious diseases situation among Syrian refugees in Turkey. Sources: We have reviewed the reports and studies provided by the governmental and non-governmental organizations and obtained more detailed data from the Ministry of Health in Turkey. Content: Between 2012 and 2016, 1 299 209 cases of respiratory tract infection and 158 058 episodes of diarrhoea with 59 bloody diarrhoeas were reported; 1354 hepatitis A cases and 108 active tuberculosis cases were detected and treated in the temporary shelters for Syrian refugees. Overall in Turkey, 7794 cutaneous leishmaniasis have been reported. Implications: Since the influx of Syrian refugees, there has been an increase in cases of leishmaniasis and measles. No significant increase was detected for tuberculosis, other vector-borne infections, and healthcare associated or sexually transmitted infections. The Syrian refugees can be considered as a vulnerable group in Turkey due to their living and working conditions. Based on available data and our detailed analysis, the numbers show a stable situation regarding infectious diseases. (C) 2019 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
Seroprevalence of Vaccine Preventable Viral Diseases and Vaccine Response Among Hiv Positive Patients
(Wiley, 2019) Erdinc, F. S.; Dogan, K.; Tulek, N.; Ertem, G. Tuncer; Kinikli, S.; 01. Atılım University
[No Abstract Available]