Browsing by Author "Bolat, Mustafa Suat"

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Can Cardiometabolic Index Predict Erectile and Other Sexual Functions in Men With Metabolic Syndrome
(MRE Press, 2025) Bolat, Mustafa Suat; Dundar, Cihad; Asci, Ramazan
Background: We aimed to examine the impact of the cardiometabolic index (CMI) on various aspects of male sexuality across different age groups, with a focus on the presence of metabolic syndrome (MetS). Methods: We included a total of 454 sexually active men, 127 with MetS and 327 without MetS. We assessed sexual function using the long form of the International Index of Erectile Function (IIEF) questionnaire. According to the IIEF guestionnaire, a total score <26 is defined as erectile dysfunction (ED). We calculated the CMI using the formula: (Triglyceride/High Density Lipoprotein-cholesterol) x (Waist circumference/Height). The relationship between sexual function scores and CMI was analyzed in men, using a 50-year age cutoff. We investigated the predictive power of the CMI for ED. Results: The mean CMI was higher in men with MetS than those without (p-value < 0.001). The MetS group had lower mean testosterone levels and erectile function scores than the non-MetS group (p-value < 0.05). Men under 50 with MetS had lower sexual function scores for erectile function, sexual satisfaction, orgasm, desire and overall satisfaction than their non-MetS counterparts (p-value < 0.05). Regardless of MetS grouping, at a CMI cut-off value of 0.50, sensitivity and specificity were 77% and 55%, respectively (p-value < 0.001). However, MetS group had low sensitivity and specificity at a CMI cut-off value of 1.46 (56% and 57%, respectively; p-value > 0.05). Logistic regression revealed that both CMI and age were significant risk factors for sexual dysfunction (Odds Ratio = 2.672 and 1.081, respectively; p-value = 0.001). Conclusions: The CMI predicted sexual dysfunction, including ED, in younger men. The presence of MetS increased the risk of sexual dysfunction. However, CMI did not predict male sexual dysfunction in older men, independent of MetS. Our findings suggest that CMI can be a predictor of various aspects of sexual functions, particularly in younger men.
Citation - WoS: 1
Citation - Scopus: 2
Which Is Better To Predict Erectile Dysfunction and Male Sexual Function in the Context of Metabolic Syndrome: Triglyceride-Glucose Index or Visceral Adiposity Index?: a Retrospective Cross-Sectional Study
(Springer, 2024) Bolat, Mustafa Suat; Bolat, Ipek Akalin; Dundar, Cihad; Asci, Ramazan
PurposeMany factors influence male sexual function, including metabolic disorders such as metabolic syndrome (MetS). We aimed to investigate the effects of two metabolic indices, the triglyceride-glucose (TyG) index and the visceral adiposity index (VAI), on male sexual function.MethodsA total of 400 men having sexual dysfunction were included. Anthropological data, comorbidities were recorded. Serum total testosterone, prolactin, and estradiol levels were recorded. Sex-specific VAI was calculated using the [(WC/39.68) + (1.88xMI)] x (TG/1.03) x (1.31/HDL) formula and using Ln (fasting triglycerides) x (fasting glucose)/2] formula, TyG index was calculated. Turkish-validated 15-item long-form of the International Index of Erectile Dysfunction (IIEF) questionnaire and male sexual health questionnaire (MSHQ) were used for erectile function and ejaculatory function, respectively. The ROC analysis was used to evaluate the predictive abilities of TyG and VAI cut-off values for ED risk.ResultsA higher TyG index and VAI were associated with an increased risk of ED. The presence of MetS further worsened sexual function, with lower scores in sexual satisfaction, orgasm, desire, and general satisfaction. The TyG index and VAI showed similar predictive abilities for ED. Patients with MetS had worse ejaculation quality compared to those without MetS.ConclusionsThese findings highlight the potential of the TyG index and VAI as convenient tools for predicting and assessing sexual dysfunction in men, particularly in the context of metabolic disorders. Early detection and intervention for metabolic syndrome and insulin resistance may help to mitigate their negative impact on male sexual function.