Browsing by Author "Manolache, S."
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Conference Object Citation - WoS: 1Effects of Functional Groups, Biosignal Molecules and Nanotopography on Cellular Proliferation(Springer, 2009) Sasmazel, H. T.; Manolache, S.; Guemuesderelioglu, M.; Metallurgical and Materials Engineering; 06. School Of Engineering; 01. Atılım UniversityThe aim Of this Study is the development of novel cell Support materials for fibroblast cell cultivation by using low-pressure plasma assisted treatment. Poly(epsilon-caprolactone) (PCL) membranes were prepared by solvent-casting technique. The plasma assisted treatment was focused oil generating a nano-topography and obtaining COOH functionalities oil the Surface of the membranes. The immobilization of biomolecules onto the PCL membranes was realized after the plasma treatment, The membranes prepared were characterized by various methods before and after the biomodification. L929 mouse fibroblasts were used for cell Culture evaluation. The prominent roles Of Surface nano-topography and carboxylic groups generated by the plasma in obtaining better cell growth on PCL Surfaces are highlighted in this study.Conference Object Impact of Nanotopography And/Or Functional Groups on Periodontal Ligament Cell Growth(Springer, 2010) Sasmazel, Hilal Turkoglu; Manolache, S.; GumusderlIoglu, M.; Metallurgical and Materials Engineering; 06. School Of Engineering; 01. Atılım UniversityThe main purpose of this contribution was to obtain COOH functionalities and/or nanotopographic changes on the surface of 3D, non-woven polyester fabric (NWPF) discs (12.5 mm in diameter) by using low pressure water/O-2 plasma assisted treatments. The prepared discs were characterized by various methods after the plasma treatment. Periodontal ligament (PDL) fibroblasts were used in cell culture studies. The cell culture results showed that plasma treated 3D NWPF discs are favorable for PDL cell spreading, growth and viability due to the presence of functional groups and/or the nanotopography of their surfaces.Conference Object Insulin and Heparin Bioactivation of 3d Nwpf Discs by Water/O2 Plasma for I929 Fibroblast Cell Cultivation(Wiley-blackwell, 2010) Sasmazel, H. Tuerkodlu; Manolache, S.; Gumupdereliodlu, M.; Metallurgical and Materials Engineering; 06. School Of Engineering; 01. Atılım University[No Abstract Available]
