Browsing by Author "Kinikli, S."
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Article Investigation of Tetanus Seropositivity Levels in Adult Patients with Rabies Risk Exposure Admitted To a Hospital in Ankara(Journal of Infection in Developing Countries, 2025) Gürkaynak, P.; Demircan, Ş.A.; Tulek, N.; Kinikli, S.; Erdi̇Nç, F.Ş.; Tuncer, G.; 01. Atılım UniversityIntroduction: This study aimed to assess tetanus seropositivity levels among adult patients admitted to a tertiary care hospital following rabies risk exposure, and to explore potential factors influencing their immunological status. Methodology: This cross-sectional descriptive epidemiological study included 182 adult individuals (68 females and 114 males) who presented to the hospital following rabies risk exposure. The demographic data was collected during a face-to-face interview, and the tetanus antibody concentrations were assessed using a micro-enzyme-linked immunosorbent assay (ELISA) kit. Serum antibody levels of ≥ 0.1 IU/mL were defined as “seropositive”, while values below this threshold were considered “seronegative”. Results: Seropositivity was identified in 81.9% of the patients. There was a significant decline in antibody levels with age (p < 0.001). The Spearman correlation analysis showed a moderately significant negative correlation between age and antibody titers (r = – 0.404, p < 0.001). In addition, there were significantly higher tetanus antibody levels in patients from urban areas, those vaccinated during pregnancy, and those vaccinated within the past 10 years (p = 0.025, 0.036, and 0.013, respectively). Conclusions: Overall, the results highlight a reduction in tetanus antibody levels with age, emphasizing the importance of receiving a booster dose every 10 years. In addition, rabies risk exposure, particularly in older adults, presents a valuable opportunity to administer tetanus vaccination. © 2025 Gürkaynak et al.Conference Object Seroprevalence of Vaccine Preventable Viral Diseases and Vaccine Response Among Hiv Positive Patients(Wiley, 2019) Erdinc, F. S.; Dogan, K.; Tulek, N.; Ertem, G. Tuncer; Kinikli, S.; 01. Atılım University[No Abstract Available]
